DRSC/TRiP Functional Genomics Resources

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Protein Alignment Khc-73 and nod

DIOPT Version :9

Sequence 1:NP_001261000.1 Gene:Khc-73 / 36718 FlyBaseID:FBgn0019968 Length:1957 Species:Drosophila melanogaster
Sequence 2:NP_001285129.1 Gene:nod / 32107 FlyBaseID:FBgn0002948 Length:666 Species:Drosophila melanogaster


Alignment Length:497 Identity:139/497 - (27%)
Similarity:231/497 - (46%) Gaps:82/497 - (16%)


- Green bases have known domain annotations that are detailed below.


  Fly     6 IKVAVRVRPF----NRREIELDTKCIVEMEKQQTILQNPPPLEK----IERKQPKTFAFDHCFYS 62
            :::|||..|:    .|||              .:::|.||..:.    :::.:   |.|||.|.:
  Fly     9 VRIAVREAPYRQFLGRRE--------------PSVVQFPPWSDGKSLIVDQNE---FHFDHAFPA 56

  Fly    63 LNPEDENFASQETVFDCVGRGILDNAFQGYNACIFAYGQTGSGKSYTMMGT------QESKGIIP 121
            .       .||:.::..:...::|...:|:.....||||||:||||:|..|      .|..||:|
  Fly    57 T-------ISQDEMYQALILPLVDKLLEGFQCTALAYGQTGTGKSYSMGMTPPGEILPEHLGILP 114

  Fly   122 RLCDQLFSAI-ANKSTPELMYKVEVSYMEIYNEKVHDLLDPKPNKQSLKVREHNVMGPYVDGLSQ 185
            |....:|..: |.:...:...:|..|::||||||..|||...|:...:..|        ....:.
  Fly   115 RALGDIFERVTARQENNKDAIQVYASFIEIYNEKPFDLLGSTPHMPMVAAR--------CQRCTC 171

  Fly   186 LAVTSYQDIDNLMTEGNKSRTVAATNMNAESSRSHAVFSVVLTQILTDQATGVSGEKVSRMSLVD 250
            |.:.|..|:.:::..|.::|.|..||||:.||||||:.::.:.          |....|||::||
  Fly   172 LPLHSQADLHHILELGTRNRRVRPTNMNSNSSRSHAIVTIHVK----------SKTHHSRMNIVD 226

  Fly   251 LAGSERAVKTGAVGDRLKEGSNINKSLTTLGLVISKLADQSNGKKSGNDKFVPYRDSVLTWLLKD 315
            |||||...:||..|...:||.|||..|.::..|:..:|        .....:||||||||.:|:.
  Fly   227 LAGSEGVRRTGHEGVARQEGVNINLGLLSINKVVMSMA--------AGHTVIPYRDSVLTTVLQA 283

  Fly   316 NLGGNSRTVMVATISPSADNYEETLSTLRYADRAKRI----VNHAVVNEDPNARIIRELRHEVET 376
            :|...|....:|.|||...:..|||||||:...||::    :..|...:...||.....|..:.|
  Fly   284 SLTAQSYLTFLACISPHQCDLSETLSTLRFGTSAKKLRLNPMQVARQKQSLAARTTHVFRQALCT 348

  Fly   377 LRSMLKHATG-SPVGDVQDKLAESENLMKQISQTWEEKLVKTERIQNERQQALEKMGISVQASGI 440
            ..::..:|.. :.:...:.|.:.::.|...:.:|..| |..|.:.:...::.||....:::.|.|
  Fly   349 STAIKSNAANHNSIVVPKSKYSTTKPLSAVLHRTRSE-LGMTPKAKKRARELLELEETTLELSSI 412

  Fly   441 KVEKNKYYLVNLNADPSLNELLVYYLKDRTLIGGRTISGQQP 482
            .::.:...|:..::|..         |||.|:...|  ||:|
  Fly   413 HIQDSSLSLLGFHSDSD---------KDRHLMPPPT--GQEP 443

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Khc-73NP_001261000.1 KISc_KIF1A_KIF1B 4..359 CDD:276816 114/371 (31%)
KISc 6..359 CDD:214526 114/371 (31%)
Kinesin_assoc 356..468 CDD:292801 18/112 (16%)
FHA 446..546 CDD:238017 10/37 (27%)
KIF1B 741..786 CDD:289208
DUF3694 <1196..1252 CDD:289256
CAP_GLY 1786..1850 CDD:279625
nodNP_001285129.1 KISc 8..325 CDD:214526 113/365 (31%)
KISc 8..318 CDD:276812 111/358 (31%)
ComEA 540..648 CDD:224472
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C45437749
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 - - P PTHR24115
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
22.030

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