DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Pgant1 and galnt17

DIOPT Version :9

Sequence 1:	NP_611043.1	Gene:	Pgant1 / 36717	FlyBaseID:	FBgn0034025	Length:	601	Species:	Drosophila melanogaster
Sequence 2:	XP_696189.5	Gene:	galnt17 / 567794	ZFINID:	ZDB-GENE-110419-5	Length:	617	Species:	Danio rerio

Alignment Length:	545	Identity:	188/545 - (34%)
Similarity:	284/545 - (52%)	Gaps:	75/545 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly    89 GLGEQGVAVHLSGAAKERGDEIYKKIALNEELSEQLTYNRSVGDHRNPLCAKQRFDSDSLPTASV 153
            |.|..|:...|:.|.::....:.:|...|..||::::.:||:.|:|...|.|..|..| ||..|:
Zfish   108 GRGRGGIPATLTPAEEKEAKFLREKYGYNAFLSDKISLDRSLPDYRPSKCKKAFFPRD-LPQISI 171

  Fly   154 VIIFFNEPYSVLLRTVHSTLSTCNEKALKEIILVDDGSDNVELGAKLDYYVRTRIPSGKVTILRL 218
            :.||.||..||:||:|||.::......|||||||||.||:|:|...|:.||..|.| |.:.|:|.
Zfish   172 IFIFVNEALSVILRSVHSAVNHTPAHLLKEIILVDDNSDDVQLKGPLEEYVNKRYP-GLIKIVRN 235

  Fly   219 KNRLGLIRARLAGARIATGDVLIFLDAHCEGNIGWCEPLLQRIKESRTSVLVPIIDVIDANDFQ- 282
            :.|.||||||:.|.::|||:|..|.|||.|....|.||:|.||||:...:::|.||.|....|:
Zfish   236 QKREGLIRARIEGWKVATGEVTGFFDAHVEFTPAWAEPVLSRIKENHKRIILPSIDNIKDETFEL 300

  Fly   283 --YSTNGYKSFQVGGFQWNGHFDWINLPEREKQRQRRECKQEREI-CPAYSPTMAGGLFAIDRRY 344
              |..:|:      |:.|.....:|:.|        ::...|.:. .|..:|.|.|..|.::|.|
Zfish   301 ERYENSGH------GYNWELWCMYISPP--------KQWWDEGDTSAPIRTPAMIGCSFVVNREY 351

  Fly   345 FWEVGSYDEQMDGWGGENLEMSFRIWQCGGTIETIPCSRVGHIFRDFHPY----KFPNDRDTHGI 405
            |.::|..|..||.:||||:|:..|:|.|||::|.:|||||.||.|...||    .|...|
Zfish   352 FGDLGLLDAGMDVYGGENIELGIRVWLCGGSMEVLPCSRVAHIARTKKPYHSNIAFHTRR----- 411

  Fly   406 NTARMALVWMDEYINIFFL--NRPDLKFHA-DIGDVTHRVMLRKKLRCKSFEWYLKNIYPEKFVP 467
            |..|:|.||||:|.:..:|  |.| :|.|. |.|||:.|:.|||:|:||||:|||.|||||....
Zfish   412 NALRVAEVWMDQYKSNVYLAWNLP-MKNHGIDYGDVSERLALRKRLQCKSFDWYLDNIYPEMRRY 475

  Fly   468 TKDVQGWGKVHAVN-SNICLDDLLQNNEKPYNAGLYPC-------GKVLQKSQLF--SFTNTNVL 522
            ...| .:|::...| :::|:|..::.|   :.|.|:||       |:..::..||  ...:|.
Zfish   476 NNTV-FYGEIRNTNVTHLCVDQGIKEN---HTATLHPCHGWGPQLGRYTKEGYLFLGPLGSTG-- 534

  Fly   523 RNELSCATVQHSESPPYRVVMVPCMENDEFNEQ-WRY-EHQHIIHSNTGMCLDHQGLKSLDDAQV 585
             .:..|.......|.|.   ::.|.:.....:: |.: :::.||...||.||           :|
Zfish   535 -EDTRCVVDDKISSYPQ---LLNCEKVSSVRQKTWHFAQNESIISRATGRCL-----------EV 584

  Fly   586 APCDPH---------SESQRWTIEH 601
            .|.:.:         ...|:|.|::
Zfish   585 VPANVYFGYALILRSCTGQKWNIKN 609

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Pgant1	NP_611043.1	WcaA	147..426	CDD:223539	116/288 (40%)
		pp-GalNAc-T	152..461	CDD:133004	135/319 (42%)
		Ricin_B_lectin	474..597	CDD:279046	27/143 (19%)
		RICIN	481..599	CDD:238092	27/138 (20%)
galnt17	XP_696189.5	pp-GalNAc-T	170..469	CDD:133004	135/319 (42%)
		Ricin_B_lectin	480..605	CDD:279046	27/144 (19%)
		RICIN	482..607	CDD:238092	28/144 (19%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3736
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.810