Protein Alignment Pgant1 and GALNT14

DIOPT Version :10

• Sequence 1: NP_611043.1
• Gene: Pgant1 / 36717
• FlyBaseID: FBgn0034025
• Length: 601
• Species: Drosophila melanogaster
• Sequence 2: NP_001240755.1
• Gene: GALNT14 / 79623
• HGNCID: 22946
• Length: 557
• Species: Homo sapiens
• Alignment Length: 460
• Identity: 194/460 - (42%)
• Similarity: 263/460 - (57%)
• Gaps: 32/460 - (6%)

  Fly   148 LPTASVVIIFFNEPYSVLLRTVHSTLSTCNEKALKEIILVDDGSDNVELGAKLDYYVRTRIPSGK 212
            ||..|::|.|.||..|.||||:.|.|:......::|||||||.|::.:     |.....::|  |
Human   115 LPPTSIIITFHNEARSTLLRTIRSVLNRTPTHLIREIILVDDFSNDPD-----DCKQLIKLP--K 172

  Fly   213 VTILRLKNRLGLIRARLAGARIATGDVLIFLDAHCEGNIGWCEPLLQRIKESRTSVLVPIIDVID 277
            |..||...|.||:|:|:.||.||.|..|.|||:|||.|..|.:|||.|:||..|.|:.|:||:|:
Human   173 VKCLRNNERQGLVRSRIRGADIAQGTTLTFLDSHCEVNRDWLQPLLHRVKEDYTRVVCPVIDIIN 237

  Fly   278 ANDFQYSTNGYKSFQVGGFQWNGHFDWINL-PEREKQRQRRECKQEREICPAYSPTMAGGLFAID 341
            .:.|.|..:.  |...|||.|:.||.|..| ||   |:.||....|    |..:|.:|||||.||
Human   238 LDTFTYIESA--SELRGGFDWSLHFQWEQLSPE---QKARRLDPTE----PIRTPIIAGGLFVID 293

  Fly   342 RRYFWEVGSYDEQMDGWGGENLEMSFRIWQCGGTIETIPCSRVGHIFRDFHPYKFPN-DRDTHGI 405
            :.:|..:|.||..||.|||||.|:|||:|.|||::|.:|||||||:||..|||.||: :.:|:..
Human   294 KAWFDYLGKYDMDMDIWGGENFEISFRVWMCGGSLEIVPCSRVGHVFRKKHPYVFPDGNANTYIK 358

  Fly   406 NTARMALVWMDEYINIFFLNRPDLKFHADIGDVTHRVMLRKKLRCKSFEWYLKNIYPEKFVPTKD 470
            ||.|.|.||||||...::..|| .......|:|..|:.|||.|||:||:|||:|||||..:|.:.
Human   359 NTKRTAEVWMDEYKQYYYAARP-FALERPFGNVESRLDLRKNLRCQSFKWYLENIYPELSIPKES 422

  Fly   471 VQGWGKVHAVNSNICLDDLLQNNEKPYNAGLYPCGKVL---QKSQLFSFTNT-NVLRNELSCATV 531
            ....|.:.  ....||:...|||::..|..|.||.||.   .|||:::||.| .:|:.||..:.:
Human   423 SIQKGNIR--QRQKCLESQRQNNQETPNLKLSPCAKVKGEDAKSQVWAFTYTQQILQEELCLSVI 485

  Fly   532 QHSESPPYRVVMVPCMENDEFNEQWRYEHQHIIHSNTGMCLD----HQGLKSLDDAQVAPCDPHS 592
            ......|  ||:|.|...|: .:||.....||.|..:.:|||    ..|.::..:..|.||:...
Human   486 TLFPGAP--VVLVLCKNGDD-RQQWTKTGSHIEHIASHLCLDTDMFGDGTENGKEIVVNPCESSL 547

  Fly   593 ESQRW 597
            .||.|
Human   548 MSQHW 552

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pgant1	NP_611043.1	pp-GalNAc-T	152..461	CDD:133004	145/310 (47%)
		beta-trefoil_Ricin_Pgant1-like	468..601	CDD:467337	42/138 (30%)
GALNT14	NP_001240755.1	pp-GalNAc-T	119..413	CDD:133004	145/310 (47%)
		beta-trefoil_Ricin-like	418..557	CDD:483949	43/140 (31%)