DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8195 and SPBC405.03c

DIOPT Version :9

Sequence 1:	NP_611049.1	Gene:	CG8195 / 36725	FlyBaseID:	FBgn0034032	Length:	449	Species:	Drosophila melanogaster
Sequence 2:	NP_596306.1	Gene:	SPBC405.03c / 2540974	PomBaseID:	SPBC405.03c	Length:	341	Species:	Schizosaccharomyces pombe

Alignment Length:	407	Identity:	120/407 - (29%)
Similarity:	182/407 - (44%)	Gaps:	87/407 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly    10 LGISILVLVDVVWVSSSELTKFLYNEANFDKPFFCTYFKTSMFSIYLLVIGILAPWKESCERQNG 74
            ||:.:|:.|..:|:.||.||..|.::.||..||..||..|..|..||:      ||
pombe    11 LGVVLLLFVVFLWLISSFLTSSLLDDDNFFSPFLITYINTGTFVFYLI------PW--------- 60

  Fly    75 NYAMMEQNADDENYYSNQAVLGDPTYVPIRSPHLGAGGQSNGTSNSISGTESDDSSVRSVRFSKM 139
                         |:|                                     :...|..|....
pombe    61 -------------YFS-------------------------------------EKKTRKHRLMSE 75

  Fly   140 AEVREMSAHEATDALMARLSYAASLRIRRQKTHHKTAKTALLFCLLWFAANYFFQLALEMDEAAM 204
            ..:.| |.|:::..|..|.:.....|        :||..:|.||::|||||||...:|.....|.
pombe    76 LSMYE-SVHDSSFNLGTRPNSPLGFR--------QTAYLSLGFCIIWFAANYFSNSSLGFTNVAS 131

  Fly   205 ITLVSSTSSFFIICLAAVFPSATGDKLTITKVIAVAMNIGGVVAITMN-----DLHDTKMTR--- 261
            .|::||.|.||.:.|..:   ...::.|::|::|:..::|||:.:...     ||:|:..:|
pombe   132 FTIISSMSGFFTLGLGTI---VNVERFTLSKLLALMASVGGVIIVVTQDAKQADLNDSPPSRPAL 193

  Fly   262 GVLLALFSAFFYAAYLVFVKRKSDTEEKVDIPLFFGFVGLWNMLLLWPIFFILHFTKIETFELPS 326
            |...||.:|..|..|.|.||.....|..|...||||.|||::::||||...|||...:|.|.|||
pombe   194 GNAYALLAALLYGCYSVMVKFHITEESCVSTRLFFGLVGLFDLILLWPFLIILHLYGVERFSLPS 258

  Fly   327 -QGQFALLFLNGLVGTVLSEALWLWGCFLTSSLIGTLAMSLQIPLAILFDVLLKNKPYSPMFYMG 390
             .....:|.:|..: |.:|:.||:....:||.|:.|:.|||.||||:.||:|||....:....:|
pombe   259 TTAGLIVLIINASI-TFVSDYLWVIAMLMTSPLLVTVGMSLSIPLALFFDILLKGHYLNFSLILG 322

  Fly   391 SIPIFVALVFVSLLMRN 407
            |:.:|...:.|:...:|
pombe   323 SLLVFAGFIVVNYNQQN 339

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8195	NP_611049.1	2A78	153..399	CDD:273359	89/254 (35%)
CG8195	NP_611049.1	EamA	260..403	CDD:279264	57/146 (39%)
SPBC405.03c	NP_596306.1	RhaT	87..339	CDD:223769	90/263 (34%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0697
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H5745
Inparanoid	1	1.050	198	1.000	Inparanoid score	I1010
OMA	1	1.010	-	-		QHG55723
OrthoFinder	1	1.000	-	-		FOG0004517
OrthoInspector	1	1.000	-	-		oto101168
orthoMCL	1	0.900	-	-		OOG6_103193
Panther	1	1.100	-	-	LDO	PTHR23051
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1847
SonicParanoid	1	1.000	-	-		X4898
TreeFam	1	0.960	-	-
	13	12.860