DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Pgant1 and galnt14

DIOPT Version :9

Sequence 1:	NP_611043.1	Gene:	Pgant1 / 36717	FlyBaseID:	FBgn0034025	Length:	601	Species:	Drosophila melanogaster
Sequence 2:	NP_001072369.1	Gene:	galnt14 / 779822	XenbaseID:	XB-GENE-992201	Length:	555	Species:	Xenopus tropicalis

Alignment Length:	554	Identity:	201/554 - (36%)
Similarity:	303/554 - (54%)	Gaps:	42/554 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly    52 GRERFEAYSDSENEIARPATQSPYEQIIQLDLQKQKVGLGEQGVAVHLSGAAKERGDEIYKKIAL 116
            ||.:.|| .:||.:.|:.......:...|.|.::            :|:......|::.|:..|.
Frog    28 GRRKLEA-EESEGDPAKEGDVDWDDLWDQFDERR------------YLNAQKWRPGEDPYRLYAF 79

  Fly   117 NEELSEQLTYNRSVGDHRNPLCAKQRFDSDSLPTASVVIIFFNEPYSVLLRTVHSTLSTCNEKAL 181
            |:..||::..:|::.|.|:..|.:..:.|| ||..||:|.|.||..|.||||:.|.|:......:
Frog    80 NQRESERIPSDRAIKDTRHYRCTELHYQSD-LPPTSVIITFHNEARSTLLRTIRSVLNRTPMHLI 143

  Fly   182 KEIILVDDGSDNVELGAKLDYYVRTRIPSGKVTILRLKNR-LGLIRARLAGARIATGDVLIFLDA 245
            .||:||||.|||::     |..:.:::|  ||..||.:.| .||||:|:.||.:|...||.|||:
Frog   144 HEILLVDDFSDNLD-----DCRLLSKLP--KVRCLRNEQREAGLIRSRVRGAGVAQAAVLTFLDS 201

  Fly   246 HCEGNIGWCEPLLQRIKESRTSVLVPIIDVIDANDFQYSTNGYKSFQVGGFQWNGHFDWINLPER 310
            |||.|..|..|||.||||..|.|:.|:||:|:.:.|.|.  ...|...|||.|:.||.|..|...
Frog   202 HCEVNKDWLPPLLHRIKEDPTRVVSPVIDIINLDTFAYI--AASSDLRGGFDWSLHFKWEQLSAE 264

  Fly   311 EKQRQRRECKQEREICPAYSPTMAGGLFAIDRRYFWEVGSYDEQMDGWGGENLEMSFRIWQCGGT 375
            :|.::....:      |..:|.:|||||.|::.:|..:|.||..||.|||||.|:|||:|.|||:
Frog   265 QKAKRLDPTE------PIKTPVIAGGLFVIEKSWFNHLGKYDTAMDIWGGENFEISFRVWMCGGS 323

  Fly   376 IETIPCSRVGHIFRDFHPYKFP-NDRDTHGINTARMALVWMDEYINIFFLNRPDLKFHADIGDVT 439
            :|.||||||||:||..|||.|| .:.:|:..||.|.|.|||||:.|.::..||..: ....||:.
Frog   324 LEIIPCSRVGHVFRKKHPYVFPEGNANTYIKNTKRTAEVWMDEFKNHYYAARPAAQ-GRPYGDIQ 387

  Fly   440 HRVMLRKKLRCKSFEWYLKNIYPEKFVPTKDVQGWGKVHAVNSNICLDDLLQNNEKPYNAGLYPC 504
            .|:.||:.|:|:||:|||:|:|||..:|.:.:...|.:.  ....|::.......:|.:..|.||
Frog   388 KRLSLRRTLKCRSFKWYLENVYPELQIPAESLSKSGIIR--QRQRCIESQKTEGPEPPSLNLVPC 450

  Fly   505 GK---VLQKSQLFSFTNTNVLRNELSCATVQHSESPPYRVVMVPCMENDEFNEQWRYEHQHIIHS 566
            ..   |..:||.:.:|....:.....|.:| |:..|..:||::||.|.|. .::|.....||.|.
Frog   451 SSLKGVSPQSQEWVYTQVQQISQGPLCMSV-HTLFPGTQVVLLPCREGDG-KQRWSKVGSHIEHM 513

  Fly   567 NTGMCLDHQGLKSLDDAQ---VAPCDPHSESQRW 597
            .:..|||...:...::::   :.||:..:.:|||
Frog   514 ASRFCLDTDIIGDTEESREIVINPCETTAITQRW 547

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Pgant1	NP_611043.1	WcaA	147..426	CDD:223539	128/280 (46%)
		pp-GalNAc-T	152..461	CDD:133004	141/310 (45%)
		Ricin_B_lectin	474..597	CDD:279046	30/128 (23%)
		RICIN	481..599	CDD:238092	31/123 (25%)
galnt14	NP_001072369.1	Abhydrolase	1..>78	CDD:304388	12/62 (19%)
		Glyco_tranf_2_3	111..338	CDD:290369	110/241 (46%)
		pp-GalNAc-T	114..409	CDD:133004	141/310 (45%)
		Ricin_B_lectin	422..547	CDD:279046	30/128 (23%)
		RICIN	423..549	CDD:238092	32/129 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D606683at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010