DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Pgant1 and galnt5

DIOPT Version :9

Sequence 1:	NP_611043.1	Gene:	Pgant1 / 36717	FlyBaseID:	FBgn0034025	Length:	601	Species:	Drosophila melanogaster
Sequence 2:	XP_017953060.2	Gene:	galnt5 / 101733275	XenbaseID:	XB-GENE-950717	Length:	1073	Species:	Xenopus tropicalis

Alignment Length:	570	Identity:	215/570 - (37%)
Similarity:	310/570 - (54%)	Gaps:	76/570 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly    63 ENEIARPATQSPYEQIIQLD---LQKQKVGLGEQG--VAV--HLSGAAKERGDEIYKKIALNEEL 120
            ::|.|:|.:...: :::.:|   ..:.....|:.|  |||  ...|.|:.|    :::...|..|
Frog   543 DHEPAKPRSNKMH-KVVPIDRTMSPRDPNAPGQLGRPVAVPEDKQGEAQSR----WREGHFNVYL 602

  Fly   121 SEQLTYNRSVGDHRNPLCAKQRFDSDSLPTASVVIIFFNEPYSVLLRTVHSTLSTCNEKALKEII 185
            |:.:..:|::.|.|...|:.|.. .|.|||.|::|.|.:|.:|.|:|:|:|.|:...|..:||||
Frog   603 SDLIPLDRAIQDTRPEGCSNQLI-HDDLPTTSIIICFIDEVWSTLMRSVYSVLNRSPEHLIKEII 666

  Fly   186 LVDDGSDNVELGAKLDYYVRTRIPSGKVTILRLKNRLGLIRARLAGARIATGDVLIFLDAHCEGN 250
            ||||.|....|..|||.||: ::|  ||.:|.|..|.||||||:|||.||||:||.|||:|.|.|
Frog   667 LVDDFSTRDYLKEKLDTYVK-KLP--KVRVLHLPERHGLIRARIAGANIATGEVLTFLDSHVECN 728

  Fly   251 IGWCEPLLQRIKESRTSVLVPIIDVIDANDFQYSTNGYKSFQVGGFQWNGHFDWINLPEREKQRQ 315
            :||.||||::::.:|..|..|:|:||.|.|..|.|  .:|||.|.|.|..:|.|..:.....||.
Frog   729 VGWLEPLLEQVRINRRKVACPVIEVISALDLSYMT--VESFQRGVFTWPLNFGWKAMLPEVIQRD 791

  Fly   316 RRECKQEREICPAYSPTMAGGLFAIDRRYFWEVGSYDEQMDGWGGENLEMSFRIWQCGGTIETIP 380
                 ...|:.|...|.||||||:|::.||:|:|:||..:|.|||||:|:||:||.|||.||.||
Frog   792 -----NITEMDPIKCPVMAGGLFSIEKNYFYELGTYDPGLDVWGGENMEISFKIWMCGGEIEIIP 851

  Fly   381 CSRVGHIFRDFHPYKFPNDR-DTHGINTARMALVWMDEYINIFFLNRPD-LKFHADIGDVTHRVM 443
            |||||||||:.:||.||.|| .|...|..|:|.||:|:|..||:.:... ||:..:|||:|.:..
Frog   852 CSRVGHIFRNDNPYSFPKDRIKTVERNLVRVAEVWLDDYKEIFYGHGQHLLKYLPNIGDLTEQKQ 916

  Fly   444 LRKKLRCKSFEWYLKNIYPEKFVPTKDVQGW------GKVHAV-NSNICLDDLLQNNEKPYNAGL 501
            ||::|:||:|.||:||::|:...|.....|.      .|..|: ||...|:....|
Frog   917 LRERLQCKNFNWYIKNVFPDMGTPLLRATGMLSNPKLRKCLAIENSTFVLESCEGN--------- 972

  Fly   502 YPCGKVLQKSQLFSFTNTNVLRNELSC-ATVQHSESPPYRVVMVPCMENDEFNEQWRYEHQHIIH 565
                   :|||.||:|....:|....| ..|::.:|    ..:.|| :....|::|.::.|...|
Frog   973 -------KKSQQFSYTWLRHIRQGDQCIVPVENEDS----ASLQPC-DYTIVNQRWLHKSQISFH 1025

  Fly   566 SNTGMCLDHQGLKSLDDAQVAPC---DPHS------------ESQRWTIE 600
            |:   ..||..|    |:....|   ||.|            ..|:|..|
Frog  1026 SS---LKDHIML----DSTFITCLEADPESGGLVARECSSLKHYQKWRFE 1068

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Pgant1	NP_611043.1	WcaA	147..426	CDD:223539	141/279 (51%)
		pp-GalNAc-T	152..461	CDD:133004	154/310 (50%)
		Ricin_B_lectin	474..597	CDD:279046	32/145 (22%)
		RICIN	481..599	CDD:238092	31/133 (23%)
galnt5	XP_017953060.2	pp-GalNAc-T	633..934	CDD:133004	154/310 (50%)
galnt5	XP_017953060.2	Ricin_B_lectin	944..1065	CDD:395527	33/148 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D606683at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010