Protein Alignment Pgant1 and GALNT16

DIOPT Version :9

• Sequence 1: NP_611043.1
• Gene: Pgant1 / 36717
• FlyBaseID: FBgn0034025
• Length: 601
• Species: Drosophila melanogaster
• Sequence 2: NP_001161840.1
• Gene: GALNT16 / 57452
• HGNCID: 23233
• Length: 558
• Species: Homo sapiens
• Alignment Length: 573
• Identity: 217/573 - (37%)
• Similarity: 306/573 - (53%)
• Gaps: 68/573 - (11%)

  Fly    45 AAALRGHGRERFEAYSDSENE---IARPATQSPYEQIIQLDLQKQKVGLGEQGVAVHLSGAAKER 106
            ||:..|.|.:|....|:...|   |....|.:|.:            |..|:   .:||....:.
Human    32 AASSGGRGAQRAGRRSEQLREDRTIPLIVTGTPSK------------GFDEK---AYLSAKQLKA 81

  Fly   107 GDEIYKKIALNEELSEQLTYNRSVGDHRNPLCAKQRFDSDSLPTASVVIIFFNEPYSVLLRTVHS 171
            |::.|::.|.|:..|::|:.:|.:.|.|:..|....:.|| ||..||:|.|.||..|.|||||.|
Human    82 GEDPYRQHAFNQLESDKLSPDRPIRDTRHYSCPSVSYSSD-LPATSVIITFHNEARSTLLRTVKS 145

  Fly   172 TLSTCNEKALKEIILVDDGSDNVELGAKLDYYVRTRIPSGKVTILRLKNRLGLIRARLAGARIAT 236
            .|:......::|||||||.|.:.|     |..:.||||  ||..||...|.||||:|:.||.:|.
Human   146 VLNRTPANLIQEIILVDDFSSDPE-----DCLLLTRIP--KVKCLRNDRREGLIRSRVRGADVAA 203

  Fly   237 GDVLIFLDAHCEGNIGWCEPLLQRIKESRTSVLVPIIDVIDANDFQYSTNGYKSFQV-GGFQWNG 300
            ..||.|||:|||.|..|..|:|||:||..|.|:.||||||..::|.|..   .|..: |||.|:.
Human   204 ATVLTFLDSHCEVNTEWLPPMLQRVKEDHTRVVSPIIDVISLDNFAYLA---ASADLRGGFDWSL 265

  Fly   301 HFDWINLPEREKQRQRRECKQEREICPAYSPTMAGGLFAIDRRYFWEVGSYDEQMDGWGGENLEM 365
            ||.|..:|..:|..:....:      |..:|.:|||:|.||:.:|..:|.||.|||.|||||.|:
Human   266 HFKWEQIPLEQKMTRTDPTR------PIRTPVIAGGIFVIDKSWFNHLGKYDAQMDIWGGENFEL 324

  Fly   366 SFRIWQCGGTIETIPCSRVGHIFRDFHPYKFPNDRD-THGINTARMALVWMDEYINIFFLNRPDL 429
            |||:|.|||::|.:|||||||:||..|||.||.... |:..||.|.|.||||||...::..||..
Human   325 SFRVWMCGGSLEIVPCSRVGHVFRKRHPYNFPEGNALTYIRNTKRTAEVWMDEYKQYYYEARPSA 389

  Fly   430 KFHADIGDVTHRVMLRKKLRCKSFEWYLKNIYPEKFVPTKDV------QGWGKVHAVNSNICLDD 488
            ...| .|.|..|:..|||:.||||.|||:|:|||..||.|:.      ||      ||   ||:.
Human   390 IGKA-FGSVATRIEQRKKMNCKSFRWYLENVYPELTVPVKEALPGIIKQG------VN---CLES 444

  Fly   489 LLQNNEKPYNAGLYPC---GKVLQKSQLFSFTNTNVLRNELSC--ATVQHSESPPYRVVMVPCME 548
            ..||....:..|:..|   .|..|.:|.:.|:: ::::.:..|  ||.....||...|::..|..
Human   445 QGQNTAGDFLLGMGICRGSAKNPQPAQAWLFSD-HLIQQQGKCLAATSTLMSSPGSPVILQMCNP 508

  Fly   549 NDEFNEQWRYEHQHIIHSNTGMCLDHQGLKSLDDAQV--APCDPHSESQRWTI 599
            . |..::||.:...|.||.:|:||:.:      .||:  :.|...:::|:|.:
Human   509 R-EGKQKWRRKGSFIQHSVSGLCLETK------PAQLVTSKCQADAQAQQWQL 554

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pgant1	NP_611043.1	WcaA	147..426	CDD:223539	133/280 (48%)
		pp-GalNAc-T	152..461	CDD:133004	148/310 (48%)
		Ricin_B_lectin	474..597	CDD:279046	32/129 (25%)
		RICIN	481..599	CDD:238092	32/124 (26%)
GALNT16	NP_001161840.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	33..54		6/20 (30%)
		Catalytic subdomain A	122..227		55/111 (50%)
		pp-GalNAc-T	126..420	CDD:133004	148/310 (48%)
		Catalytic subdomain B	286..348		36/61 (59%)
		Ricin_B_lectin	441..543	CDD:395527	28/109 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3736
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D606683at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.820