Protein Alignment Pgant1 and Pgant7

DIOPT Version :10

• Sequence 1: NP_611043.1
• Gene: Pgant1 / 36717
• FlyBaseID: FBgn0034025
• Length: 601
• Species: Drosophila melanogaster
• Sequence 2: XP_311182.4
• Gene: Pgant7 / 1272432
• VectorBaseID: AGAMI1_002898
• Length: 598
• Species: Anopheles gambiae
• Alignment Length: 619
• Identity: 210/619 - (33%)
• Similarity: 311/619 - (50%)
• Gaps: 80/619 - (12%)

  Fly    12 LIIFILVALCFILYSKVQQNGSPEEPPVAPLVRAAALRGHGRERFEAYSDSENEIARPATQSPYE 76
            |.|.|::......:|.|..:...:    |...|.||:||||.:    ..:.|.:...|      :
Mosquito    18 LAIVIMILYMIATWSGVDHHTVKD----AYNARLAAMRGHGGD----VGNGEQDRNHP------K 68

  Fly    77 QIIQL--------DLQKQKV-GLGEQGVAVHLSGAAKERGDEIYKKIALNEELSEQLTYNRSVGD 132
            ::.||        ...|..| |.||.|.|..|....:.|..:...:..:|..:|:.::.:|::.|
Mosquito    69 EVPQLVEGLGNFEPADKPMVDGPGEGGKAYVLPEDQQNRATDAEMEYGMNIVVSDAISLDRTIKD 133

  Fly   133 HRNPLCAKQRFDSD-SLPTASVVIIFFNEPYSVLLRTVHSTLSTCNEKALKEIILVDDGSDNVEL 196
            .|...|  :.:|.. .||..||||:|.||.:|||:|||||.|:...:..|.|||||||.||..:|
Mosquito   134 TRLEEC--KHWDYPYHLPRTSVVIVFHNEGFSVLMRTVHSVLNRSPKHLLHEIILVDDYSDKEDL 196

  Fly   197 GAKLDYYVRTRIPSGKVTILRLKNRLGLIRARLAGARIATGDVLIFLDAHCEGNIGWCEPLLQRI 261
            ..||:.|:...  .|.|.::|...|.||||.|..||:.|||:|:::||||||.|..|..|||..|
Mosquito   197 KGKLERYIERF--DGMVRLIRNSEREGLIRTRSRGAKEATGEVIVYLDAHCEVNTNWLPPLLAPI 259

  Fly   262 KESRTSVLVPIIDVIDANDFQYSTNGYKSFQVGGFQWNGHFDW------INLPEREKQRQRRECK 320
            ...||.:.|||||.||...|:     |:.....|..:.|.|:|      ..:|.||::|::.:.:
Mosquito   260 HRDRTVMTVPIIDGIDHKTFE-----YRPVYADGHHYRGIFEWGMLYKENEVPRREQKRRKHDSE 319

  Fly   321 QEREICPAYSPTMAGGLFAIDRRYFWEVGSYDEQMDGWGGENLEMSFRIWQCGGTIETIPCSRVG 385
                  |..|||.|||||||:|::|.|:|:||..:..|||||.|:||:||||||:||.:||||||
Mosquito   320 ------PYRSPTHAGGLFAINRKFFLELGAYDSGLLVWGGENFELSFKIWQCGGSIEWVPCSRVG 378

  Fly   386 HIFRDFHPYKFPNDRDTH-----GINTARMALVWMDEYINIFFLNRPDLKFHADIGDVTHRVMLR 445
            |::|.|.||.|....:..     .||..|:...|.|.....:|..|..|....|:||::.::.|:
Mosquito   379 HVYRGFMPYNFGKLANKKKGPLITINYKRVIETWFDGPYKEYFYTREPLARFLDMGDISEQLALK 443

  Fly   446 KKLRCKSFEWYLKNI-------YPEKFVPTKDVQGWGKVHAVNSNICLDDLLQNNEKPYNAGLYP 503
            ::|:||||:||:.|:       ||  .:|. :|: ||::..|....|:|.|  ..:.|...||..
Mosquito   444 ERLQCKSFQWYMDNVAYDVLDKYP--MLPA-NVK-WGELQNVGKEKCVDAL--GRQPPAVIGLQQ 502

  Fly   504 C-GKVLQKSQLFSFTNTNVLRNELSCATVQHSESPPYRVVMVPCMENDEFNEQWRYEHQH--IIH 565
            | |:  ..:||........|.....|....:||      :.:........:..|:|:.|.  ::|
Mosquito   503 CHGQ--GHNQLIRLNGAGQLGVGERCIEAYNSE------IKLAFCRLGTVDGPWQYDEQSGTLLH 559

  Fly   566 SNTGMCLDHQGLKSLDDAQVA--PCDPHSESQRW 597
            .....|:.:|.    ...|:|  |||.::..|.|
Mosquito   560 RTHKKCMGYQP----QTRQLALMPCDINNAYQSW 589

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pgant1	NP_611043.1	pp-GalNAc-T	152..461	CDD:133004	141/326 (43%)
		beta-trefoil_Ricin_Pgant1-like	468..601	CDD:467337	31/135 (23%)
Pgant7	XP_311182.4	pp-GalNAc-T	152..459	CDD:133004	141/319 (44%)
		beta-trefoil_Ricin_GALNT7	471..593	CDD:467315	31/135 (23%)