Protein Alignment Pgant1 and Galnt7

DIOPT Version :10

• Sequence 1: NP_611043.1
• Gene: Pgant1 / 36717
• FlyBaseID: FBgn0034025
• Length: 601
• Species: Drosophila melanogaster
• Sequence 2: NP_653332.3
• Gene: Galnt7 / 108150
• MGIID: 1349449
• Length: 657
• Species: Mus musculus
• Alignment Length: 602
• Identity: 196/602 - (32%)
• Similarity: 291/602 - (48%)
• Gaps: 97/602 - (16%)

  Fly    23 ILYSKVQQNGSPEEPPVAPLVRAAALRGHGRERFEAYSDSENEIARPATQSP-YEQIIQLDLQKQ 86
            :|...|..|..|:||           ..||      ......|.|:|....| |:|.:|..:
Mouse   126 VLRPGVLGNFEPKEP-----------EPHG------VVGGPGEKAKPLVLGPEYKQAVQASI--- 170

  Fly    87 KVGLGEQGVAVHLSGAAKERGDEIYKKIALNEELSEQLTYNRSVGDHRNPLCAKQRFDSDSLPTA 151
                                     |:...|...|:.::.:|||.|.|...|....:| ::|.|:
Mouse   171 -------------------------KEFGFNMVASDMISLDRSVNDLRQEECKYWHYD-ENLLTS 209

  Fly   152 SVVIIFFNEPYSVLLRTVHSTLSTCNEKALKEIILVDDGSDNVELGAKLDYYVRTRIPSGKVTIL 216
            ||||:|.||.:|.|:|||||.:.....|.|.||:|:||.|:...|..|||.|:  ::.:|.|.:.
Mouse   210 SVVIVFHNEGWSTLMRTVHSVIKRTPRKYLAEIVLIDDFSNKEHLKEKLDEYI--KLWNGLVKVF 272

  Fly   217 RLKNRLGLIRARLAGARIA-TGDVLIFLDAHCEGNIGWCEPLLQRIKESRTSVLVPIIDVIDAND 280
            |.:.|.|||:||..||:.| .|.|||:||||||..:.|..||:..|.:.||...|||||||..|.
Mouse   273 RNERREGLIQARSIGAQKAKLGQVLIYLDAHCEVAVNWYAPLVAPISKDRTICTVPIIDVISGNT 337

  Fly   281 FQYSTNGYKSFQVGGFQ-------WNGHFDWINLPEREKQRQRRECKQEREICPAYSPTMAGGLF 338
            ::....|      ||.:       |:....|..:|...::::.|:.|.|    |..||.||||||
Mouse   338 YEIIPQG------GGDEDGYARGAWDWSMLWKRVPLTSREKRLRKTKTE----PYRSPAMAGGLF 392

  Fly   339 AIDRRYFWEVGSYDEQMDGWGGENLEMSFRIWQCGGTIETIPCSRVGHIFR-----DFHPYKFPN 398
            ||::.:|:|:|.||..:..|||||.|:|::||||||.:..:||||||||:|     ...|..:..
Mouse   393 AIEKDFFFELGLYDPGLQIWGGENFEISYKIWQCGGKLLFVPCSRVGHIYRLEGWQGNPPPLYVG 457

  Fly   399 DRDTHGINTARMALVWMDEYINIFFLNRPDLKFHADIGDVTHRVMLRKKLRCKSFEWYLKNI--- 460
            ...|.. |..|:..||.|||.:.|:.:||:.| ....||::.....|:...||||:|:::.|
Mouse   458 SSPTLK-NYVRVVEVWWDEYKDYFYASRPESK-ALPYGDISELKKFREDHNCKSFKWFMEEIAYD 520

  Fly   461 ----YPEKFVPTKDVQGWGKVHAVNSNICLDDLLQNNEKPYNAGLYPCGKVLQKSQLFSFTNTNV 521
                ||   :|.::|: ||::..:.:..|:|.:.:.|......|  ||.: :..:|||.....|.
Mouse   521 ITAHYP---LPPRNVE-WGEIRGLETAYCIDSMGKTNGGFVELG--PCHR-MGGNQLFRINEANQ 578

  Fly   522 LRNELSCATVQHSESPPYRVVMVPCMENDEFNEQWRY--EHQHIIHSNTGMCLDHQGLKSLDDAQ 584
            |.....|.|    :.|....||:.....:||.| |:|  ......|..:|.|||..  :.|....
Mouse   579 LMQYDQCLT----KGPDGSKVMITHCNLNEFKE-WQYFKSLHRFTHITSGKCLDRS--EVLHQVF 636

  Fly   585 VAPCDPHSESQRWTIEH 601
            ::.||....:|:|.:.:
Mouse   637 ISTCDSSKMTQKWEMNN 653

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pgant1	NP_611043.1	pp-GalNAc-T	152..461	CDD:133004	132/328 (40%)
		beta-trefoil_Ricin_Pgant1-like	468..601	CDD:467337	34/134 (25%)
Galnt7	NP_653332.3	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	30..66
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	83..105
		Catalytic subdomain A	206..317		54/112 (48%)
		pp-GalNAc-T	210..518	CDD:133004	131/321 (41%)
		Catalytic subdomain B	381..443		37/61 (61%)
		beta-trefoil_Ricin_GALNT7	530..653	CDD:467315	34/133 (26%)