Protein Alignment Pgant1 and Galnt13

DIOPT Version :10

• Sequence 1: NP_611043.1
• Gene: Pgant1 / 36717
• FlyBaseID: FBgn0034025
• Length: 601
• Species: Drosophila melanogaster
• Sequence 2: XP_036018146.1
• Gene: Galnt13 / 271786
• MGIID: 2139447
• Length: 613
• Species: Mus musculus
• Alignment Length: 650
• Identity: 231/650 - (35%)
• Similarity: 330/650 - (50%)
• Gaps: 112/650 - (17%)

  Fly     6 RSFYGKLII-----FILVALCFILY-SKVQQNGSPEEPPVAPLVRAAALRGHGRERFEAYSDSEN 64
            |..|.|:::     ::||.:..:|| |:..:....:|..:.|.:||.
Mouse     3 RFVYCKVVLATSLMWVLVDVFLLLYFSECNKCDDKKERSLLPALRAV------------------ 49

  Fly    65 EIARPATQSPYEQIIQLDLQKQKVGLGEQGVAVHLSGAAKERGDEIYKKIALNEELSEQLTYNRS 129
                              :.:.:.|.||.|.||.:....:|:..|::|....|...|:.:..|||
Mouse    50 ------------------ISRNQEGPGEMGKAVLIPKDDQEKMKELFKINQFNLMASDLIALNRS 96

  Fly   130 VGDHR-----------------------------------------NPLCAKQRFDSDSLPTASV 153
            :.|.|                                         ..|..|.:...|.||..||
Mouse    97 LPDVRLEGQYCCGRCEELQTMQQERYARVYISTNFCSSILFWLKCNTELRCKTKVYPDELPNTSV 161

  Fly   154 VIIFFNEPYSVLLRTVHSTLSTCNEKALKEIILVDDGSDNVELGAKLDYYVRT-RIPSGKVTILR 217
            ||:|.||.:|.|||||:|.::......|.|:|||||.|:...|...|:.||:| .:|   |.|:|
Mouse   162 VIVFHNEAWSTLLRTVYSVINRSPHYLLSEVILVDDASERDFLKLTLENYVKTLEVP---VKIIR 223

  Fly   218 LKNRLGLIRARLAGARIATGDVLIFLDAHCEGNIGWCEPLLQRIKESRTSVLVPIIDVIDANDFQ 282
            ::.|.|||||||.||..:.|.|:.|||||||..:||.||||.||||.|.:|:.||||||..:.|:
Mouse   224 MEERSGLIRARLRGAAASKGQVITFLDAHCECTLGWLEPLLARIKEDRKTVVCPIIDVISDDTFE 288

  Fly   283 YSTNGYKSFQVGGFQWNGHFDWINLPEREKQRQRRECKQEREICPAYSPTMAGGLFAIDRRYFWE 347
            |......::  |||.|..:|.|..:|:||..|:    |.:|.: |..:||||||||:|||.||.|
Mouse   289 YMAGSDMTY--GGFNWKLNFRWYPVPQREMDRR----KGDRTL-PVRTPTMAGGLFSIDRNYFEE 346

  Fly   348 VGSYDEQMDGWGGENLEMSFRIWQCGGTIETIPCSRVGHIFRDFHPYKFPNDRDTHGI--NTARM 410
            :|:||..||.|||||||||||||||||::|.:.||.|||:||...||.||.... |.|  |..|:
Mouse   347 IGTYDAGMDIWGGENLEMSFRIWQCGGSLEIVTCSHVGHVFRKATPYTFPGGTG-HVINKNNRRL 410

  Fly   411 ALVWMDEYINIFFLNRPDLKFHADIGDVTHRVMLRKKLRCKSFEWYLKNIYPEKFVPTKDVQGWG 475
            |.|||||:.:.|::..|.: ...|.|||:.|..||:.|:||.|.|||:||||:..:|.: ....|
Mouse   411 AEVWMDEFKDFFYIISPGV-VKVDYGDVSVRKTLRENLKCKPFSWYLENIYPDSQIPRR-YYSLG 473

  Fly   476 KVHAVNSNICLDDL-LQNNEKPYNAGLYPCGKVLQKSQLFSFTNTNVLRNELSCATVQHSESPPY 539
            ::..|.:|.|||:: .:.|||   .|::.| ..:..:|:||:|....:|.:..|..|.....|
Mouse   474 EIRNVETNQCLDNMGRKENEK---VGIFNC-HGMGGNQVFSYTADKEIRTDDLCLDVSRLSGP-- 532

  Fly   540 RVVMVPCMENDEFNEQWRY--EHQHIIHSNTGMCLD-HQGLKSLDDAQVAPCDPHSESQRWTIEH 601
             |:|:.| .:...|:.|.|  |...::|..|..||. .:|.....|..:..|: .|..|:|.:.:
Mouse   533 -VIMLKC-HHMRGNQLWEYDAETHTLVHIITQSCLSMGKGEDGSQDLSMETCN-DSTFQKWLLRN 594

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pgant1	NP_611043.1	pp-GalNAc-T	152..461	CDD:133004	158/311 (51%)
		beta-trefoil_Ricin_Pgant1-like	468..601	CDD:467337	36/136 (26%)
Galnt13	XP_036018146.1	pp-GalNAc-T	160..460	CDD:133004	158/311 (51%)
		beta-trefoil_Ricin-like	467..594	CDD:483949	36/136 (26%)