Protein Alignment Pgant1 and Galnt4

DIOPT Version :10

• Sequence 1: NP_611043.1
• Gene: Pgant1 / 36717
• FlyBaseID: FBgn0034025
• Length: 601
• Species: Drosophila melanogaster
• Sequence 2: NP_001020224.2
• Gene: Galnt4 / 500826
• RGDID: 1564589
• Length: 578
• Species: Rattus norvegicus
• Alignment Length: 608
• Identity: 230/608 - (37%)
• Similarity: 327/608 - (53%)
• Gaps: 63/608 - (10%)

  Fly    13 IIFILVALCFILYSKVQQNGSPEEPPVAPLVRAAA---LRGHGRERFEAYSDSENEIARPATQSP 74
            ::..|:.|.:||.          |..|:.|..::.   .|..|..|...:...|.::::|..:.|
  Rat    13 LLLALLTLAYILV----------EFSVSTLYASSGADRARELGPRRLSDHETREEDLSQPLYKKP 67

  Fly    75 YEQIIQLDLQKQKVGLGEQGVAVHL---SGAAKERGDEIYKKIALNEELSEQLTYNRSVGDHRNP 136
                     ......|||.|.|..|   .|..|:: :|:.::.|:|..||::::.:|.:.|.|..
  Rat    68 ---------PADSHALGEWGRASKLQLDEGELKQQ-EELIERYAINIYLSDRISLHRHIEDKRMY 122

  Fly   137 LCAKQRFDSDSLPTASVVIIFFNEPYSVLLRTVHSTLSTCNEKALKEIILVDDGSDNVELGAKLD 201
            .|..::|...||||.||:|.|:||.:|.||||:||.|.|.....|||||||||.||.:.|.|:|:
  Rat   123 ECKAKKFHYRSLPTTSVIIAFYNEAWSTLLRTIHSVLETSPAVLLKEIILVDDLSDRIYLKAQLE 187

  Fly   202 YYVRTRIPSGKVTILRLKNRLGLIRARLAGARIATGDVLIFLDAHCEGNIGWCEPLLQRIKESRT 266
            .|:..   ..:|.::|...|.||:||||.||..||||||.|||.|||.|.||.||||:||....|
  Rat   188 AYISN---LDRVRLIRTNKREGLVRARLIGATFATGDVLTFLDCHCECNTGWLEPLLERISRDET 249

  Fly   267 SVLVPIIDVIDANDFQ-YSTNGYKSFQVGGFQWNGHFDWINLPEREKQRQRRECKQEREICPAYS 330
            :::.|:||.||.|.|: |...|..  .:|||.|...|.|.::|:.|:.|      :...|.|..|
  Rat   250 AIVCPVIDTIDWNTFEFYMQTGEP--MIGGFDWRLTFQWHSVPKHERDR------RTSRIDPIRS 306

  Fly   331 PTMAGGLFAIDRRYFWEVGSYDEQMDGWGGENLEMSFRIWQCGGTIETIPCSRVGHIFRDFHPYK 395
            |||||||||:.::||..:|:||..|:.|||||||:|||:|||||.:|..|||.|||:|....||.
  Rat   307 PTMAGGLFAVSKKYFQYLGTYDTGMEVWGGENLELSFRVWQCGGKLEIHPCSHVGHVFPKRAPYA 371

  Fly   396 FPNDRDTHGINTARMALVWMDEYINIFFLNRPDLKFHADIGDVTHRVMLRKKLRCKSFEWYLKNI 460
            .||...    ||||.|.||||:|...|:...|..: ....||::.|.:||::|:||||:|||||:
  Rat   372 RPNFLQ----NTARAAEVWMDDYKEHFYNRNPPAR-KETYGDISERKLLRERLQCKSFDWYLKNV 431

  Fly   461 YPEKFVPTKDVQGW-GKVHAVN-SNICLD-DLLQNNEKPYNAGLYPC-GKVLQKSQLFSFTNTNV 521
            :....|| :|..|| |.:.::. |:.||| :...||....|..|:.| |:  ..:|.|.:|:...
  Rat   432 FSNLHVP-EDRPGWHGAIRSMGISSECLDYNAPDNNPTGANLSLFGCHGQ--GGNQFFEYTSNKE 493

  Fly   522 LR----NELSCATVQHSESPPYRVVMVPCMEND---EFNEQWRY-EHQHIIHSNTGMCLD-HQGL 577
            :|    .|| ||.|...:.   .|.|..|.::.   ..|..|.: |...|.|.:|.:||. ::..
  Rat   494 IRFNSVTEL-CAEVPQQKD---YVGMQNCPKDGLPIPVNIIWHFKEDGTIFHPHTRLCLSAYRTA 554

  Fly   578 KSLDDAQVAPCDPHSESQRWTIE 600
            ......|:..||...::|.|..|
  Rat   555 DGRPSVQMKTCDALDKNQIWRFE 577

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pgant1	NP_611043.1	pp-GalNAc-T	152..461	CDD:133004	153/309 (50%)
		beta-trefoil_Ricin_Pgant1-like	468..601	CDD:467337	40/146 (27%)
Galnt4	NP_001020224.2	pp-GalNAc-T	138..432	CDD:133004	153/309 (50%)
		beta-trefoil_Ricin-like	442..577	CDD:483949	38/140 (27%)