DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Pgant1 and galnt9

DIOPT Version :9

Sequence 1:	NP_611043.1	Gene:	Pgant1 / 36717	FlyBaseID:	FBgn0034025	Length:	601	Species:	Drosophila melanogaster
Sequence 2:	XP_001338018.1	Gene:	galnt9 / 797549	ZFINID:	ZDB-GENE-060526-21	Length:	604	Species:	Danio rerio

Alignment Length:	653	Identity:	219/653 - (33%)
Similarity:	318/653 - (48%)	Gaps:	133/653 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    12 LIIFILVALCFILYSKVQQNGSPEEPPVAPLVRAAALRGHGR--------------ERFEAYSD- 61
            :::|:.:.| |.:|.::|...  ||  :..:.|.:..|..||              :|.|...|
Zfish    15 ILVFVGIIL-FSVYCRIQDRS--EE--LVQIGRLSDQRLRGRNAKVTNSMDRQSILKRLERLEDV 74

  Fly    62 ---SENEIARPATQSPYEQIIQLDLQKQKVGLGEQGVAVHLSGAAKERGDEIYKKIALNEELSEQ 123
               ..|.:|:|           :.|.:...|||:.|.|..|...::|. :..:::...|.:||::
Zfish    75 VYNQLNGLAKP-----------MGLVEGPGGLGQGGAAATLGEDSRET-EGRFEEYGYNAQLSDR 127

  Fly   124 LTYNRSVGDHRNPLCAKQRFDSDSLPTASVVIIFFNEPYSVLLRTVHSTLSTCNEKALKEIILVD 188
            ::.:|::.|:|...| ||...||.||..|||.||.||..||:||:|||.::......||||||||
Zfish   128 ISLDRNIPDYRPKKC-KQLTYSDDLPQISVVFIFVNEALSVILRSVHSMVNHTPAHLLKEIILVD 191

  Fly   189 DGSDNVELGAKLDYYVRTRIPSGKVTILRLKNRLGLIRARLAGARIATGDVLIFLDAHCEGNIGW 253
            |.||:|||...||:||..|.| |.|.|:|...|.||||||:.|...||..|:.|.|||.|.|..|
Zfish   192 DNSDSVELKFNLDHYVNKRYP-GLVKIVRNSKREGLIRARIHGWNAATAPVVGFFDAHVEFNTAW 255

  Fly   254 CEPLLQRIKESRTSVLVPIIDVIDANDF---QYSTNGYKSFQVGGFQWNGHF--------DWINL 307
            .||:|.|:||..|.:::|.||.|..|.|   ||:...:      |:.| |.:        ||::.
Zfish   256 AEPILTRVKEDHTRIILPAIDNIKYNTFEVQQYANAAH------GYNW-GLWCMYIIPPQDWLDR 313

  Fly   308 PEREKQRQRRECKQEREICPAYSPTMAGGLFAIDRRYFWEVGSYDEQMDGWGGENLEMSFRIWQC 372
            .:              |..|..:|.|.|..|.:||.||.|:|..|..|:.:||||:|:..|:|||
Zfish   314 GD--------------ETAPIRTPAMIGCSFVVDREYFGEIGLLDPGMEVYGGENIELGMRVWQC 364

  Fly   373 GGTIETIPCSRVGHIFRDFHPYKFPNDRDTHG-INTARMALVWMDEYINIFF------LNRPDLK 430
            ||::|.:||:||.||.|...||.  ||.|.:. .|..|.|.|||||:.:..:      :|.|.:
Zfish   365 GGSMEVLPCARVAHIERTKKPYN--NDIDYYAKRNALRAAEVWMDEFKSHVYMAWNIPMNNPGV- 426

  Fly   431 FHADIGDVTHRVMLRKKLRCKSFEWYLKNIYPEKFVPTKDVQGWGKV-HAVNSNICLDDLLQNNE 494
               |.|||:.||.||||:.||||.|||:::|||..:....:. :|:| ::..|..|||   |.:|
Zfish   427 ---DFGDVSERVALRKKMNCKSFRWYLEHVYPEMRIYNNTIT-YGEVRNSKASGYCLD---QGSE 484

  Fly   495 KPYNAGLYPCGKVLQKSQLFSFTNTNVLRNELSCATVQHSESPPYRVVMVP---CMEND------ 550
            :...|.||||..:  .|||..:|...:|:           ..|......:|   |:.:|
Zfish   485 EDERAILYPCHGM--SSQLARYTTEGLLQ-----------LGPLGSTTFLPDTKCLVDDGRGRTP 536

  Fly   551 ----------EFNEQWRY-EHQHIIHSNTGMCLDHQGLKSLDDAQ------VAPCDPHSESQRWT 598
                      .....|.: ::..||..:||.||:.:..|   ||.      |..|    ..|:|.
Zfish   537 SLKKCDSVTRSSQRLWDFTQNGPIISRDTGRCLEVEMSK---DANFGLRLVVQRC----SGQKWM 594

  Fly   599 IEH 601
            |.:
Zfish   595 IRN 597

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Pgant1	NP_611043.1	WcaA	147..426	CDD:223539	124/296 (42%)
		pp-GalNAc-T	152..461	CDD:133004	141/326 (43%)
		Ricin_B_lectin	474..597	CDD:279046	35/149 (23%)
		RICIN	481..599	CDD:238092	34/143 (24%)
galnt9	XP_001338018.1	pp-GalNAc-T	155..454	CDD:133004	141/326 (43%)
		Ricin_B_lectin	465..593	CDD:279046	35/151 (23%)
		RICIN	467..595	CDD:238092	36/150 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3736
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.810