DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG8195 and slc35f5

DIOPT Version :9

Sequence 1:	NP_611049.1	Gene:	CG8195 / 36725	FlyBaseID:	FBgn0034032	Length:	449	Species:	Drosophila melanogaster
Sequence 2:	NP_001135524.1	Gene:	slc35f5 / 100216066	XenbaseID:	XB-GENE-5992645	Length:	473	Species:	Xenopus tropicalis

Alignment Length:	468	Identity:	199/468 - (42%)
Similarity:	304/468 - (64%)	Gaps:	48/468 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 QRLLLGISILVLVDVVWVSSSELTKFLYNEANFDKPFFCTYFKTSMFSIYLLVIGILAPWKESCE 70
            :||||||.||:|||::||:|||||.:::.|  ::||||.|:.|||||.:|||...:..||::.|.
Frog    15 RRLLLGIVILLLVDIIWVASSELTSYIFQE--YNKPFFSTFAKTSMFVLYLLGFIVWRPWRQQCS 77

  Fly    71 RQNGNYAMMEQN----ADDENYY-------SNQAVLGDPTYVPIR-----SPHLGAGGQSNGTSN 119
            :     ...::|    ||.|.|:       :....|.:|.|||::     :..:||
Frog    78 K-----CFRDRNSTFFADAEGYFPACTTDHTLTHALSEPLYVPVKFHDLQNEKVGA--------- 128

  Fly   120 SISGTESDDSSVRS--VRFSKMAEVREMSAHEATDALMARLSYA------ASLRIRRQKTHHKTA 176
               |..:.|.:|::  ||||.:.|||::.:.:|.:|.::|::..      |.||...:.|..:.|
Frog   129 ---GRVAPDKAVKAPRVRFSNLMEVRQLPSSQAVEAKLSRMANPPIRQSDAMLRGVAKLTVCQVA 190

  Fly   177 KTALLFCLLWFAANYFFQLALEMDEAAMITLVSSTSSFFIICLAAVFPSATGDKLTITKVIAVAM 241
            |.:..||.:||.|||.:|.||...:.|::.::||||..|.:.||:||||.:||:.|::|::|||:
Frog   191 KISFFFCFVWFLANYSYQEALSDTQVAIVNIISSTSGLFTLILASVFPSNSGDRFTLSKLLAVAL 255

  Fly   242 NIGGVVAITM--NDLHDTKMTRGVLLALFSAFFYAAYLVFVKRKSDTEEKVDIPLFFGFVGLWNM 304
            ::||||.:::  :|....|.|.|.:.::..|..||.|:|.:|||.|.|:|:|||:|||||||:|:
Frog   256 SVGGVVLVSLSGSDQSRGKDTIGSIWSVLGAVLYAVYIVMLKRKVDREDKLDIPMFFGFVGLFNL 320

  Fly   305 LLLWPIFFILHFTKIETFELPSQGQFALLFLNGLVGTVLSEALWLWGCFLTSSLIGTLAMSLQIP 369
            |||||.||:||:|..|.||.||:..:..:.:|||:||||||.|||||||||||||||||:||.||
Frog   321 LLLWPGFFLLHYTGFEAFEFPSKLVWIYIVINGLIGTVLSEFLWLWGCFLTSSLIGTLALSLTIP 385

  Fly   370 LAILFDVLLKNKPYSPMFYMGSIPIFVALVFVSLLMRNDDSDPLMKLFRIVYRKVCRCHKPSIVR 434
            |:::.|:.|:...:|.:|:.|::|:|::...|:||...::.||:|...|.|:..:||.|:  |.|
Frog   386 LSVIADMCLQKVRFSWVFFAGAVPVFISFFVVTLLCHYNNWDPVMVGIRRVFAFICRKHR--IQR 448

  Fly   435 VNDD-EQQESLIS 446
            |:|| ||.:|||:
Frog   449 VSDDSEQSQSLIA 461

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8195	NP_611049.1	2A78	153..399	CDD:273359	120/253 (47%)
CG8195	NP_611049.1	EamA	260..403	CDD:279264	78/142 (55%)
slc35f5	NP_001135524.1	RhaT	<192..419	CDD:223769	113/226 (50%)
		EamA	<201..265	CDD:279264	30/63 (48%)
		EamA	276..419	CDD:279264	78/142 (55%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	168	1.000	Domainoid score	I3774
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	294	1.000	Inparanoid score	I2696
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0004517
OrthoInspector	1	1.000	-	-		oto103599
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X4898
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	6	6.050