Protein Alignment Pgant1 and gly-7

DIOPT Version :10

• Sequence 1: NP_611043.1
• Gene: Pgant1 / 36717
• FlyBaseID: FBgn0034025
• Length: 601
• Species: Drosophila melanogaster
• Sequence 2: NP_503512.1
• Gene: gly-7 / 178661
• WormBaseID: WBGene00001632
• Length: 601
• Species: Caenorhabditis elegans
• Alignment Length: 573
• Identity: 194/573 - (33%)
• Similarity: 284/573 - (49%)
• Gaps: 99/573 - (17%)

  Fly    59 YSDSENEIARPATQSPYEQIIQLDLQKQKVGLGEQGVAVHLS---GAAKERGDEIYKKIALNEEL 120
            |...|.||  |:.|.                 ||.|..|.::   |.|..|..|  |:...|..:
 Worm    85 YEPKEPEI--PSNQP-----------------GEHGKPVPVTDEEGMAAGRAAE--KEFGFNTYV 128

  Fly   121 SEQLTYNRSVGDHRNPLCAKQRFD-SDSLPTASVVIIFFNEPYSVLLRTVHSTLSTCNEKALKEI 184
            |:.::.||::.|.|...|  :.:| .:.|||.|||::|.||.::.|||||||.|.....:.::::
 Worm   129 SDMISMNRTIPDIRPEEC--KHWDYPEKLPTVSVVVVFHNEGWTPLLRTVHSVLLRSPPELIEQV 191

  Fly   185 ILVDDGSDNVELGAKLDYYVRTRIPSGKVTILRLKNRLGLIRARLAGARIATGDVLIFLDAHCEG 249
            ::|||.||...|..|||.|| ||. :|||.::|.:.|.|||.||..||:.:||:|::|||||||.
 Worm   192 VMVDDDSDKPHLKEKLDKYV-TRF-NGKVIVVRTEQREGLINARSIGAKHSTGEVVLFLDAHCEV 254

  Fly   250 NIGWCEPLLQRIKESRTSVLVPIIDVIDANDFQY-----STNGYKSFQVGGFQWNGHFDWINLPE 309
            |..|..|||..||.:|..:.||:||.||:|.::|     |.|.:.|   |.|:|...:....:.|
 Worm   255 NTNWLPPLLAPIKRNRKVMTVPVIDGIDSNSWEYRSVYGSPNAHHS---GIFEWGLLYKETQITE 316

  Fly   310 REKQRQRRECKQEREICPAYSPTMAGGLFAIDRRYFWEVGSYDEQMDGWGGENLEMSFRIWQCGG 374
            ||...::...:      |..|||.|||||||:|.:|.|:|.|||.:..||||..|:||:||||||
 Worm   317 RETAHRKHNSQ------PFRSPTHAGGLFAINRLWFKELGYYDEGLQIWGGEQYELSFKIWQCGG 375

  Fly   375 TIETIPCSRVGHIFRDFHPYKFP--NDRDTHGINTARMALVWMDEYINIFFLNRPDLKFHADIGD 437
            .|..:|||.|||::|...||.|.  :.:....||..|:...|||:| :.::|.|.....:.:.||
 Worm   376 GIVFVPCSHVGHVYRSHMPYSFGKFSGKPVISINMMRVVKTWMDDY-SKYYLTREPQATNVNPGD 439

  Fly   438 VTHRVMLRKKLRCKSFEWYLKNI-------YPEKFVPTKDVQGWGKVHAVNSNICLDDLLQNNEK 495
            ::.::.||.||:||||:||::|:       ||  .:|..||  ||:.....:..|||.:   ...
 Worm   440 ISAQLALRDKLQCKSFKWYMENVAYDVLKSYP--MLPPNDV--WGEARNPATGKCLDRM---GGI 497

  Fly   496 PYNAGLYPC--------------GKVLQKSQLFSFTNTNVLRNELSCATVQHSESPPYRVVMVPC 546
            |...|...|              |::.|.....:.....:..|.....||
 Worm   498 PGPMGATGCHGYGGNQLIRLNVQGQMAQGEWCLTANGIRIQANHCVKGTV--------------- 547

  Fly   547 MENDEFNEQWRYEH--QHIIHSNTGMCLDHQGLKSLDDAQVAPCDPHSESQRW 597
                  |..|.|:.  :.||||....|:...  :|..:..:..|...:|.|::
 Worm   548 ------NGFWSYDRKTKQIIHSQKRQCITVS--ESGSEVTLQTCTEDNERQKF 592

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pgant1	NP_611043.1	pp-GalNAc-T	152..461	CDD:133004	138/322 (43%)
		beta-trefoil_Ricin_Pgant1-like	468..601	CDD:467337	27/146 (18%)
gly-7	NP_503512.1	pp-GalNAc-T	159..463	CDD:133004	138/315 (44%)
		beta-trefoil_Ricin_GALNT7	475..596	CDD:467315	27/146 (18%)