Protein Alignment Pgant1 and Galntl6

DIOPT Version :10

• Sequence 1: NP_611043.1
• Gene: Pgant1 / 36717
• FlyBaseID: FBgn0034025
• Length: 601
• Species: Drosophila melanogaster
• Sequence 2: NP_001129228.1
• Gene: Galntl6 / 361142
• RGDID: 1564773
• Length: 601
• Species: Rattus norvegicus
• Alignment Length: 621
• Identity: 204/621 - (32%)
• Similarity: 316/621 - (50%)
• Gaps: 74/621 - (11%)

  Fly    11 KLIIFILVALCFI-------LY--SKVQQNGSPEEPPVAPLVRAAALRGHGRERFEAYSDSENEI 66
            ::.:...|||.|:       ||  ..:.::..|.|....||       |.|..:|.:::|.
  Rat    10 QMTLLFTVALIFLPNIGLWSLYKDKHLMKSAEPAEHQTFPL-------GLGDGQFYSWTDG---- 63

  Fly    67 ARPATQSPYEQIIQLDLQKQKVGLGEQGVAVHLSGAAKERGDEIYKKIALNEELSEQLTYNRSVG 131
               ..:..:...:.:.....:.|.||.|....|:  .::..|..|::...|..:|..:...||:.
  Rat    64 ---LRRKDWHDYVSIQKDALRSGKGEHGKPYPLT--EEDHDDSAYRENGFNIFVSNNIALERSLP 123

  Fly   132 DHRNPLCAKQRFDSDSLPTASVVIIFFNEPYSVLLRTVHSTLSTCNEKALKEIILVDDGSDNVEL 196
            |.|:..| |.:...:.||..|::|.|.||.::.||||:||.::...|..:.|||||||.||...|
  Rat   124 DIRHANC-KHKMYLERLPNTSIIIPFHNEGWTSLLRTIHSIINRTPESLIAEIILVDDFSDREHL 187

  Fly   197 GAKLDYYVRTRIPSGKVTILRLKNRLGLIRARLAGARIATGDVLIFLDAHCEGNIGWCEPLLQRI 261
            ..||:.|: .|.|.  |.|:|.|.|.||||.||.||.:|.|:||.|||:|||.|:.|..|||.:|
  Rat   188 KDKLEDYM-ARFPI--VRIVRTKKREGLIRTRLLGASVARGEVLTFLDSHCEVNVNWLPPLLNQI 249

  Fly   262 KESRTSVLVPIIDVIDANDFQYSTNGYKSFQVGGFQWNGHFDWINLPEREKQRQRRECKQEREIC 326
            ..:..:::.|:|||||.:.|.|......:.: |.|.|..::..|.:|   .:.||.:..:
  Rat   250 ALNHKTIVCPMIDVIDHSHFGYEAQAGDAMR-GAFDWEMYYKRIPIP---PELQRADPSE----- 305

  Fly   327 PAYSPTMAGGLFAIDRRYFWEVGSYDEQMDGWGGENLEMSFRIWQCGGTIETIPCSRVGHIFRDF 391
            |..||.|||||||:||::|||:|.||..::.||||..|:||::|.|||.:..:||||||||:|.:
  Rat   306 PFESPVMAGGLFAVDRKWFWELGGYDPGLEIWGGEQYEISFKVWMCGGEMFDVPCSRVGHIYRKY 370

  Fly   392 HPYKFPNDRDTHGINTARMALVWMDEYINIFFLNRPDLKFHADIGDVTHRVMLRKKLRCKSFEWY 456
            .|||.|:.... ..|..|:|..||||:....:..||:.: |...||::.:..|||:|:||.|:|:
  Rat   371 VPYKVPSGTSL-ARNLKRVAETWMDEFAEYIYQRRPEYR-HLSTGDISAQKELRKRLKCKDFKWF 433

  Fly   457 LKNI---YPEKFVPTKDV-QGWGKVHAVNSNICLDDLLQNNEKPYNAGLYPCGK-----VLQKSQ 512
            :..:   .|:.:.|.:.: ..||::..|.:|:|:|.  ::........|..|.|     .....|
  Rat   434 MAAVAWDVPKYYPPVEPLPAAWGEIRNVAANLCVDS--KHGAMGTELRLDICVKDGSERTWSHEQ 496

  Fly   513 LFSFTNTNVLR-------NELSCATVQHSESPPYRVVMVPCMENDEFNEQWRY-EHQHIIHSNTG 569
            ||:|.....:|       .:.....:.|| ||   |.:..| ...:.|:.|.| |.:.:.|..:.
  Rat   497 LFTFGWREDIRPGEPLHTRKFCLDAISHS-SP---VTLYDC-HGMKGNQLWGYREDRTLFHPVSN 556

  Fly   570 MCLDHQGLKSLDDAQ----VAPCDPHSESQRWTIEH 601
            .|:|      .:.|:    :|.|||.||:|:|..||
  Rat   557 SCMD------CNPAEKKVFMARCDPLSETQQWMFEH 586

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pgant1	NP_611043.1	pp-GalNAc-T	152..461	CDD:133004	133/311 (43%)
		beta-trefoil_Ricin_Pgant1-like	468..601	CDD:467337	36/150 (24%)
Galntl6	NP_001129228.1	pp-GalNAc-T	143..438	CDD:133004	133/308 (43%)
		beta-trefoil_Ricin_GALNTL6	449..594	CDD:467355	38/151 (25%)