Protein Alignment Khc-73 and cut7

DIOPT Version :9

• Sequence 1: NP_001261000.1
• Gene: Khc-73 / 36718
• FlyBaseID: FBgn0019968
• Length: 1957
• Species: Drosophila melanogaster
• Sequence 2: NP_594527.1
• Gene: cut7 / 2542732
• PomBaseID: SPAC25G10.07c
• Length: 1085
• Species: Schizosaccharomyces pombe
• Alignment Length: 1223
• Identity: 299/1223 - (24%)
• Similarity: 491/1223 - (40%)
• Gaps: 319/1223 - (26%)

  Fly     6 IKVAVRVRPFNRREIELDTKCIVE----MEKQQTILQNPPPLEKIERKQPKTFAFDHCFYSLNPE 66
            |.|.||||....:|:..::...|.    |..:..|..:|..:     ...||:|||..|   .||
pombe    73 INVVVRVRGRTDQEVRDNSSLAVSTSGAMGAELAIQSDPSSM-----LVTKTYAFDKVF---GPE 129

  Fly    67 DENFASQETVFDCVGRGILDNAFQGYNACIFAYGQTGSGKSYTMMG--------TQESKGIIPRL 123
                |.|..:|:.....:|:....|||..||||||||:||:|||.|        ..|..|:|||.
pombe   130 ----ADQLMLFENSVAPMLEQVLNGYNCTIFAYGQTGTGKTYTMSGDLSDSDGILSEGAGLIPRA 190

  Fly   124 CDQLFSAIANKSTPELMYKVEVSYMEIYNEKVHDLLDPKPNKQSLKV-----REHNVMGPYVDGL 183
            ..||||::.|.:..   |.|:.||.|:|||::.|||..:..::..:|     |..||:   :.|:
pombe   191 LYQLFSSLDNSNQE---YAVKCSYYELYNEEIRDLLVSEELRKPARVFEDTSRRGNVV---ITGI 249

  Fly   184 SQLAVTSYQDIDNLMTEGNKSRTVAATNMNAESSRSHAVFSVVL----TQILTDQATGVSGE--- 241
            .:..:.:..|...|:.||:..|.||||..|..|||||::|::.|    :..:||:...::..
pombe   250 EESYIKNAGDGLRLLREGSHRRQVAATKCNDLSSRSHSIFTITLHRKVSSGMTDETNSLTINNNS 314

  Fly   242 ----KVSRMSLVDLAGSERAVKTGAVGDRLKEGSNINKSLTTLGLVISKLADQSNGKKSGNDKFV 302
                :.|::.:|||||||...::||...|.:|...||:||.|||.||:.|.::::        .:
pombe   315 DDLLRASKLHMVDLAGSENIGRSGAENKRARETGMINQSLLTLGRVINALVEKAH--------HI 371

  Fly   303 PYRDSVLTWLLKDNLGGNSRTVMVATISPSADNYEETLSTLRYADRAKRIVNHAVVNEDPNARI- 366
            |||:|.||.||:|:|||.::|.|:.|:|.:..|.|||:|||.||.|||.|.|....|:....::
pombe   372 PYRESKLTRLLQDSLGGKTKTSMIVTVSSTNTNLEETISTLEYAARAKSIRNKPQNNQLVFRKVL 436

  Fly   367 IRELRHEVETLRSMLKHATGSPVGDVQDKLAESENLMKQISQTWEEKLVKTERIQN------ERQ 425
            |::|..::|.|::.| :||....|..   ||||         |::|.:   :|:||      |:.
pombe   437 IKDLVLDIERLKNDL-NATRKKNGVY---LAES---------TYKELM---DRVQNKDLLCQEQA 485

  Fly   426 QALEKMGISVQASGIKVEKNKYYLVNLNADPSLNELLVYYLKDRTLIGGRTISGQQPDIQLSGLG 490
            :.||.:.::|::|                    .|.|.|..|          |.|:...::..|.
pombe   486 RKLEVLDLNVKSS--------------------REQLQYVSK----------SNQEHKKEVEALQ 520

  Fly   491 IQPEHCVITIEDSGLYMEPVQGARCFVNGSAAVEKTPLQNGDRILWGNHHFFRVNSPKSNNTSMC 555
            :|                       .||.|..:|                     |.||.|..:
pombe   521 LQ-----------------------LVNSSTELE---------------------SVKSENEKL- 540

  Fly   556 ASEPQTPAQLIDYNFARDEIMQNELSNDPIQTAIARLERQHEE------DKQVALEKQRQEYERQ 614
                  ..:|:.....|.:...||.....:.|.:::..|:.:|      :|....|:..:|.|..
pombe   541 ------KNELVLEIEKRKKYETNEAKITTVATDLSQYYRESKEYIASLYEKLDRTERNNKENENN 599

  Fly   615 FQQLR-NILSPSTPYAPYAPYDPLRMGKITPNTPTSQMRVEKWAQERDEMFRRSLGQLKTDIMRA 678
            |..|: |:|:....:          .|..|..|......:..:....:|:......||   ::..
pombe   600 FWNLKFNLLTMLRSF----------HGSFTDETNGYFTLLNDFNASMEELLNTHSNQL---LISM 651

  Fly   679 NSLVQEANFLAEEMEK-KTKFSVTLQIPPANLSPNRRRGAFVSEPAILVKRTNSGSQIWTMEKLE 742
            ..:.:....|.|.::. ::..:|          ||......|||                ::..:
pombe   652 TKITEHFQSLDEALQSARSSCAV----------PNSSLDLIVSE----------------LKDSK 690

  Fly   743 NKLIDMREMYQEHKERVLNGLDEDNAKPQDPFYESQENHNLIGVANIFLEVLFHDVKLDYHTPII 807
            |.|:|.    .||             ..||....||:..|  |:::..:| |..|:|..|..  :
pombe   691 NSLLDA----LEH-------------SLQDISMSSQKLGN--GISSELIE-LQKDMKESYRQ--L 733

  Fly   808 SQQGEVAGRLQVEIERIAGQMPQDRMCESVSESSGDSRDEYDDPVDPTSNQITCRVTIKCASGLP 872
            .|:......||...|            ||..|.....|::.|..|.      ||..::..|.
pombe   734 VQELRSLYNLQHTHE------------ESQKELMYGVRNDIDALVK------TCTTSLNDAD--- 777

  Fly   873 LSLSNFVFCQYT-FWGHQEMVVPVIN--AESTAHDQN--MVFKFE----HTQDFTVTI------- 921
            :.||:::..|.: |...|:.::..|.  ..:...:||  :..|.:    |..|....|
pombe   778 IILSDYISDQKSKFESKQQDLIANIGKIVSNFLQEQNESLYTKADILHSHLNDTNSNIRKANEIM 842

  Fly   922 ---NEEFLEHCIEGALSIEVWGHRSAGFSKT--KGWEVEQQQAKA-----RSLVDRWAEL--SRK 974
               :||||.:   .|...|:.|.......||  .|.::...::||     ||:.|....|  |:|
pombe   843 NNRSEEFLRN---AASQAEIVGANKERIQKTVENGSQLLDSKSKAIHSNSRSMYDHCLALAESQK 904

  Fly   975 IELWVEIHELNDNGEYSPVEVTNRNEVLTGGIYQLRQGQQRRVNVRVKPVQNSGTLPIICQSIVN 1039
            ..:.:|:..|:...:    :|...:|..|      ::..|:.:::....|.|:..|
pombe   905 QGVNLEVQTLDRLLQ----KVKEHSEDNT------KEKHQQLLDLLESLVGNNDNL--------- 950

  Fly  1040 VAIGSV-TVRSRLQRPLDSYQEEDLTVLREKWSEALGRRRQ---YLDQQIQ--MLIKKEEKNEQE 1098
              |.|: |..:.||:..| :..:..|.|....:|.||...:   .|:..|:  .|:|.|...:..
pombe   951 --IDSIKTPHTELQKITD-HVLKGTTSLANHTNELLGLGDESLCNLETTIEDTSLVKLETTGDTP 1012

  Fly  1099 RERELSLVHQW------------VSLTEERNAVLVPAPGSGIPGAPASWEPPS 1139
            .:|||.....|            ::|..::..|......|.....|..::.||
pombe  1013 SKRELPATPSWTRDSSLIKETTNLNLDSDKKFVRETYTSSNQTNEPDVYDKPS 1065

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Khc-73	NP_001261000.1	KISc_KIF1A_KIF1B	4..359	CDD:276816	137/380 (36%)
		KISc	6..359	CDD:214526	137/380 (36%)
		Kinesin_assoc	356..468	CDD:292801	26/118 (22%)
		FHA	446..546	CDD:238017	12/99 (12%)
		KIF1B	741..786	CDD:289208	10/44 (23%)
		DUF3694	<1196..1252	CDD:289256
		CAP_GLY	1786..1850	CDD:279625
cut7	NP_594527.1	KISc_BimC_Eg5	70..429	CDD:276815	137/381 (36%)
		KISc	72..428	CDD:214526	137/380 (36%)
		SbcC	<398..>966	CDD:223496	156/770 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910