DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Pgant1 and galnt7

DIOPT Version :9

Sequence 1:	NP_611043.1	Gene:	Pgant1 / 36717	FlyBaseID:	FBgn0034025	Length:	601	Species:	Drosophila melanogaster
Sequence 2:	NP_001018477.1	Gene:	galnt7 / 553668	ZFINID:	ZDB-GENE-050522-284	Length:	652	Species:	Danio rerio

Alignment Length:	679	Identity:	206/679 - (30%)
Similarity:	318/679 - (46%)	Gaps:	123/679 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    10 GKLIIFILVALCF----ILYSKVQQNGSPEEPPVAPLVRAAALRGHGRERFEAYSDSENEIA--- 67
            |.::..:||...|    :|:|.:......:.|....:.|.|       ::....:...|.:|
Zfish     6 GFILRSLLVISTFLGLVLLWSSLTPKAGDDNPFAGVMAREA-------DKLPQPNLPNNNVADQF 63

  Fly    68 RPATQSPYEQIIQLDL------------------------QKQKV-------------------- 88
            :|....|:.:.:::||                        |||.:
Zfish    64 KPVVPWPHVEGVEVDLESIRQKNVDNPNPAFKAQNQQNVIQKQYITFKPHTNMYSDPVLNKGTLG 128

  Fly    89 --------------GLGEQGVAVHLSGAAKERGDEIYKKIALNEELSEQLTYNRSVGDHRNPLCA 139
                          |.||......|....|:......|:...|...|:.::.:|:|||.|:..|.
Zfish   129 NFEPKEPEPHGVQGGPGEGSKPFVLGPEYKDAVQASIKEFGFNMVASDMISLDRTVGDLRHEECK 193

  Fly   140 KQRFDSDSLPTASVVIIFFNEPYSVLLRTVHSTLSTCNEKALKEIILVDDGSDNVELGAKLDYYV 204
            ...:| ::|.|:||:|:|.||.:|.|:|||||.:.....|.|.||:::||.|:...|..:|:.|:
Zfish   194 YWNYD-ENLLTSSVIIVFHNEGWSTLMRTVHSVIKRTPRKYLAEIVMIDDFSNKAHLKERLEEYI 257

  Fly   205 RTRIPSGKVTILRLKNRLGLIRARLAGARIAT-GDVLIFLDAHCEGNIGWCEPLLQRIKESRTSV 268
            :..  :|.|.:.|.:.|.|||:||..|||.|| |.|||:||||||..:.|..||:..|.:.||..
Zfish   258 KQW--NGLVKVFRNEKREGLIQARSIGARKATLGKVLIYLDAHCEVGVNWYAPLVAPISKDRTVC 320

  Fly   269 LVPIIDVIDANDFQYSTNGYKSFQVGGFQ---WNGHFDWINLPEREKQRQRRECKQEREICPAYS 330
            .||:||.||.||:....      |.||.:   ..|.:||..|.:|.....|.:.|::.:..|..|
Zfish   321 TVPLIDYIDGNDYTIEP------QQGGDEDGLARGAWDWSLLWKRVPLSSREKAKRKHKTEPYRS 379

  Fly   331 PTMAGGLFAIDRRYFWEVGSYDEQMDGWGGENLEMSFRIWQCGGTIETIPCSRVGHIFR------ 389
            |.||||||||:|.:|:|:|.||..:..|||||.|:|::||||||.:..:||||||||:|
Zfish   380 PAMAGGLFAIEREFFFELGLYDPGLQIWGGENFEISYKIWQCGGQLLFVPCSRVGHIYRLQGWQG 444

  Fly   390 ---DFHPYKFPNDRDTHGINTARMALVWMDEYINIFFLNRPDLKFHADIGDVTHRVMLRKKLRCK 451
               ..|....|..:     |..|:..||.|:|.:.|:.:||:....| .||::.....|::.|||
Zfish   445 NPPPAHVGSSPTLK-----NYVRVVEVWWDDYKDYFYASRPETLTLA-YGDISTLKKFREEHRCK 503

  Fly   452 SFEWYLKNI-------YPEKFVPTKDVQGWGKVHAVNSNICLDDLLQNNEKPYNAGLYPCGKVLQ 509
            ||:|:::.|       ||   :|.|:|: ||::....::.|:|.:...|..  |..:.||.: :.
Zfish   504 SFKWFMEEIAYDIPLHYP---LPPKNVE-WGEIRGYETSYCIDSMGHTNGG--NVEIGPCHR-MG 561

  Fly   510 KSQLFSFTNTNVLRNELSCATVQHSESPPYRVVMVPCMENDEFNEQWRY--EHQHIIHSNTGMCL 572
            .:|||.....|.|.....|.|.....|   .|::..|..|:  :.:|:|  :.....|..||.||
Zfish   562 GNQLFRINEANQLMQYDQCLTKGGDGS---AVIITHCNLNE--HTEWKYFKDLHRFTHVPTGKCL 621

  Fly   573 DHQGLKSLDDAQVAPCDPHSESQRWTIEH 601
            |...:  |....:|.||....||:|.:.:
Zfish   622 DRSDV--LHKVYIADCDNSKSSQKWEMNN 648

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Pgant1	NP_611043.1	WcaA	147..426	CDD:223539	121/291 (42%)
		pp-GalNAc-T	152..461	CDD:133004	132/328 (40%)
		Ricin_B_lectin	474..597	CDD:279046	33/124 (27%)
		RICIN	481..599	CDD:238092	32/119 (27%)
galnt7	NP_001018477.1	pp-GalNAc-T	205..513	CDD:133004	131/321 (41%)
		BcsA	205..>433	CDD:224136	104/235 (44%)
		Ricin_B_lectin	529..644	CDD:279046	33/124 (27%)
		RICIN	530..646	CDD:238092	33/125 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D606683at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.920