Protein Alignment Khc-73 and HIK

DIOPT Version :9

• Sequence 1: NP_001261000.1
• Gene: Khc-73 / 36718
• FlyBaseID: FBgn0019968
• Length: 1957
• Species: Drosophila melanogaster
• Sequence 2: NP_173273.2
• Gene: HIK / 838418
• AraportID: AT1G18370
• Length: 974
• Species: Arabidopsis thaliana
• Alignment Length: 1151
• Identity: 260/1151 - (22%)
• Similarity: 464/1151 - (40%)
• Gaps: 264/1151 - (22%)

  Fly     4 DKIKVAVRVRPFNRREIELDTKCIVEMEKQQTILQNPPPLEKIERKQPKTFAFDHCFYSLNPEDE 68
            :||.|.||:||.|:||:....:...|.....||:..|...|::..:  .:|.||..|   .||
plant    30 EKIVVTVRLRPMNKRELLAKDQVAWECVNDHTIVSKPQVQERLHHQ--SSFTFDKVF---GPE-- 87

  Fly    69 NFASQETVFDCVGRGILDNAFQGYNACIFAYGQTGSGKSYTMMGTQESKGIIPRLCDQLFSAIAN 133
              :..|.|::...:.:..:|..|.||.|||||||.|||:|||      :|:..:..:.:::.|.
plant    88 --SLTENVYEDGVKNVALSALMGINATIFAYGQTSSGKTYTM------RGVTEKAVNDIYNHII- 143

  Fly   134 KSTPELMYKVEVSYMEIYNEKVHDLLDPKPNKQSLKVREHNVMGPYVDGLSQLAVTSYQDIDNLM 198
             .|||..:.:::|.:|||||.|.|||: ..:.::||:.:....|..|:.|.:....:...:.:|:
plant   144 -KTPERDFTIKISGLEIYNENVRDLLN-SDSGRALKLLDDPEKGTVVEKLVEETANNDNHLRHLI 206

  Fly   199 TEGNKSRTVAATNMNAESSRSHAVFSVVLTQILTDQATGVSGEKVSRMSLVDLAGSERAVKTGAV 263
            :.....|.|..|.:|..|||||.:..:.:.....:.:..|.....| ::.|||||||||.::.|.
plant   207 SICEAQRQVGETALNDTSSRSHQIIRLTIQSTHRENSDCVRSYMAS-LNFVDLAGSERASQSQAD 270

  Fly   264 GDRLKEGSNINKSLTTLGLVISKLADQSNGKKSGNDKFVPYRDSVLTWLLKDNLGGNSRTVMVAT 328
            |.||:||.:||.||.||..||.||   |.||:||:   :|||||.||.:|:.:||||:||.::.|
plant   271 GTRLREGCHINLSLMTLTTVIRKL---SVGKRSGH---IPYRDSKLTRILQHSLGGNARTAIICT 329

  Fly   329 ISPSADNYEETLSTLRYADRAKRIVNHAVVN-EDPNARIIRELRHEVETLRSMLKHATGSPVGDV 392
            :||:..:.|::.:||.:|:|||.:.|:|.|| ...:.::::.|:.||..|.:  :..|..|..:.
plant   330 LSPALAHVEQSRNTLYFANRAKEVTNNAHVNMVVSDKQLVKHLQKEVARLEA--ERRTPGPSTEK 392

  Fly   393 QDKLAESENLMKQISQTWEEKLVKTERIQNERQQALEKMGISVQASGIKVEKNKYYLVNLNADPS 457
            ..|:.:.|..:.::.:..::..::.|.::.:.|      |...|..|:    |.:.    :.||.
plant   393 DFKIQQMEMEIGELRRQRDDAQIQLEELRQKLQ------GDQQQNKGL----NPFE----SPDPP 443

  Fly   458 LNELLVYYL------KDRTLIGGRTISGQQPDIQLSGLGIQPEHCVITIEDSGLYMEPVQGARCF 516
            :.:.|.|.:      :::||  .|....::..::.|.:. |......|:......:|.:| .:..
plant   444 VRKCLSYSVAVTPSSENKTL--NRNERARKTTMRQSMIR-QSSTAPFTLMHEIRKLEHLQ-EQLG 504

  Fly   517 VNGSAAVEKTPLQNGDRILWGNHHFFRVNSPKSNNTSMCASEPQTPAQLIDYNFARDEIMQNELS 581
            ...:.|:|  .||.            .|...:..|.....:..:..|::.:....:...|..|:.
plant   505 EEATKALE--VLQK------------EVACHRLGNQDAAQTIAKLQAEIREMRTVKPSAMLKEVG 555

  Fly   582 N--DPIQTAIARLE----RQHEEDKQVA-LEKQRQEYERQFQQLRNILS-PSTPYAPYAPYDPLR 638
            :  .|.::..|.|:    |.|.:...:| ||:|.:..::...:|  ::| ||.          :.
plant   556 DVIAPNKSVSANLKEEITRLHSQGSTIANLEEQLESVQKSIDKL--VMSLPSN----------IS 608

  Fly   639 MGKITPNTPTSQMRVEKWAQERDEMFRRSLGQLKTDIMRANSLVQEANFLAEEMEKKTKFSVTLQ 703
            .|..||.|.....:.:|               .|...:..:|.....|||.......:.....|.
plant   609 AGDETPKTKNHHHQSKK---------------KKLLPLTPSSASNRQNFLKSPCSPLSASRQVLD 658

  Fly   704 IPPANLSPNRR-----RGAFVSEPAILVKRTNSGSQIWTMEK-LENKLIDMREMYQEHKERVLNG 762
            ....|.:|...     |||          .|..||:..|.:| .|:..:..||....::..
plant   659 CDAENKAPQENNSSAARGA----------TTPQGSEKETPQKGEESGDVSSREGTPGYRRS---- 709

  Fly   763 LDEDNAKPQDPFYESQENHNLIGVANIFLEVLFHDVKLDYHTPIISQQGEVAGRLQVEIERIAGQ 827
             ...|.|.....:::....|:..:.....|:.....||.|...::..|       .:|:|
plant   710 -SSVNMKKMQQMFQNAAEENVRSIRAYVTELKERVAKLQYQKQLLVCQ-------VLELE----- 761

  Fly   828 MPQDRMCESVSESSGDSRDEYDDPV--DPTSNQITCRVTIKCASGLPLSLSNFVFCQYTFWGHQE 890
                     .::.:|.|.:..::.:  |...||:...:|
plant   762 ---------ANDGAGYSVENEENTIMEDEEQNQVAWHIT-------------------------- 791

  Fly   891 MVVPVINAESTAHDQNMVFKFEHTQDFTVTINEEFLEHCIEGALSIEVWG-------HRSAGFSK 948
                                              |:|   |....||:|.       ||:..:..
plant   792 ----------------------------------FIE---ERQQIIELWHVCHVSIIHRTQFYLL 819

  Fly   949 TKGWEVEQ--QQAKARSLVDRWAELSRKIELWVEIHELNDNGEYSPVEVTNRNEV-LTGGIYQLR 1010
            .||.:.:|  .:.:.|.|.            |:|.| |.:.|..:|....:.:.| |:..|..||
plant   820 FKGDQADQIYMEVELRRLT------------WLEQH-LAEVGNATPARNCDESVVSLSSSIKALR 871

  Fly  1011 QGQQ---RRVNVRVKPVQNSGTLPIICQSIVNVAIGSVTVRSRLQRPLDSYQEEDLTVLREKWSE 1072
            :.::   :|||.|:.|.:..                  .:..:...||:..|.: |..:.:.|::
plant   872 REREFLAKRVNSRLTPEERE------------------ELYMKWDVPLEGKQRK-LQFVNKLWTD 917

  Fly  1073 ALGRRRQYLDQQIQMLIKK----EEKNEQERERELSLV-----HQW 1109
            ....|  ::.:..:::.|.    |..|..:...||:..     .||
plant   918 PYDSR--HVQESAEIVAKLVGFCESGNISKEMFELNFAVPSDKRQW 961

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Khc-73	NP_001261000.1	KISc_KIF1A_KIF1B	4..359	CDD:276816	128/354 (36%)
		KISc	6..359	CDD:214526	127/352 (36%)
		Kinesin_assoc	356..468	CDD:292801	21/118 (18%)
		FHA	446..546	CDD:238017	17/105 (16%)
		KIF1B	741..786	CDD:289208	6/44 (14%)
		DUF3694	<1196..1252	CDD:289256
		CAP_GLY	1786..1850	CDD:279625
HIK	NP_173273.2	KISc_CENP_E	31..353	CDD:276825	126/346 (36%)
		Kinesin	37..353	CDD:278646	122/340 (36%)
		DUF3490	792..955	CDD:288820	40/199 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910