Protein Alignment Runx2 and RunxA

DIOPT Version :9

• Sequence 1: XP_038939882.1
• Gene: Runx2 / 367218
• RGDID: 2282
• Length: 652
• Species: Rattus norvegicus
• Sequence 2: NP_001259747.1
• Gene: RunxA / 4379817
• FlyBaseID: FBgn0083981
• Length: 663
• Species: Drosophila melanogaster
• Alignment Length: 286
• Identity: 131/286 - (45%)
• Similarity: 160/286 - (55%)
• Gaps: 65/286 - (22%)

  Rat   212 RTMVEIIADHPAELVRTDSPNFLCSVLPSHWRCNKTLPVAFKVVALGEVPDGTVVTVMAGNDENY 276
            ||:.:.:.:||.||:||.||.|:|:|||.|||.|||||||||||:||::.|||:|||.|||||||
  Fly    86 RTLGDFLTEHPGELIRTSSPLFVCTVLPPHWRSNKTLPVAFKVVSLGDIMDGTMVTVRAGNDENY 150

  Rat   277 SAELRNASAVMKNQVARFNDLRFVGRSGRGKSFTLTITVFTNPPQVATYHRAIKVTVDGPREPRR 341
            .|||||.:||||||||:||||||||||||||||||||||.||||.:|||::|||||||||||||
  Fly   151 CAELRNCTAVMKNQVAKFNDLRFVGRSGRGKSFTLTITVSTNPPHIATYNKAIKVTVDGPREPR- 214

  Rat   342 HRQKLDDSKPSLFSDRLSDLGRIPHPSMRVGVPPQNPRPSLNSAPSPFNPQGQSQITDPR----- 401
                   ||     ..||.||:           .|....:....|..|:       |||.
  Fly   215 -------SK-----TMLSLLGQ-----------QQQFHFAFGQRPFHFS-------TDPLSGFRM 249

  Rat   402 ------QTQSSPPWSYDQSYPSYLSQMTSPSIHS-TTPLSSTRGTGLPAI--------------- 444
                  |:.|:..|.|..:..:|...:.|..:.| |||.|:....  ||:
  Fly   250 PPIGNCQSASNTHWGYGSAASAYSPYLASSGLSSCTTPTSAQFNN--PALGFTCSSNDQSNNQDF 312

  Rat   445 -----TDVPRRISDSEPSTLDSQSST 465
                 .|....:.||..|.||...|:
  Fly   313 GGATNRDCVPMLPDSTASDLDQHLSS 338

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Runx2	XP_038939882.1	Runt	217..343	CDD:395684	97/125 (78%)
		PHA03247	<319..606	CDD:223021	50/179 (28%)
RunxA	NP_001259747.1	Runt	95..216	CDD:279225	97/128 (76%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3982
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000993
OrthoInspector	1	1.000	-	-		mtm8944
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	6	5.770