DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Pgant1 and galnt6.1

DIOPT Version :9

Sequence 1:	NP_611043.1	Gene:	Pgant1 / 36717	FlyBaseID:	FBgn0034025	Length:	601	Species:	Drosophila melanogaster
Sequence 2:	XP_002933739.1	Gene:	galnt6.1 / 100497888	XenbaseID:	XB-GENE-983702	Length:	622	Species:	Xenopus tropicalis

Alignment Length:	651	Identity:	240/651 - (36%)
Similarity:	334/651 - (51%)	Gaps:	93/651 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 FRSFYGKL----IIFILVALCFILYSKVQQNGSPEEPPVAPLV-----RAAALRGHGRERFEAYS 60
            ||..||.|    :..:.|...||:: |...||:.::|.:..:|     ....:||       |.:
Frog     4 FRRNYGPLKLAMVGMVYVIFVFIMH-KDAGNGAKDDPWIKNIVVRKDQMLDMMRG-------AMN 60

  Fly    61 DSENEIARPATQSPYEQIIQLDLQKQKVGLGEQGVAVHLS-------------GA---------- 102
            :..:.|......:|.::  :..::::|..|.|......|.             ||
Frog    61 NLNDFIPDLQIMAPVQE--EGPVEEKKSCLPEYYTPAELKPFMERPPQDPNSPGADGKEFKKDTW 123

  Fly   103 ------AKERGDEIYKKIALNEELSEQLTYNRSVG-DHRNPLCAKQRFD-SDSLPTASVVIIFFN 159
                  .||:|   :.|...|...|::::.:|::| |.|.|:|.:|:|. ..||||.||:|:|.|
Frog   124 TEEETKEKEKG---FDKHHFNAFASDRISLHRALGPDTRPPVCIEQKFKRCPSLPTTSVIIVFHN 185

  Fly   160 EPYSVLLRTVHSTLSTCNEKALKEIILVDDGSDNVELGAKLDYYVRT-RIPSGKVTILRLKNRLG 223
            |.:|.|||||:|.|.|.....|||||||||.|::..|..|||.||:. :|    |.|.|.|.|.|
Frog   186 EAWSTLLRTVYSVLYTSPAILLKEIILVDDASEDEYLKEKLDDYVKALQI----VKIARQKERKG 246

  Fly   224 LIRARLAGARIATGDVLIFLDAHCEGNIGWCEPLLQRIKESRTSVLVPIIDVIDANDF------Q 282
            |..|||.||.||||:||.|||||||...||.||||.||.|..|:|:.|.|.:||.|.|      |
Frog   247 LTTARLLGASIATGEVLTFLDAHCECFHGWLEPLLSRIAEDHTAVVSPDIPIIDLNSFEFHKPVQ 311

  Fly   283 YSTNGYKSFQVGGFQWNGHFDWINLPEREKQRQRRECKQEREICPAYSPTMAGGLFAIDRRYFWE 347
            |.    |:...|.|.|:..|.|..:|..||:|::      .|..|..:||.|||||:|.:.||..
Frog   312 YG----KTHNRGNFDWSLTFGWEAIPAAEKERRK------DETYPIKTPTFAGGLFSISKAYFEH 366

  Fly   348 VGSYDEQMDGWGGENLEMSFRIWQCGGTIETIPCSRVGHIFRDFHPYKFPNDRDTHGINTARMAL 412
            :|||||:|:.|||||||||||:|||||.:|.||||.|||:||...|:.||........|..|:|.
Frog   367 IGSYDEEMEIWGGENLEMSFRVWQCGGQLEIIPCSVVGHVFRTKSPHTFPKGTQVIFRNLVRLAE 431

  Fly   413 VWMDEYINIFF-LNRPDLKF--HADIGDVTHRVMLRKKLRCKSFEWYLKNIYPEKFVPTKDVQGW 474
            ||||:|..::: .|....|.  ....||::.|:.|:..|:||:|.|||:|||||.|||.:|...:
Frog   432 VWMDDYKLLYYQRNEQAAKMVREKSFGDISKRLKLKADLQCKNFTWYLENIYPEMFVPDRDPTYY 496

  Fly   475 GKVHAVNSNICLDDLLQNN-EKPYNAGLYPCGKVLQKSQLFSFTNTNVLRNELSCATVQHSESPP 538
            |||....|..|||...:|: .||....|  |.. :..:|.|.::....||:.::......|:..|
Frog   497 GKVKNEGSQNCLDAGEKNHGGKPLIMNL--CNG-MGGTQYFEYSTHKELRHNIAKQLCLRSKYVP 558

  Fly   539 YRVVMVPCMENDE-----FNEQWRYEHQHIIHSNTG--MCLDHQGLKSLDDAQVAPCDPHSESQR 596
            ..|.:..|....:     .||:|......:: .|.|  |||..:|    ::...|.|:|....||
Frog   559 GPVELGECQYKGKRTTVPGNEEWELTKDRLL-KNVGSNMCLTARG----ENPSTAECNPSDIHQR 618

  Fly   597 W 597
            |
Frog   619 W 619

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Pgant1	NP_611043.1	WcaA	147..426	CDD:223539	145/286 (51%)
		pp-GalNAc-T	152..461	CDD:133004	155/318 (49%)
		Ricin_B_lectin	474..597	CDD:279046	33/130 (25%)
		RICIN	481..599	CDD:238092	32/125 (26%)
galnt6.1	XP_002933739.1	pp-GalNAc-T	178..483	CDD:133004	155/318 (49%)
galnt6.1	XP_002933739.1	Ricin_B_lectin	496..619	CDD:366226	33/130 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D261568at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010