Protein Alignment Pgant1 and Galnt14

DIOPT Version :10

• Sequence 1: NP_611043.1
• Gene: Pgant1 / 36717
• FlyBaseID: FBgn0034025
• Length: 601
• Species: Drosophila melanogaster
• Sequence 2: NP_082140.2
• Gene: Galnt14 / 71685
• MGIID: 1918935
• Length: 550
• Species: Mus musculus
• Alignment Length: 541
• Identity: 211/541 - (39%)
• Similarity: 289/541 - (53%)
• Gaps: 40/541 - (7%)

  Fly    69 PATQSPYEQIIQLDLQKQKVGLGEQGVAVHLSGAAKER-GDEIYKKIALNEELSEQLTYNRSVGD 132
            |..|:|.......|      .|.||........|.|.| ||:.||..|.|:..||:::.||:|.|
Mouse    37 PEVQTPKPSDADWD------DLWEQFDERRYLNAKKWRVGDDPYKLYAFNQRESERISSNRAVPD 95

  Fly   133 HRNPLCAKQRFDSDSLPTASVVIIFFNEPYSVLLRTVHSTLSTCNEKALKEIILVDDGSDNVELG 197
            .|:..|:...:.:| ||..|::|.|.||..|.||||:.|.|:......::|||||||.|::.|
Mouse    96 TRHKRCSLLVYCTD-LPPTSIIITFHNEARSTLLRTIRSVLNRTPMHLIQEIILVDDFSNDPE-- 157

  Fly   198 AKLDYYVRTRIPSGKVTILRLKNRLGLIRARLAGARIATGDVLIFLDAHCEGNIGWCEPLLQRIK 262
               |.....::|  ||..||...|.||:|:|:.||.||.|..|.|||:|||.|..|.:|||.|:|
Mouse   158 ---DCKQLIKLP--KVKCLRNNERQGLVRSRMRGADIAQGTTLTFLDSHCEVNRDWLQPLLHRVK 217

  Fly   263 ESRTSVLVPIIDVIDANDFQYSTNGYKSFQVGGFQWNGHFDWINLPEREKQRQRRECKQEREICP 327
            |..|.|:.|:||:|:.:.|.|..:.  |...|||.|:.||.|..|...:|..:....:      |
Mouse   218 EDYTRVVCPVIDIINLDTFNYIESA--SELRGGFDWSLHFQWEQLSLEQKALRLDPTE------P 274

  Fly   328 AYSPTMAGGLFAIDRRYFWEVGSYDEQMDGWGGENLEMSFRIWQCGGTIETIPCSRVGHIFRDFH 392
            ..:|.:|||||.||:.:|..:|.||..||.|||||.|:|||:|.|||.:|.||||||||:||..|
Mouse   275 IRTPIIAGGLFVIDKAWFDYLGKYDVDMDIWGGENFEISFRVWMCGGGLEIIPCSRVGHVFRKKH 339

  Fly   393 PYKFPN-DRDTHGINTARMALVWMDEYINIFFLNRPDLKFHADIGDVTHRVMLRKKLRCKSFEWY 456
            ||.||: :.:|:..||.|.|.||||||...::..|| .......|::.:|:.|||.|.|::|:||
Mouse   340 PYVFPDGNANTYIKNTKRTAEVWMDEYKQYYYAARP-FALERPFGNIENRLNLRKNLHCQTFKWY 403

  Fly   457 LKNIYPEKFVPTKDVQGWGKVHAVNSNICLDDLLQNNEKPYNAGLYPCGKVL---QKSQLFSFTN 518
            |:|:|||..||.......|.:.  ....||:.  |..:|.....|.||.||.   .|||:::||.
Mouse   404 LENVYPELRVPPDSSIQKGNIR--QRQKCLES--QKQKKQEILRLSPCAKVKGDGAKSQVWAFTY 464

  Fly   519 T-NVLRNELSCATVQHSESPPYRVVMVPCMENDEFNEQWRYEHQHIIHSNTGMCLDHQGL-KSLD 581
            | .:::.||..:.|......|  ||:..|...|| .:.|......|.|..:.:|||.... .|.:
Mouse   465 TQQIIQEELCLSVVTLFPGAP--VVLALCKNGDE-RQLWTKTGARIEHIASHLCLDTDMFGDSTE 526

  Fly   582 DAQ---VAPCDPHSESQRWTI 599
            |.:   |.||:....||.|.|
Mouse   527 DGKEVVVNPCESSLMSQHWDI 547

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pgant1	NP_611043.1	pp-GalNAc-T	152..461	CDD:133004	139/309 (45%)
		beta-trefoil_Ricin_Pgant1-like	468..601	CDD:467337	40/140 (29%)
Galnt14	NP_082140.2	Catalytic subdomain A	110..215		51/111 (46%)
		pp-GalNAc-T	114..408	CDD:133004	139/309 (45%)
		Catalytic subdomain B	274..336		37/61 (61%)
		beta-trefoil_Ricin-like	413..550	CDD:483949	42/142 (30%)