DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Pgant1 and galnt7

DIOPT Version :9

Sequence 1:	NP_611043.1	Gene:	Pgant1 / 36717	FlyBaseID:	FBgn0034025	Length:	601	Species:	Drosophila melanogaster
Sequence 2:	XP_012814191.2	Gene:	galnt7 / 407859	XenbaseID:	XB-GENE-950785	Length:	719	Species:	Xenopus tropicalis

Alignment Length:	698	Identity:	213/698 - (30%)
Similarity:	318/698 - (45%)	Gaps:	160/698 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly    10 GKLIIFILVALCFILY--------------SKVQQNGSPEEP---------------PVAPLVRA 45
            |.|:..:||...|:::              |::|:..:|..|               ||.|..|.
Frog    72 GFLLRSLLVLATFLMFLIIWTSFSSSGSTESRLQREENPNLPQAVKPDANAPKDDFHPVVPWPRV 136

  Fly    46 A-------ALRGHGRERFE---------------------------AYSDSENEIARPATQSPYE 76
            .       ::|...:||.|                           .|||   .:.||......|
Frog   137 EGVEVNLDSIRKKNKERLEQDHLEAKVNNQEHVMEKQYLTFKPQTHIYSD---PVLRPGILGNLE 198

  Fly    77 QIIQLDLQKQKV--GLGEQGVAVHLSGAAKERGDEIYKKIALNEELSEQLTYNRSVGDHRNPLCA 139
               ..:.:.|.|  |.||.|....|....|:......|:...|...|:.::.:|::.|.|:..|.
Frog   199 ---PKEPEPQGVVGGPGEGGKPFELGPDYKDAVKASIKEFGFNMVASDMISMDRTINDLRHEECK 260

  Fly   140 KQRFDSDSLPTASVVIIFFNEPYSVLLRTVHSTLSTCNEKALKEIILVDDGSDNVELGAKLDYYV 204
            ...:| ::|.|:||||:|.||.:|.|:||:||.:.....:.|.||:::||.|:...|..:||.|:
Frog   261 YWNYD-ENLLTSSVVIVFHNEGWSTLVRTIHSVIKRTPRQYLAEIVMIDDFSNKEHLKGRLDEYL 324

  Fly   205 RTRIPSGKVTILRLKNRLGLIRARLAGARIA-TGDVLIFLDAHCEGNIGWCEPLLQRIKESRTSV 268
            :..  :|.|.:.|.:.|.|||:||..||..| .|.|||:||||||..|.|..||:..|.:.||..
Frog   325 KQW--NGLVKVFRNERREGLIQARSIGAEKAKLGQVLIYLDAHCEVGINWYAPLIAPIAKDRTIC 387

  Fly   269 LVPIIDVIDANDFQYSTNGYKSFQVGGFQ-------WNGHFDWINLPEREKQRQRRECKQEREIC 326
            .||:|||||.|.::...      |.||.:       |:....|..:|...:::..|:.|.|
Frog   388 TVPLIDVIDGNTYELIP------QAGGDEDGFARGAWDWSMLWKRVPLTSREKAHRKAKTE---- 442

  Fly   327 PAYSPTMAGGLFAIDRRYFWEVGSYDEQMDGWGGENLEMSFRIWQCGGTIETIPCSRVGHIFRDF 391
            |..||.||||||||:|.||:|:|.||..:..|||||.|:|::||||||.:...||||||||:|
Frog   443 PYRSPAMAGGLFAIERDYFFELGLYDPGLQIWGGENFEISYKIWQCGGKLLFTPCSRVGHIYR-- 505

  Fly   392 HPYKFPNDRDTHG----------------INTARMALVWMDEYINIFFLNRPDLKF--HADIGDV 438
                      .||                .|..|:..||.|||.:.|:.:||:.|.  :.|||.:
Frog   506 ----------LHGWQGNPTPVYVGASPTLKNYIRVVEVWWDEYKDYFYASRPETKALPYGDIGPL 560

  Fly   439 THRVMLRKKLR----CKSFEWYLKNI-------YPEKFVPTKDVQGWGKVHAVNSNICLDDLLQN 492
                   ||.|    ||||:|:::.|       :|   :|.|:|: ||::....:|.|:|.:...
Frog   561 -------KKFREDHNCKSFKWFMEEIAYDITKYFP---LPPKNVE-WGEIRGFETNYCIDSMGHT 614

  Fly   493 NEKPYNAGLYPCGKV--LQKSQLFSFTNTNVLRNELSCATVQHSESPPYRVVMVPCMENDEFNEQ 555
                 |.|:...|..  :..:|||.....|.|.....|.    .:.|....||:......||.|
Frog   615 -----NGGIVELGGCHRMGGNQLFRINEANQLMQYDQCL----YKGPDGTQVMLTHCNLKEFLE- 669

  Fly   556 WRY-EHQH-IIHSNTGMCLDHQGLKSLDDAQVAPCDPHSESQRWTIEH 601
            |:| ::.| .:|.:||.|||..  :.|....::.||.:..:|:|.:.:
Frog   670 WQYFKNMHRFLHISTGKCLDRS--EVLHQVFLSDCDANKPTQKWEMNN 715

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Pgant1	NP_611043.1	WcaA	147..426	CDD:223539	121/302 (40%)
		pp-GalNAc-T	152..461	CDD:133004	134/345 (39%)
		Ricin_B_lectin	474..597	CDD:279046	33/126 (26%)
		RICIN	481..599	CDD:238092	32/121 (26%)
galnt7	XP_012814191.2	pp-GalNAc-T	272..580	CDD:133004	133/338 (39%)
galnt7	XP_012814191.2	Ricin_B_lectin	596..711	CDD:395527	33/126 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D606683at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.920