DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Pgant1 and Galnt15

DIOPT Version :9

Sequence 1:	NP_611043.1	Gene:	Pgant1 / 36717	FlyBaseID:	FBgn0034025	Length:	601	Species:	Drosophila melanogaster
Sequence 2:	XP_006519762.1	Gene:	Galnt15 / 78754	MGIID:	1926004	Length:	652	Species:	Mus musculus

Alignment Length:	670	Identity:	203/670 - (30%)
Similarity:	306/670 - (45%)	Gaps:	96/670 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MLPRFRSFYGK-----LIIFILVALCFILYSKVQQNGSPEEPPVAPLVRAAALRGHGRE---RFE 57
            ||||.|...|:     |::|:.:....::...:.    |..|.:...|.|.|.: |..:   |.:
Mouse     1 MLPRKRPRSGRSRLQFLLLFLTLGCVLMMVILLH----PPPPTLHQAVTAQASK-HSPDTGYRLD 60

  Fly    58 AYSDSENEIARPATQSPYEQIIQ-----LDLQKQKVGLG--------------EQG--------- 94
             :.||:..:....|:.....::.     :.||:.::.:.              .||
Mouse    61 -FGDSQEWVLEAETEGDEYSLLDGLPSFISLQEDQLLVAVASPRARRSQSQGRRQGSYQFIKHRS 124

  Fly    95 -----VAVHLSGAAKERGDEIYKKI--------ALNEELSEQLTYNRSVGDHRNPLCAKQRFDSD 146
                 .|:......:|.|:|..:.:        .||:.||.:|...|.:.:.|:|||.:|. .:.
Mouse   125 RRWDEEALEKDWRTEEDGEESEEVLTPLGPDSDGLNKPLSARLPLRRVLPEVRHPLCLQQH-PTS 188

  Fly   147 SLPTASVVIIFFNEPYSVLLRTVHSTLSTCNEKALKEIILVDDGSDNVELGAKLDYYVRTRIPSG 211
            .||||||::.|.:|.:..|||||||.|.|.....|:|||||||.|....|.:.|..|| .|:.:
Mouse   189 GLPTASVILCFHDEAWPTLLRTVHSILDTAPRALLQEIILVDDLSQQELLKSALSEYV-ARLEA- 251

  Fly   212 KVTILRLKNRLGLIRARLAGARIATGDVLIFLDAHCEGNIGWCEPLLQRIKESRTSVLVPIIDVI 276
             |.:||...|||.|.||:.||..||||||:|:|||||.:.||.||||.||.:.|:.|:.|:||||
Mouse   252 -VKLLRSNRRLGTIGARMLGATRATGDVLVFMDAHCECHPGWLEPLLSRIADDRSRVVSPVIDVI 315

  Fly   277 DANDFQYSTNGYKSFQVGGFQWNGHFDWINLPEREKQRQRRECKQEREICPAYSPTMAGGLFAID 341
            |....|||.:   ....|...|...|.|..|.|:|::      .....|.|..||.:...:.|:|
Mouse   316 DWKTLQYSAS---KLHRGTLDWKLDFRWKPLGEQEQK------ALPSPISPVRSPVVPREVVAVD 371

  Fly   342 RRYFWEVGSYDEQMDGWGGENLEMSFRIWQCGGTIETIPCSRVGHIFRDFHPYKFPNDRDTHGIN 406
            |.||...|:||..:.....|||||||:.|.|||::|.:||||||||:|.......| |.:....|
Mouse   372 RHYFQNTGAYDPLLSLGDSENLEMSFKAWLCGGSVEILPCSRVGHIYRSQDASSRP-DPEVALKN 435

  Fly   407 TARMALVWMDEYINIFFLNRPDLKFHADIG--DVTHRVMLRKKLRCKSFEWYLKNIYPEKFVPTK 469
            ...:|..|:..:...|:.:.|:....:.:.  |.|.|:.|:::|.|::|.|:|.|:|||.:....
Mouse   436 KIIIAETWLSSFKETFYRHIPEAFTLSKVAKPDCTERLKLQRRLGCRTFHWFLANVYPELYPSDH 500

  Fly   470 DVQGWGKVHAVNSNICLDDLLQNNEKPYNAGLYPC--GKVLQKSQLFSFTNTNVLRN-------- 524
            ..:..||:|.....:|.|.....:.......|.||  .:..|.:.|...|.|...:|
Mouse   501 RPRFSGKLHNTGFGLCADCQADGDILGCPMTLAPCSNNRQQQGTLLAMLTATPSAQNLEHTGRKE 565

  Fly   525 ------ELSCATVQHSESPPYRVVMVPCMENDEFNEQWRYEHQH---IIHSNTGMCLDHQGLKSL 580
                  :..|..|:..     ||::..|.|......|..::.|.   |||..:|.|::.....|.
Mouse   566 ILFGGPQRLCFDVRGG-----RVILQNCTEEGPAIHQQHWDFQEDGMIIHVLSGKCMEAGVQPSN 625

  Fly   581 DDAQVAPCDPHSESQRWTIE 600
            .|..:..||..: ||.|..:
Mouse   626 KDLYLRQCDGKT-SQLWRFD 644

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Pgant1	NP_611043.1	WcaA	147..426	CDD:223539	119/278 (43%)
		pp-GalNAc-T	152..461	CDD:133004	126/310 (41%)
		Ricin_B_lectin	474..597	CDD:279046	32/141 (23%)
		RICIN	481..599	CDD:238092	30/136 (22%)
Galnt15	XP_006519762.1	pp-GalNAc-T	194..492	CDD:133004	126/310 (41%)
Galnt15	XP_006519762.1	Ricin_B_lectin	504..641	CDD:366226	32/142 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3736
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D606683at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.820