DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Pgant1 and Galnt16

DIOPT Version :9

Sequence 1:	NP_611043.1	Gene:	Pgant1 / 36717	FlyBaseID:	FBgn0034025	Length:	601	Species:	Drosophila melanogaster
Sequence 2:	NP_001094333.1	Gene:	Galnt16 / 362760	RGDID:	1310202	Length:	558	Species:	Rattus norvegicus

Alignment Length:	567	Identity:	215/567 - (37%)
Similarity:	302/567 - (53%)	Gaps:	56/567 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly    45 AAALRGHGRERFEAYSDSENE---IARPATQSPYEQIIQLDLQKQKVGLGEQGVAVHLSGAAKER 106
            ||:..|.|.:|.....:...|   |....|.:|.:            |..|:   .:||....:.
  Rat    32 AASSGGRGAQRAGGRPEQLREDRTIPLIVTGTPSK------------GFDEK---AYLSAKQLKP 81

  Fly   107 GDEIYKKIALNEELSEQLTYNRSVGDHRNPLCAKQRFDSDSLPTASVVIIFFNEPYSVLLRTVHS 171
            |::.|::.|.|:..|::|:.:|.:.|.|:..|....:.|| ||..||:|.|.||..|.|||||.|
  Rat    82 GEDPYRQHAFNQLESDKLSPDRPIRDTRHYSCPSLSYSSD-LPATSVIITFHNEARSTLLRTVKS 145

  Fly   172 TLSTCNEKALKEIILVDDGSDNVELGAKLDYYVRTRIPSGKVTILRLKNRLGLIRARLAGARIAT 236
            .|:......::|||||||.|.:.|     |..:.||||  ||..||...|.||||:|:.||.:|.
  Rat   146 VLNRTPAGLIQEIILVDDFSSDPE-----DCLLLTRIP--KVKCLRNDKREGLIRSRVRGADVAG 203

  Fly   237 GDVLIFLDAHCEGNIGWCEPLLQRIKESRTSVLVPIIDVIDANDFQYSTNGYKSFQV-GGFQWNG 300
            ..||.|||:|||.|:.|.:|:|||:.|..|.|:.||||||..::|.|..   .|..: |||.|:.
  Rat   204 ASVLTFLDSHCEVNVEWLQPMLQRVMEDHTRVVSPIIDVISLDNFAYLA---ASADLRGGFDWSL 265

  Fly   301 HFDWINLPEREKQRQRRECKQEREICPAYSPTMAGGLFAIDRRYFWEVGSYDEQMDGWGGENLEM 365
            ||.|..:|..:|..:....|      |..:|.:|||:|.||:.:|..:|.||.|||.|||||.|:
  Rat   266 HFKWEQIPLEQKMTRTDPTK------PIRTPVIAGGIFVIDKSWFNHLGKYDAQMDIWGGENFEL 324

  Fly   366 SFRIWQCGGTIETIPCSRVGHIFRDFHPYKFPNDRD-THGINTARMALVWMDEYINIFFLNRPDL 429
            |||:|.|||::|.:|||||||:||..|||.||.... |:..||.|.|.||||||...::..||..
  Rat   325 SFRVWMCGGSLEIVPCSRVGHVFRKRHPYNFPEGNALTYIRNTKRTAEVWMDEYKQYYYEARPSA 389

  Fly   430 KFHADIGDVTHRVMLRKKLRCKSFEWYLKNIYPEKFVPTKDVQGWGKVHAVNSNICLDDLLQNNE 494
            ...| .|.|..|:..|||:.||||.|||:|:|||..||.|:|........||   ||:...||..
  Rat   390 IGKA-FGSVATRIEQRKKMDCKSFRWYLENVYPELTVPVKEVLPGVIKQGVN---CLESQGQNTA 450

  Fly   495 KPYNAGLYPC---GKVLQKSQLFSFTNTNVLRNELSC--ATVQHSESPPYRVVMVPCMENDEFNE 554
            .....|:..|   .|....:|.:.|:: ::::.:..|  ||.....||...||:..| ...|..:
  Rat   451 GDLLLGMGICRGSAKSPPPAQAWLFSD-HLIQQQGKCLAATSTLMSSPGSPVVLQSC-NPKEGKQ 513

  Fly   555 QWRYEHQHIIHSNTGMCLDHQGLKSLDDAQVA--PCDPHSESQRWTI 599
            :||.:...|.||.:|:||:.:      .||:.  .|...:::|:|.:
  Rat   514 KWRRKGSFIQHSVSGLCLETK------PAQLVTNKCQADAQAQQWQL 554

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Pgant1	NP_611043.1	WcaA	147..426	CDD:223539	133/280 (48%)
		pp-GalNAc-T	152..461	CDD:133004	148/310 (48%)
		Ricin_B_lectin	474..597	CDD:279046	32/129 (25%)
		RICIN	481..599	CDD:238092	32/124 (26%)
Galnt16	NP_001094333.1	pp-GalNAc-T	126..420	CDD:133004	148/310 (48%)
		WcaA	126..>222	CDD:223539	51/102 (50%)
		Ricin_B_lectin	441..543	CDD:279046	28/109 (26%)
		RICIN	441..543	CDD:238092	28/109 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3736
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D606683at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.820