Protein Alignment eIF2Bgamma and APS2

DIOPT Version :10

• Sequence 1: NP_611046.2
• Gene: eIF2Bgamma / 36722
• FlyBaseID: FBgn0034029
• Length: 455
• Species: Drosophila melanogaster
• Sequence 2: NP_001322344.1
• Gene: APS2 / 837066
• AraportID: AT1G05610
• Length: 482
• Species: Arabidopsis thaliana
• Alignment Length: 490
• Identity: 93/490 - (18%)
• Similarity: 173/490 - (35%)
• Gaps: 152/490 - (31%)

  Fly     6 AVVFAAGRGTRLPEVLGDAPKCLLPVGP-YPLIWYPLNLLQQHNFTEVIVVVLEQEKLEIQSALE 69
            |:||..|..:.|..:.....|..:|:.. |.||...::.......|::..:          :...
plant    57 AIVFGGGSDSELYPLTKTRSKGAIPIAANYRLIDAVISNCINSGITKIYAI----------TQFN 111

  Fly    70 NTPLKLRLD-------------------YATIPSDGDF-GTADSLR---YIYDKIK-SDFLVVSC 110
            :|.|...|.                   |.::...|.| ||||::|   :::::.. ::|||:..
plant   112 STSLNSHLSKAYSGFGLGKDRFVEVIAAYQSLEDQGWFQGTADAIRRCLWVFEEFPVTEFLVLPG 176

  Fly   111 DLVSNVSLYPLINKFREHDAALAMLLFPS--------GF-ESDVVMPGPKSKHKPERDLIGIHAA 166
            ..:..:....||...|...|.:.::...|        || |.|......:...|.::|||.:  |
plant   177 HHLYKMDYKMLIEDHRRSRADITIVGLSSVTDHDFGFGFMEVDSTNAVTRFTIKGQQDLISV--A 239

  Fly   167 TQRLAFVSAASDCEETLNIQRHLLKNRGRLDVYSRLVDAHVYVL-KKWVIDYLRRKENISTFKGE 230
            .:........|.|.                     :..|.:||: ::.::..||.
plant   240 NRTATRSDGTSSCS---------------------VPSAGIYVIGREQMVKLLRE---------- 273

  Fly   231 FLPHLIKKQHSKRPPKTVQDTTSEV--GVVTKNEDHVLH-YVGHTILDQKITQTSLFNQSLSQSP 292
               .|||.          :|..||:  |.:::......| :.|:.   :.:.....:.::..:|
plant   274 ---CLIKS----------KDLASEIIPGAISEGMKVKAHMFDGYW---EDVRSIGAYYRANMES- 321

  Fly   293 YHGDIVRCYGIQAPRDAIGVRVNNTLSFLAINRKLASIWNNLCGEKHPL------ISPGAVVKST 351
                |.||.                   |.:|.:   .::..|    ||      :.|.::..:.
plant   322 ----IKRCR-------------------LDLNYR---FYDRQC----PLYTMPRCLPPSSMSVAV 356

  Fly   352 QTKEIIAADNAKLSEKTSLNFSVFGPNCIISPKNIVANSLIMSNAIVE---------EGCNIDNC 407
            .|..||.  :..:.:|..:..||.|....|:.:.||.:|:|:.:.|.|         :...|:..
plant   357 ITNSIIG--DGCILDKCVIRGSVVGMRTRIADEVIVEDSIIVGSDIYEMEEDVRRKGKEKKIEIR 419

  Fly   408 I-IGHRAQVKSGSVLKNCIIGPNYV------VEEG 435
            | ||.:::::...|.||..||.|.:      ||||
plant   420 IGIGEKSRIRRAIVDKNARIGKNVMIINRDNVEEG 454

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
eIF2Bgamma	NP_611046.2	eIF-2B_gamma_N	4..215	CDD:133041	44/243 (18%)
		LbH_eIF2B_gamma_C	357..437	CDD:100057	26/95 (27%)
APS2	NP_001322344.1	PLN02241	52..482	CDD:215133	93/490 (19%)