DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG8195 and Slc35f5

DIOPT Version :9

Sequence 1:	NP_611049.1	Gene:	CG8195 / 36725	FlyBaseID:	FBgn0034032	Length:	449	Species:	Drosophila melanogaster
Sequence 2:	XP_006249733.1	Gene:	Slc35f5 / 288993	RGDID:	1308125	Length:	546	Species:	Rattus norvegicus

Alignment Length:	461	Identity:	203/461 - (44%)
Similarity:	297/461 - (64%)	Gaps:	34/461 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 QRLLLGISILVLVDVVWVSSSELTKFLYNEANFDKPFFCTYFKTSMFSIYLLVIGILAPWKESCE 70
            :|:.|||.||:||||:||:|||||.:::.:  ::||||.|:.|||||.:|||...|..||::.|.
  Rat    89 RRMALGIVILLLVDVIWVASSELTSYVFTQ--YNKPFFSTFAKTSMFVLYLLGFIIWKPWRQQCT 151

  Fly    71 RQ-NGNYAMMEQNADDENYY-------SNQAVLGDPTYVPIRSPHLGAGGQSNGTSNSISGTESD 127
            |. .|..|..  .||.|.|:       |..:.|.:|.|||::...|    .|....::..|||..
  Rat   152 RGFRGKPAAF--FADAEGYFAACTTDSSMSSSLSEPLYVPVKFHDL----PSEKLESTNIGTEKP 210

  Fly   128 DSSVRSVRFSKMAEVREMSAHEATDALMARLSYAASLRIRRQKTHHKT---------AKTALLFC 183
            ....| ||||.:.|:|::.:..|.:|.::|:||..   ::.|::..||         ||.:..||
  Rat   211 PKKSR-VRFSNIMEIRQLPSSHALEAKLSRMSYPT---VKDQESILKTVGKLTATQVAKISFFFC 271

  Fly   184 LLWFAANYFFQLALEMDEAAMITLVSSTSSFFIICLAAVFPSATGDKLTITKVIAVAMNIGGVVA 248
            .:||.||..:|.||...:.|::.::||||..|.:.|||||||.:||:.|::|::||.::|||||.
  Rat   272 FVWFLANLSYQEALSDTQVAIVNILSSTSGLFTLILAAVFPSNSGDRFTLSKLLAVILSIGGVVL 336

  Fly   249 ITMNDLHDT--KMTRGVLLALFSAFFYAAYLVFVKRKSDTEEKVDIPLFFGFVGLWNMLLLWPIF 311
            :.::....:  :.|.|.:.:|..|.|||.|:|.:|||.|.|:|:|||:|||||||:|:|||||.|
  Rat   337 VNLSGSEKSAGRDTIGSIWSLAGAMFYAVYIVMIKRKVDREDKLDIPMFFGFVGLFNLLLLWPGF 401

  Fly   312 FILHFTKIETFELPSQGQFALLFLNGLVGTVLSEALWLWGCFLTSSLIGTLAMSLQIPLAILFDV 376
            |:||:|..|.||.|::.....:.:|||:||||||.|||||||||||||||||:||.|||:|:.|:
  Rat   402 FLLHYTGFEDFEFPNKVVLLCIIINGLIGTVLSEFLWLWGCFLTSSLIGTLALSLTIPLSIIADM 466

  Fly   377 LLKNKPYSPMFYMGSIPIFVALVFVSLLMRNDDSDPLMKLFRIVYRKVCRCHKPSIVRVNDD-EQ 440
            .::...:|.:|:.|:||:|.:...|:||...::.||:|...|.|:..:||.|:  |.||::| ||
  Rat   467 CMQKVQFSWLFFAGAIPVFFSFFIVTLLCHYNNWDPVMVGVRRVFAFICRKHR--IQRVSEDSEQ 529

  Fly   441 QESLIS 446
            .|||||
  Rat   530 CESLIS 535

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8195	NP_611049.1	2A78	153..399	CDD:273359	121/256 (47%)
CG8195	NP_611049.1	EamA	260..403	CDD:279264	80/142 (56%)
Slc35f5	XP_006249733.1	EamA	<251..339	CDD:279264	37/87 (43%)
		RhaT	<268..493	CDD:223769	113/224 (50%)
		EamA	350..493	CDD:279264	80/142 (56%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166340370
Domainoid	1	1.000	174	1.000	Domainoid score	I3586
eggNOG	1	0.900	-	-		E1_COG0697
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H5745
Inparanoid	1	1.050	359	1.000	Inparanoid score	I2147
OMA	1	1.010	-	-		QHG55723
OrthoDB	1	1.010	-	-		D1084257at2759
OrthoFinder	1	1.000	-	-		FOG0004517
OrthoInspector	1	1.000	-	-		oto96906
orthoMCL	1	0.900	-	-		OOG6_103193
Panther	1	1.100	-	-	LDO	PTHR23051
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X4898
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	16	15.770