Protein Alignment Pgant1 and Pgant3

DIOPT Version :10

• Sequence 1: NP_611043.1
• Gene: Pgant1 / 36717
• FlyBaseID: FBgn0034025
• Length: 601
• Species: Drosophila melanogaster
• Sequence 2: XP_317241.5
• Gene: Pgant3 / 1277750
• VectorBaseID: AGAMI1_009991
• Length: 664
• Species: Anopheles gambiae
• Alignment Length: 659
• Identity: 220/659 - (33%)
• Similarity: 328/659 - (49%)
• Gaps: 117/659 - (17%)

  Fly     4 RFRSFYGKLII-FILVALCFILYSK------------VQQNGSPEEPPVAPLVRAAALRGHGRER 55
            |.:.||..:|| |:.....|.|.||            |:.|..|:.|.:..:|......|.....
Mosquito     6 RVKIFYVYIIISFVFSVYLFYLISKYSFEKFINYHRHVRSNKFPDRPRIPQIVGHYVGVGTVGNL 70

  Fly    56 FEAYSDSENEIARPATQSPYEQIIQLDLQKQKVGLGEQGVAVHLSGAAKERGDEIYKKIALNEEL 120
            .:.:.::.|....|                   |:||.|..|.:......:..::::....|...
Mosquito    71 SKDFMNTNNFDPIP-------------------GVGEHGDPVVIQAKDLLKMQQLFQINRYNLLA 116

  Fly   121 SEQLTYNRSVGDHRNPLCAKQRFDSDSLPTASVVIIFFNEPYSVLLRTVHSTLSTCNEKALKEII 185
            |:::..|||:.|.|.|.|..:.:.: .|||.|::|:|.||.:|||||||.|.::...:..::||:
Mosquito   117 SDRIALNRSLPDVRKPKCVSKLYPA-KLPTTSIIIVFHNEAWSVLLRTVWSVINRSPKGLVREIL 180

  Fly   186 LVDDGSDNVELGAKLDYYVRTRIPSGKVTILRLKNRLGLIRARLAGARIATGDVLIFLDAHCEGN 250
            ||||.||...|..:||.||: ::|. .||||||..|.||:.|||.|||:||||.|.|||||||.:
Mosquito   181 LVDDASDRRFLKHELDNYVQ-KLPL-SVTILRLNKREGLVAARLLGARMATGDTLTFLDAHCECS 243

  Fly   251 IGWCEPLLQRIKESRTSVLVPIIDVIDANDFQYSTNGYKSFQV--GGFQWNGHFDWINLPEREKQ 313
            .||.||||.|::|:...|:.|:||:|..::|.|    .|||:.  |.|.|..||.|..|.:.|..
Mosquito   244 PGWLEPLLARVQENPKKVVCPVIDIISDDNFSY----IKSFEFHWGAFNWPLHFRWYTLSDEELA 304

  Fly   314 RQRRECKQEREICPAYSPTMAGGLFAIDRRYFWEVGSYDEQMDGWGGENLEMSFRIWQCGGTIET 378
            .:|::     ...|..:|.||||||.|||:||:::|:|||::..|||:|||||||:|||||.:|.
Mosquito   305 ERRKD-----TTTPFRTPAMAGGLFTIDRKYFFDIGAYDERLKIWGGDNLEMSFRVWQCGGEVEI 364

  Fly   379 IPCSRVGHIFRDFHPYKFPNDRDTHGI---NTARMALVWMDEYINIFF-LNRPDLKFHADIGDVT 439
            .|||.|||:||...||.||.  ...||   |.||:||||||::...|| .|:...:|.:  .:|:
Mosquito   365 APCSHVGHLFRKSSPYTFPG--GVSGILNENLARVALVWMDDWAKFFFKFNKGTEEFKS--LNVS 425

  Fly   440 HRVMLRKKLRCKSFEWYLKNIYPEKFVPTKDVQGWGKVHAVNSNICLD-----------DLLQNN 493
            :|:.|::.|.||||:|||:.::|:.|.|..: :.:|::..::.....|           :|:..|
Mosquito   426 NRLALKRSLNCKSFDWYLRQVWPQNFFPAPN-KFFGRIQPIDLTSTFDYQEYLTLMKKINLIIKN 489

  Fly   494 EKPYNAGLYPCGKVLQKSQLFSFTNTNVLRNELSCATVQHSESPPYRVVMVPCMENDEFN----- 553
            ..|          .|:...|..:...||.|...|....:||   ||      |:...:.|
Mosquito   490 LNP----------ELKWKFLIKYLTENVKRIGDSMKAAKHS---PY------CLHKPKTNTAINQ 535

  Fly   554 ------------------EQWRYEHQHIIHSNTGMCLDHQGLKSLDDAQV---------APCDPH 591
                              ||:..:....:.::.|:|||.....|:|..::         ..|...
Mosquito   536 PYGQAYLQKCSLLINVLDEQFVIDDYGRVMTDEGICLDSFRKTSIDGEEIVEGVRKIKMVTCGSQ 600

  Fly   592 SESQRWTIE 600
            ..:|||..|
Mosquito   601 KPNQRWVYE 609

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pgant1	NP_611043.1	pp-GalNAc-T	152..461	CDD:133004	152/314 (48%)
		beta-trefoil_Ricin_Pgant1-like	468..601	CDD:467337	30/176 (17%)
Pgant3	XP_317241.5	None