Protein Alignment Pgant1 and Pgant3

DIOPT Version :10

• Sequence 1: NP_611043.1
• Gene: Pgant1 / 36717
• FlyBaseID: FBgn0034025
• Length: 601
• Species: Drosophila melanogaster
• Sequence 2: NP_610256.1
• Gene: Pgant3 / 35627
• FlyBaseID: FBgn0027558
• Length: 667
• Species: Drosophila melanogaster
• Alignment Length: 680
• Identity: 228/680 - (33%)
• Similarity: 331/680 - (48%)
• Gaps: 117/680 - (17%)

  Fly     1 MLPRFRSFYGKLIIFILVALCFILYSKVQQNGSPEEPPVAPLVRAAALRGHGRERFEAYSDSENE 65
            :|..|..|:.    |.:.|:...||....|.|..|.....|..:..:|..|  :...|:...:.:
  Fly    13 LLYLFLLFFA----FFMFAISINLYVASIQGGDAEMRHPKPPPKRRSLWPH--KNIVAHYIGKGD 71

  Fly    66 IARPATQSPYEQIIQLDLQKQKVGLGEQGVAVHLSGAAKERGDEIYKKIALNEELSEQLTYNRSV 130
            |....|...|    .::|.:...|.|..|..|.:....:.|....::..:.|...|:::..||::
  Fly    72 IFGNMTADDY----NINLFQPINGEGADGRPVVVPPRDRFRMQRFFRLNSFNLLASDRIPLNRTL 132

  Fly   131 GDHRNPLCAKQRFDSDSLPTASVVIIFFNEPYSVLLRTVHSTLSTCNEKALKEIILVDDGSDNVE 195
            .|:|.|.|..:::.| .||:.||:|:|.||.:||||||:.|.::......|||||||||.||...
  Fly   133 KDYRTPECRDKKYAS-GLPSTSVIIVFHNEAWSVLLRTITSVINRSPRHLLKEIILVDDASDRSY 196

  Fly   196 LGAKLDYYVRT-RIPSGKVTILRLKNRLGLIRARLAGARIATGDVLIFLDAHCEGNIGWCEPLLQ 259
            |..:|:.||:. .:|:   .|.|:|.|.||:.|||.||..|.||||.|||||||.:.||.||||.
  Fly   197 LKRQLESYVKVLAVPT---RIFRMKKRSGLVPARLLGAENARGDVLTFLDAHCECSRGWLEPLLS 258

  Fly   260 RIKESRTSVLVPIIDVIDANDFQYSTNGYKSFQ--VGGFQWNGHFDWINLPEREKQRQRRECKQE 322
            ||||||..|:.|:||:|..::|.|:    |:|:  .|.|.|...|.|.: .:|::|......|..
  Fly   259 RIKESRKVVICPVIDIISDDNFSYT----KTFENHWGAFNWQLSFRWFS-SDRKRQTAGNSSKDS 318

  Fly   323 REICPAYSPTMAGGLFAIDRRYFWEVGSYDEQMDGWGGENLEMSFRIWQCGGTIETIPCSRVGHI 387
            .:  |..:|.||||||||||:||:|:||||..|..|||||:|||||||||||.:|..|||.|||:
  Fly   319 TD--PIATPGMAGGLFAIDRKYFYEMGSYDSNMRVWGGENVEMSFRIWQCGGRVEISPCSHVGHV 381

  Fly   388 FRDFHPYKFPNDRDTHGI------NTARMALVWMDEYINIFFLNRPDLKFHA-DIGDVTHRVMLR 445
            ||...||.||.     |:      |.||.|.||||::.....|....|...| |..:||.||.||
  Fly   382 FRSSTPYTFPG-----GMSEVLTDNLARAATVWMDDWQYFIMLYTSGLTLGAKDKVNVTERVALR 441

  Fly   446 KKLRCKSFEWYLKNIYPEKFVPTKDVQGWGKV---------------HAVN-------------- 481
            ::|:||.|.|||:||:||.|.|..| :.:||:               |..|
  Fly   442 ERLQCKPFSWYLENIWPEHFFPAPD-RFFGKIIWLDGETECAQAYSKHMKNLPGRALSREWKRAF 505

  Fly   482 -----------------SNICL----DDLLQNNEKPYNAGLYPCGKVLQKSQLFSFT-NTNVLRN 524
                             .:.||    :|:.:::......|  .|....|...:|..| ...::.|
  Fly   506 EEIDSKAEELMALIDLERDKCLRPLKEDVPRSSLSAVTVG--DCTSHAQSMDMFVITPKGQIMTN 568

  Fly   525 ELSCAT-----------VQHSESPPYRVVMVPCMENDEFNEQWRY--EHQHIIHSNTGMCLDHQG 576
            :..|.|           :::..:....|::..|..:.  ::.|.|  :.|.|.|.:|.:||.
  Fly   569 DNVCLTYRQQKLGVIKMLKNRNATTSNVMLAQCASDS--SQLWTYDMDTQQISHRDTKLCLT--- 628

  Fly   577 LKSLDDAQV---------APCDPHSESQRW 597
            ||:..::::         ..||....:|:|
  Fly   629 LKAATNSRLQKVEKVVLSMECDFKDITQKW 658

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pgant1	NP_611043.1	pp-GalNAc-T	152..461	CDD:133004	157/318 (49%)
		beta-trefoil_Ricin_Pgant1-like	468..601	CDD:467337	32/203 (16%)
Pgant3	NP_610256.1	pp-GalNAc-T	153..457	CDD:133004	157/318 (49%)
		beta-trefoil_Ricin_Pgant3-like	515..661	CDD:467338	27/151 (18%)