Protein Alignment Pgant1 and GALNT4

DIOPT Version :9

• Sequence 1: NP_611043.1
• Gene: Pgant1 / 36717
• FlyBaseID: FBgn0034025
• Length: 601
• Species: Drosophila melanogaster
• Sequence 2: NP_003765.2
• Gene: GALNT4 / 8693
• HGNCID: 4126
• Length: 578
• Species: Homo sapiens
• Alignment Length: 609
• Identity: 235/609 - (38%)
• Similarity: 332/609 - (54%)
• Gaps: 65/609 - (10%)

  Fly    12 LIIFILVALCFI--LYSKVQQNGSPEEPPVAPLVRAAALRGHGRERFEAYSDSENEIARPATQSP 74
            |:.|:.||..|:  |.|....:..           |...|..|..|......:..:::||..:.|
Human    14 LLAFLTVAYIFVELLVSTFHASAG-----------AGRARELGSRRLSDLQKNTEDLSRPLYKKP 67

  Fly    75 YEQIIQLDLQKQKVGLGEQGVA--VHLSGAAKERGDEIYKKIALNEELSEQLTYNRSVGDHRNPL 137
                     ......|||.|.|  :.|:....::.:|:.::.|:|..||::::.:|.:.|.|...
Human    68 ---------PADSRALGEWGKASKLQLNEDELKQQEELIERYAINIYLSDRISLHRHIEDKRMYE 123

  Fly   138 CAKQRFDSDSLPTASVVIIFFNEPYSVLLRTVHSTLSTCNEKALKEIILVDDGSDNVELGAKLDY 202
            |..|:|:..:|||.||:|.|:||.:|.||||:||.|.|.....|||||||||.||.|.|..:|:.
Human   124 CKSQKFNYRTLPTTSVIIAFYNEAWSTLLRTIHSVLETSPAVLLKEIILVDDLSDRVYLKTQLET 188

  Fly   203 YVRTRIPSGKVTILRLKNRLGLIRARLAGARIATGDVLIFLDAHCEGNIGWCEPLLQRIKESRTS 267
            |:..   ..:|.::|...|.||:||||.||..||||||.|||.|||.|.||.||||:||....|:
Human   189 YISN---LDRVRLIRTNKREGLVRARLIGATFATGDVLTFLDCHCECNSGWLEPLLERIGRDETA 250

  Fly   268 VLVPIIDVIDANDFQYSTNGYKSF---QVGGFQWNGHFDWINLPEREKQRQRRECKQEREICPAY 329
            |:.|:||.||.|.|::    |...   .:|||.|...|.|.::|::|:.|      :...|.|..
Human   251 VVCPVIDTIDWNTFEF----YMQIGEPMIGGFDWRLTFQWHSVPKQERDR------RISRIDPIR 305

  Fly   330 SPTMAGGLFAIDRRYFWEVGSYDEQMDGWGGENLEMSFRIWQCGGTIETIPCSRVGHIFRDFHPY 394
            ||||||||||:.::||..:|:||..|:.|||||||:|||:|||||.:|..|||.|||:|....||
Human   306 SPTMAGGLFAVSKKYFQYLGTYDTGMEVWGGENLELSFRVWQCGGKLEIHPCSHVGHVFPKRAPY 370

  Fly   395 KFPNDRDTHGINTARMALVWMDEYINIFFLNRPDLKFHADIGDVTHRVMLRKKLRCKSFEWYLKN 459
            ..||...    ||||.|.||||||...|:...|..:..| .||::.|.:||::||||||:|||||
Human   371 ARPNFLQ----NTARAAEVWMDEYKEHFYNRNPPARKEA-YGDISERKLLRERLRCKSFDWYLKN 430

  Fly   460 IYPEKFVPTKDVQGW-GKVHAVN-SNICLD-DLLQNNEKPYNAGLYPC-GKVLQKSQLFSFTNTN 520
            ::|...|| :|..|| |.:.:.. |:.||| :...||....|..|:.| |:  ..:|.|.:|:..
Human   431 VFPNLHVP-EDRPGWHGAIRSRGISSECLDYNSPDNNPTGANLSLFGCHGQ--GGNQFFEYTSNK 492

  Fly   521 VLR-NELS--CATVQHSESPPYRVVMVPCMENDEF----NEQWRY-EHQHIIHSNTGMCLD-HQG 576
            .:| |.::  ||.|...::   .|.|..| ..|.|    |..|.: |...|.|.::|:||. ::.
Human   493 EIRFNSVTELCAEVPEQKN---YVGMQNC-PKDGFPVPANIIWHFKEDGTIFHPHSGLCLSAYRT 553

  Fly   577 LKSLDDAQVAPCDPHSESQRWTIE 600
            .:...|.|:..||...::|.|:.|
Human   554 PEGRPDVQMRTCDALDKNQIWSFE 577

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pgant1	NP_611043.1	WcaA	147..426	CDD:223539	141/281 (50%)
		pp-GalNAc-T	152..461	CDD:133004	156/311 (50%)
		Ricin_B_lectin	474..597	CDD:279046	38/135 (28%)
		RICIN	481..599	CDD:238092	37/129 (29%)
GALNT4	NP_003765.2	Catalytic subdomain A	134..243		63/111 (57%)
		pp-GalNAc-T	138..432	CDD:133004	156/311 (50%)
		Catalytic subdomain B	303..365		39/61 (64%)
		Ricin_B_lectin	446..574	CDD:395527	37/133 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3736
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D606683at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.820