Protein Alignment Pgant1 and Galnt16

DIOPT Version :10

• Sequence 1: NP_611043.1
• Gene: Pgant1 / 36717
• FlyBaseID: FBgn0034025
• Length: 601
• Species: Drosophila melanogaster
• Sequence 2: NP_001074890.1
• Gene: Galnt16 / 108760
• MGIID: 1917754
• Length: 558
• Species: Mus musculus
• Alignment Length: 567
• Identity: 214/567 - (37%)
• Similarity: 303/567 - (53%)
• Gaps: 56/567 - (9%)

  Fly    45 AAALRGHGRERFEAYSDSENE---IARPATQSPYEQIIQLDLQKQKVGLGEQGVAVHLSGAAKER 106
            ||:..|.|.:|.....:...|   |....|.:|.:            |..|:   .:||....:.
Mouse    32 AASSSGRGAQRAGGRPEQLREDRTIPLIVTGTPSK------------GFDEK---AYLSAKQLKP 81

  Fly   107 GDEIYKKIALNEELSEQLTYNRSVGDHRNPLCAKQRFDSDSLPTASVVIIFFNEPYSVLLRTVHS 171
            |::.|::.|.|:..|::|:.:|.:.|.|:..|....:.|| ||..||:|.|.||..|.|||||.|
Mouse    82 GEDPYRQHAFNQLESDKLSSDRPIRDTRHYSCPSLSYSSD-LPATSVIITFHNEARSTLLRTVKS 145

  Fly   172 TLSTCNEKALKEIILVDDGSDNVELGAKLDYYVRTRIPSGKVTILRLKNRLGLIRARLAGARIAT 236
            .|:......::|||||||.|.:.|     |..:.||||  ||..||...|.||||:|:.||.:|.
Mouse   146 VLNRTPASLIQEIILVDDFSSDPE-----DCLLLTRIP--KVKCLRNDKREGLIRSRVRGADVAG 203

  Fly   237 GDVLIFLDAHCEGNIGWCEPLLQRIKESRTSVLVPIIDVIDANDFQYSTNGYKSFQV-GGFQWNG 300
            ..||.|||:|||.|:.|.:|:|||:.|..|.|:.||||||..::|.|..   .|..: |||.|:.
Mouse   204 ATVLTFLDSHCEVNVEWLQPMLQRVMEDHTRVVSPIIDVISLDNFAYLA---ASADLRGGFDWSL 265

  Fly   301 HFDWINLPEREKQRQRRECKQEREICPAYSPTMAGGLFAIDRRYFWEVGSYDEQMDGWGGENLEM 365
            ||.|..:|..:|..:....|      |..:|.:|||:|.||:.:|..:|.||.|||.|||||.|:
Mouse   266 HFKWEQIPLEQKMTRTDPTK------PIRTPVIAGGIFVIDKSWFNHLGKYDAQMDIWGGENFEL 324

  Fly   366 SFRIWQCGGTIETIPCSRVGHIFRDFHPYKFPNDRD-THGINTARMALVWMDEYINIFFLNRPDL 429
            |||:|.|||::|.:|||||||:||..|||.||.... |:..||.|.|.||||||...::..||..
Mouse   325 SFRVWMCGGSLEIVPCSRVGHVFRKRHPYNFPEGNALTYIRNTKRTAEVWMDEYKQYYYEARPSA 389

  Fly   430 KFHADIGDVTHRVMLRKKLRCKSFEWYLKNIYPEKFVPTKDVQGWGKVHAVNSNICLDDLLQNNE 494
            ...| .|.|..|:..|||:.||||.|||:|:|||..||.|:|........||   ||:...||..
Mouse   390 IGKA-FGSVATRIEQRKKMDCKSFRWYLENVYPELTVPVKEVLPGVIKQGVN---CLESQGQNTA 450

  Fly   495 KPYNAGLYPC---GKVLQKSQLFSFTNTNVLRNELSC--ATVQHSESPPYRVVMVPCMENDEFNE 554
            .....|:..|   .|....:|.:.|:: ::::.:..|  ||.....||...|::..| ...|..:
Mouse   451 GDLLLGMGICRGSAKSPPPAQAWLFSD-HLIQQQGKCLAATSTLMSSPGSPVILQTC-NPKEGKQ 513

  Fly   555 QWRYEHQHIIHSNTGMCLDHQGLKSLDDAQV--APCDPHSESQRWTI 599
            :||.:...|.||.:|:||:.:      .||:  :.|...:::|:|.:
Mouse   514 KWRRKGSFIQHSVSGLCLETK------PAQLVTSKCQTDAQAQQWQL 554

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pgant1	NP_611043.1	pp-GalNAc-T	152..461	CDD:133004	148/310 (48%)
		beta-trefoil_Ricin_Pgant1-like	468..601	CDD:467337	34/139 (24%)
Galnt16	NP_001074890.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	34..53		3/18 (17%)
		Catalytic subdomain A	122..227		55/111 (50%)
		pp-GalNAc-T	126..420	CDD:133004	148/310 (48%)
		Catalytic subdomain B	286..348		36/61 (59%)
		beta-trefoil_Ricin_GALNT16	426..557	CDD:467357	35/140 (25%)