DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Pgant1 and Galntl5

DIOPT Version :9

Sequence 1:	NP_611043.1	Gene:	Pgant1 / 36717	FlyBaseID:	FBgn0034025	Length:	601	Species:	Drosophila melanogaster
Sequence 2:	NP_001020319.1	Gene:	Galntl5 / 499968	RGDID:	1565271	Length:	443	Species:	Rattus norvegicus

Alignment Length:	351	Identity:	158/351 - (45%)
Similarity:	213/351 - (60%)	Gaps:	14/351 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly   113 KIALNEELSEQLTYNRSVGDHRNPLCAKQRFDSDSLPTASVVIIFFNEPYSVLLRTVHSTLSTCN 177
            :..||...|.:|...|.|.|.||.:|.::.:.. :||||||:|.|:||.::.|||||.|.::...
  Rat    85 RYGLNVITSRRLGIERQVPDSRNKICQQKHYPF-NLPTASVIICFYNEEFNTLLRTVSSVMNLSP 148

  Fly   178 EKALKEIILVDDGSDNVELGAKLDYYVRTRIPSGKVTILRLKNRLGLIRARLAGARIATGDVLIF 242
            :..|:|||||||.|:..:|.|||||::  .|..||:.::|.|.|.||||:|:.||..|:||:|:|
  Rat   149 KHLLEEIILVDDMSEFDDLKAKLDYHL--EIFRGKIKLVRNKKREGLIRSRMIGASRASGDILVF 211

  Fly   243 LDAHCEGNIGWCEPLLQRIKESRTSVLVPIIDVIDANDFQYSTNGYKSFQVGGFQWNGHFDWINL 307
            ||:|||.|..|.||||..|.:....|:.|:|||||.....|..:   ....|.|.||.:|.|.::
  Rat   212 LDSHCEVNRVWLEPLLHAIAKDHKMVVCPVIDVIDELTLDYVGS---PIVRGAFDWNLNFRWDDV 273

  Fly   308 PEREKQRQRRECKQEREICPAYSPTMAGGLFAIDRRYFWEVGSYDEQMDGWGGENLEMSFRIWQC 372
            ...|..      ..|....|..||.|:||:|||:|.||.|:|.||:.||.|||||:|:|.|||.|
  Rat   274 FSYELD------GPEGPSTPIRSPAMSGGIFAINRHYFNELGQYDKDMDLWGGENVELSLRIWMC 332

  Fly   373 GGTIETIPCSRVGHIFRDFHPYKFPNDRDTHGINTARMALVWMDEYINIFFLNRPDLKFHADIGD 437
            ||.:..:|||||||..:.....:..| :.....|..|:..||:|||...|||.||.|. |...|:
  Rat   333 GGQLFILPCSRVGHNNKALSKNRLVN-QSALSKNLLRVVHVWLDEYKENFFLQRPSLT-HVSCGN 395

  Fly   438 VTHRVMLRKKLRCKSFEWYLKNIYPE 463
            ::.||.|||:|.||||:|||.||:||
  Rat   396 ISDRVELRKRLGCKSFQWYLDNIFPE 421

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Pgant1	NP_611043.1	WcaA	147..426	CDD:223539	126/278 (45%)
		pp-GalNAc-T	152..461	CDD:133004	141/308 (46%)
		Ricin_B_lectin	474..597	CDD:279046
		RICIN	481..599	CDD:238092
Galntl5	NP_001020319.1	pp-GalNAc-T	123..419	CDD:133004	141/308 (46%)
Galntl5	NP_001020319.1	Glyco_tranf_2_3	123..355	CDD:290369	111/242 (46%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3736
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D606683at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.820