DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Pgant1 and Galnt10

DIOPT Version :9

Sequence 1:	NP_611043.1	Gene:	Pgant1 / 36717	FlyBaseID:	FBgn0034025	Length:	601	Species:	Drosophila melanogaster
Sequence 2:	XP_038941033.1	Gene:	Galnt10 / 170501	RGDID:	69409	Length:	752	Species:	Rattus norvegicus

Alignment Length:	542	Identity:	206/542 - (38%)
Similarity:	300/542 - (55%)	Gaps:	61/542 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly    86 QKVGLGEQGVAVHLSGAAKERGDEIYKKIALNEELSEQLTYNRSVGDHRNPLCAKQRFDSDSLPT 150
            |:||.||||....::.|  ||.|:.|::...|..:|::::.|||:.|.|:|.|..:.: .::||.
  Rat   234 QRVGNGEQGKPYPMTDA--ERVDQAYRENGFNIYVSDKISLNRSLPDIRHPNCNSKLY-LETLPN 295

  Fly   151 ASVVIIFFNEPYSVLLRTVHSTLSTCNEKALKEIILVDDGSDNVELGAKLDYYVRTRIPSGKVTI 215
            .|::|.|.||.:|.|||||||.|:....:.:.||:||||.||...|...|:.|: ...||  |.|
  Rat   296 TSIIIPFHNEGWSSLLRTVHSVLNRSPPELVAEIVLVDDFSDREHLKKPLEDYM-ALFPS--VRI 357

  Fly   216 LRLKNRLGLIRARLAGARIATGDVLIFLDAHCEGNIGWCEPLLQRIKESRTSVLVPIIDVIDAND 280
            ||.|.|.||||.|:.||..|||||:.|||:|||.|:.|..|||.||..:|.:::.|:|||||.:|
  Rat   358 LRTKKREGLIRTRMLGASAATGDVITFLDSHCEANVNWLPPLLDRIARNRKTIVCPMIDVIDHDD 422

  Fly   281 FQYSTNGYKSFQVGGFQWNGHFDWINLPEREKQRQRRECKQEREICPAYSPTMAGGLFAIDRRYF 345
            |:|.|....:.: |.|.|..::..|.:|.        |.::.....|..||.|||||||:||::|
  Rat   423 FRYETQAGDAMR-GAFDWEMYYKRIPIPP--------ELQKADPSDPFESPVMAGGLFAVDRKWF 478

  Fly   346 WEVGSYDEQMDGWGGENLEMSFRIWQCGGTIETIPCSRVGHIFRDFHPYKFPNDRDTHGI----N 406
            ||:|.||..::.||||..|:||::|.|||.:|.|||||||||:|.:.|||.|     .|:    |
  Rat   479 WELGGYDPGLEIWGGEQYEISFKVWMCGGRMEDIPCSRVGHIYRKYVPYKVP-----AGVSLARN 538

  Fly   407 TARMALVWMDEYINIFFLNRPDLKFHADIGDVTHRVMLRKKLRCKSFEWYLKNI---YPEKFVPT 468
            ..|:|.||||||....:..||:.: |...|||..:..||..|.||||:|::..|   .|:.:.|.
  Rat   539 LKRVAEVWMDEYAEYIYQRRPEYR-HLSAGDVVAQKKLRGSLNCKSFKWFMTKIAWDLPKFYPPV 602

  Fly   469 K-DVQGWGKVHAVNSNICLDDLLQNNEKPYNAGLYPC----GKVLQKS-QLFSFTNTNVLRNELS 527
            : ....||::..|.:.:|.|........|..  |..|    |:....| |:|:||    .|.::.
  Rat   603 EPPAAAWGEIRNVGTGLCTDTKHGTLGSPLR--LETCIRGRGEAAWNSMQVFTFT----WREDIR 661

  Fly   528 CATVQHSE----------SPPYRVVMVPCMENDEFNEQWRY-EHQHIIHSNTGMCLDHQGLKSLD 581
            ....||::          ||   |.:..| .:.:.|:.|:| :.:.:.|..:|.|:|    .|..
  Rat   662 PGDPQHTKKFCFDAVSHTSP---VTLYDC-HSMKGNQLWKYRKDKTLYHPVSGSCMD----CSES 718

  Fly   582 DAQV--APCDPHSESQRWTIEH 601
            |.::  ..|:|.|.:|:|..||
  Rat   719 DHRIFMNTCNPSSLTQQWLFEH 740

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Pgant1	NP_611043.1	WcaA	147..426	CDD:223539	131/282 (46%)
		pp-GalNAc-T	152..461	CDD:133004	144/315 (46%)
		Ricin_B_lectin	474..597	CDD:279046	34/140 (24%)
		RICIN	481..599	CDD:238092	32/135 (24%)
Galnt10	XP_038941033.1	pp-GalNAc-T	297..592	CDD:133004	143/312 (46%)
Galnt10	XP_038941033.1	Ricin_B_lectin	608..736	CDD:395527	34/141 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3736
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810