DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Pgant1 and Galntl5

DIOPT Version :9

Sequence 1:	NP_611043.1	Gene:	Pgant1 / 36717	FlyBaseID:	FBgn0034025	Length:	601	Species:	Drosophila melanogaster
Sequence 2:	NP_080725.2	Gene:	Galntl5 / 67909	MGIID:	1915159	Length:	431	Species:	Mus musculus

Alignment Length:	352	Identity:	152/352 - (43%)
Similarity:	209/352 - (59%)	Gaps:	14/352 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly   112 KKIALNEELSEQLTYNRSVGDHRNPLCAKQRFDSDSLPTASVVIIFFNEPYSVLLRTVHSTLSTC 176
            ::..||..:|.:|...|.|.|.|:.:|.::.:.. :|||||::|.|:||.::.|||.|.|.::..
Mouse    79 RRYGLNAIMSRRLGIEREVPDSRDKICQQKHYPF-NLPTASIIICFYNEEFNTLLRAVSSVVNLS 142

  Fly   177 NEKALKEIILVDDGSDNVELGAKLDYYVRTRIPSGKVTILRLKNRLGLIRARLAGARIATGDVLI 241
            .:..|:|||||||.|:..:|..|||||:  .|..|||.::|.|.|.||||:::.||..|:||:|:
Mouse   143 PQHLLEEIILVDDMSEFDDLKDKLDYYL--EIFRGKVKLIRNKKREGLIRSKMIGASRASGDILV 205

  Fly   242 FLDAHCEGNIGWCEPLLQRIKESRTSVLVPIIDVIDANDFQYSTNGYKSFQVGGFQWNGHFDWIN 306
            |||:|||.|..|.||||..|.:....|:.||||||:.....|..   .....|.|.||.:..|.|
Mouse   206 FLDSHCEVNRVWLEPLLHAIAKDHKMVVCPIIDVINELTLDYMA---APIVRGAFDWNLNLRWDN 267

  Fly   307 LPEREKQRQRRECKQEREICPAYSPTMAGGLFAIDRRYFWEVGSYDEQMDGWGGENLEMSFRIWQ 371
            :...|..      ..|....|..||.|.||:|||:|.||.|:|.||..||..||||:|:|.|||.
Mouse   268 VFAYELD------GPEGPSTPIRSPAMTGGIFAINRHYFNELGQYDNGMDICGGENVELSLRIWM 326

  Fly   372 CGGTIETIPCSRVGHIFRDFHPYKFPNDRDTHGINTARMALVWMDEYINIFFLNRPDLKFHADIG 436
            |||.:..:||||||:..:....::..| :.....|..|:..||:|||...|||.||.|.: ...|
Mouse   327 CGGQLFILPCSRVGYNSKALSQHRRAN-QSALSRNLLRVVHVWLDEYKGNFFLQRPSLTY-VSCG 389

  Fly   437 DVTHRVMLRKKLRCKSFEWYLKNIYPE 463
            :::.||.|||:|.||||:|||.||:||
Mouse   390 NISERVELRKRLGCKSFQWYLDNIFPE 416

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Pgant1	NP_611043.1	WcaA	147..426	CDD:223539	122/278 (44%)
		pp-GalNAc-T	152..461	CDD:133004	136/308 (44%)
		Ricin_B_lectin	474..597	CDD:279046
		RICIN	481..599	CDD:238092
Galntl5	NP_080725.2	Catalytic subdomain A	114..224		58/111 (52%)
		pp-GalNAc-T	118..414	CDD:133004	136/308 (44%)
		Glyco_tranf_2_2	118..380	CDD:287123	118/273 (43%)
		Catalytic subdomain B	282..344		36/61 (59%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3736
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D606683at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.820