Protein Alignment Khc-73 and Klp10A

DIOPT Version :10

• Sequence 1: NP_001261000.1
• Gene: Khc-73 / 36718
• FlyBaseID: FBgn0019968
• Length: 1957
• Species: Drosophila melanogaster
• Sequence 2: NP_572687.1
• Gene: Klp10A / 32049
• FlyBaseID: FBgn0030268
• Length: 805
• Species: Drosophila melanogaster
• Alignment Length: 557
• Identity: 153/557 - (27%)
• Similarity: 244/557 - (43%)
• Gaps: 116/557 - (20%)

  Fly     5 KIKVAVRVRPFNRREI---ELDTKCIVEMEKQQTILQNPP--PLEKIERKQPKTFAFDHCFYSLN 64
            :|.|.||.||.:|:|:   |:|   ::.:.::..::.:.|  .::..:..:...|.||   |:.|
  Fly   278 QITVCVRKRPISRKEVNRKEID---VISVPRKDMLIVHEPRSKVDLTKFLENHKFRFD---YAFN 336

  Fly    65 PEDENFASQETVFDCVGRGILDNAFQGYNACIFAYGQTGSGKSYTMMG-----TQESK-GIIPRL 123
            ...:|    ..|:....:.::...|:|..|..||||||||||::||.|     .|:.| ||....
  Fly   337 DTCDN----AMVYKYTAKPLVKTIFEGGMATCFAYGQTGSGKTHTMGGEFNGKVQDCKNGIYAMA 397

  Fly   124 CDQLFSAIANKSTPELMYKVEVSYMEIYNEKVHDLLDPKPNKQSLKVREHNVMGPYVDGLSQLAV 188
            ...:|..:.......:...|..|:.|||:.||.|||.   :||.|:|.|.......|.||::..|
  Fly   398 AKDVFVTLNMPRYRAMNLVVSASFFEIYSGKVFDLLS---DKQKLRVLEDGKQQVQVVGLTEKVV 459

  Fly   189 TSYQDIDNLMTEGNKSRTVAATNMNAESSRSHAVFSVVLTQILTDQATGVSGEKVSRMSLVDLAG 253
            ...:::..|:..||.:||...|:.|:.||||||||.:||.   ...:|.:.|    :.|.:||||
  Fly   460 DGVEEVLKLIQHGNAARTSGQTSANSNSSRSHAVFQIVLR---PQGSTKIHG----KFSFIDLAG 517

  Fly   254 SERAVKTGAVGDRLK-EGSNINKSLTTLGLVISKLADQSNGKKSGNDKFVPYRDSVLTWLLKDN- 316
            :||.|.|.:...:.: ||:.|||||..|...|..|     ||:|.:   :|:|.|.||.:|:|:
  Fly   518 NERGVDTSSADRQTRMEGAEINKSLLALKECIRAL-----GKQSAH---LPFRVSKLTQVLRDSF 574

  Fly   317 LGGNSRTVMVATISPSADNYEETLSTLRYADRAKRIVNHAVV----------------NEDPNAR 365
            :|..|:|.|:|.|||...:.|.||:|||||||.|.:|...:|                .|:....
  Fly   575 IGEKSKTCMIAMISPGLSSCEHTLNTLRYADRVKELVVKDIVEVCPGGDTEPIEITDDEEEEELN 639

  Fly   366 IIRELRHEV-----------ETLRSMLKHATGSPV--------------------------GDVQ 393
            ::....|::           ...|:...|.:|:.:                          .::.
  Fly   640 MVHPHSHQLHPNSHAPASQSNNQRAPASHHSGAVIHNNNNNNNKNGNAGNMDLAMLSSLSEHEMS 704

  Fly   394 DKLAESENLMKQISQTWEEKLVKTERIQNERQQALEKMGISVQASGIKVEKNKYYLVNLNADPSL 458
            |:|......:..:.|| ||.:|:..|..|...:..           :...|..|.|.|
  Fly   705 DELIVQHQAIDDLQQT-EEMVVEYHRTVNATLETF-----------LAESKALYNLTN------- 750

  Fly   459 NELLVYYLKDRTLIGGRTISGQQPDIQLSGLGIQPEH 495
               .|.|.:|.....|.::..|..||.:....:..|:
  Fly   751 ---YVDYDQDSYCKRGESMFSQLLDIAIQCRDMMAEY 784

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Khc-73	NP_001261000.1	KISc_KIF1A_KIF1B	4..359	CDD:276816	127/382 (33%)
		Kinesin_assoc	356..468	CDD:465047	21/164 (13%)
		FHA_KIF13	446..547	CDD:438758	11/50 (22%)
		KIF1B	741..786	CDD:463574
		DUF3694	989..1243	CDD:463599
		CAP_GLY	1785..1850	CDD:460154
Klp10A	NP_572687.1	KISc_KIF2_like	278..608	CDD:276818	124/357 (35%)