DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Khc-73 and ncd

DIOPT Version :9

Sequence 1:	NP_001261000.1	Gene:	Khc-73 / 36718	FlyBaseID:	FBgn0019968	Length:	1957	Species:	Drosophila melanogaster
Sequence 2:	NP_001287592.1	Gene:	ncd / 43517	FlyBaseID:	FBgn0002924	Length:	700	Species:	Drosophila melanogaster

Alignment Length:	369	Identity:	132/369 - (35%)
Similarity:	196/369 - (53%)	Gaps:	45/369 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 IKVAVRVRPFNRREIELDTKCIVEMEKQQTI-LQNPPPLEKIERKQPKTFAFDHCFYSLNPEDEN 69
            |:|..|:||....| |....|......:.|: ||:.....|.:..| :.|:||..|:.|
  Fly   349 IRVFCRIRPPLESE-ENRMCCTWTYHDESTVELQSIDAQAKSKMGQ-QIFSFDQVFHPL------ 405

  Fly    70 FASQETVFDCVGRGILDNAFQGYNACIFAYGQTGSGKSYTMMGTQESKGIIPRLCDQLFSAIANK 134
             :||..:|:.|. .::.:|..|||.||||||||||||:|||.|..||.|:|||..|.||.:|...
  Fly   406 -SSQSDIFEMVS-PLIQSALDGYNICIFAYGQTGSGKTYTMDGVPESVGVIPRTVDLLFDSIRGY 468

  Fly   135 STPELMYKVEVSYMEIYNEKVHDLLDPKPNKQSLKVREHNVMGPYVDGLSQLAVTSYQDIDNLMT 199
            ......|:::.:::|||||.::|||..:.....:::.::|....||..:::..|.....:.:||.
  Fly   469 RNLGWEYEIKATFLEIYNEVLYDLLSNEQKDMEIRMAKNNKNDIYVSNITEETVLDPNHLRHLMH 533

  Fly   200 EGNKSRTVAATNMNAESSRSHAVFSVVLTQILTDQATGVSGEK----VSRMSLVDLAGSERAVKT 260
            ....:|..|:|..|..|||||||..:.|        .|...||    |..::|||||||| :.||
  Fly   534 TAKMNRATASTAGNERSSRSHAVTKLEL--------IGRHAEKQEISVGSINLVDLAGSE-SPKT 589

  Fly   261 GAVGDRLKEGSNINKSLTTLGLVISKLADQSNGKKSGNDKFVPYRDSVLTWLLKDNLGGNSRTVM 325
            ..   |:.|..|||:||:.|..||..|..:.:        .:|||:|.||.||..:|||||:|:|
  Fly   590 ST---RMTETKNINRSLSELTNVILALLQKQD--------HIPYRNSKLTHLLMPSLGGNSKTLM 643

  Fly   326 VATISPSADNYEETLSTLRYA--------DRAK--RIVNHAVVN 359
            ...:||..|.::|::.:||:|        .:||  |.:|::|.|
  Fly   644 FINVSPFQDCFQESVKSLRFAASVNSCKMTKAKRNRYLNNSVAN 687

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Khc-73	NP_001261000.1	KISc_KIF1A_KIF1B	4..359	CDD:276816	131/367 (36%)
		KISc	6..359	CDD:214526	131/367 (36%)
		Kinesin_assoc	356..468	CDD:292801	2/4 (50%)
		FHA	446..546	CDD:238017
		KIF1B	741..786	CDD:289208
		DUF3694	<1196..1252	CDD:289256
		CAP_GLY	1786..1850	CDD:279625
ncd	NP_001287592.1	KISc_C_terminal	346..672	CDD:276817	126/352 (36%)
ncd	NP_001287592.1	KISc	348..678	CDD:214526	128/358 (36%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45437754
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.840