DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Pgant1 and galnt1

DIOPT Version :9

Sequence 1:	NP_611043.1	Gene:	Pgant1 / 36717	FlyBaseID:	FBgn0034025	Length:	601	Species:	Drosophila melanogaster
Sequence 2:	XP_009290644.1	Gene:	galnt1 / 559073	ZFINID:	ZDB-GENE-030131-2360	Length:	557	Species:	Danio rerio

Alignment Length:	529	Identity:	221/529 - (41%)
Similarity:	313/529 - (59%)	Gaps:	37/529 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly    83 LQKQKVGLGEQGVAVHLSGAAKERGDEIYKKIALNEELSEQLTYNRSVGDHRNPLCAKQRFDSDS 147
            :|:...|.||.|..|.::...:|:..|::|....|...||.:..|||:.|.|...| |.:...|.
Zfish    49 VQRPHDGPGEMGKPVVIAKDQQEKMKEMFKINQFNLMASEMIALNRSLPDVRLEGC-KTKVYPDD 112

  Fly   148 LPTASVVIIFFNEPYSVLLRTVHSTLSTCNEKALKEIILVDDGSDNVELGAKLDYYVR-TRIPSG 211
            ||..||||:|.||.::.|||||||.:.......|:||:||||.|:...|..:|::||| ..:|
Zfish   113 LPRTSVVIVFHNEAWTTLLRTVHSVIDRSPRHLLEEIVLVDDASERDFLKRQLEHYVRKLEVP-- 175

  Fly   212 KVTILRLKNRLGLIRARLAGARIATGDVLIFLDAHCEGNIGWCEPLLQRIKESRTSVLVPIIDVI 276
             |.::|::.|.|||||||.||.|:||.|:.|||||||...||.||||.|||..:.:|:.||||||
Zfish   176 -VRVVRMEQRSGLIRARLKGASISTGQVITFLDAHCECTTGWLEPLLSRIKLDKKTVVCPIIDVI 239

  Fly   277 DANDFQYSTNGYKSFQVGGFQWNGHFDWINLPEREKQRQRRECKQEREICPAYSPTMAGGLFAID 341
            ..:.|:|......::  |||.|..:|.|..:|:||..|:    |.:|.: |..:||||||||:||
Zfish   240 SDDTFEYMAGSDMTY--GGFNWKLNFRWYPVPQREMDRR----KGDRTL-PVRTPTMAGGLFSID 297

  Fly   342 RRYFWEVGSYDEQMDGWGGENLEMSFRIWQCGGTIETIPCSRVGHIFRDFHPYKFPNDRDTHGI- 405
            |.||.|:|:||..||.|||||||:||||||||||:|.:.||.|||:||...||.||.  .|..|
Zfish   298 RDYFQEIGTYDAGMDIWGGENLEISFRIWQCGGTLEIVTCSHVGHVFRKATPYTFPG--GTGQII 360

  Fly   406 --NTARMALVWMDEYINIFFLNRPDLKFHADIGDVTHRVMLRKKLRCKSFEWYLKNIYPEKFVPT 468
              |..|:|.|||||:.|.|::..|.:. ..|.||::.|..||::|:||.|.|||:|:||:..:|
Zfish   361 NKNNRRLAEVWMDEFKNFFYIISPGVT-KVDYGDISTRTSLRQRLQCKPFSWYLENVYPDSQIP- 423

  Fly   469 KDVQGWGKVHAVNSNICLDDLL-QNNEKPYNAGLYPCGKVLQKSQLFSFTNTNVLRNELSCATVQ 532
            :.....|::..|.:|.|||::. :.|||   .|::.| ..:..:|:||:|....:|.:..|..|.
Zfish   424 RHYYSLGEIRNVETNQCLDNMARKENEK---VGIFNC-HGMGGNQVFSYTANKEIRTDDLCLDVS 484

  Fly   533 HSESPPYRVVMVPCMENDEFNEQWRYE--HQHIIHSNTGMCLDHQGLKSLDDAQ---VAPCDPHS 592
            ....|   |:|:.| .:.:.|:.|.|:  ...::|.|:..|||.   .|.||:|   |..|. .:
Zfish   485 KLNGP---VMMLKC-HHLKGNQLWEYDPVKLSLVHVNSNQCLDK---ASEDDSQVPSVRDCS-GA 541

  Fly   593 ESQRWTIEH 601
            .||:|.:.:
Zfish   542 RSQQWLLRN 550

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Pgant1	NP_611043.1	WcaA	147..426	CDD:223539	144/282 (51%)
		pp-GalNAc-T	152..461	CDD:133004	157/312 (50%)
		Ricin_B_lectin	474..597	CDD:279046	38/128 (30%)
		RICIN	481..599	CDD:238092	37/123 (30%)
galnt1	XP_009290644.1	pp-GalNAc-T	117..417	CDD:133004	157/312 (50%)
		RICIN	430..548	CDD:238092	39/129 (30%)
		Ricin_B_lectin	430..546	CDD:279046	38/127 (30%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3736
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D606683at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11675
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	4	3.920