Protein Alignment Pgant1 and galnt6.2

DIOPT Version :10

• Sequence 1: NP_611043.1
• Gene: Pgant1 / 36717
• FlyBaseID: FBgn0034025
• Length: 601
• Species: Drosophila melanogaster
• Sequence 2: XP_031753046.1
• Gene: galnt6.2 / 100486937
• XenbaseID: XB-GENE-1000674
• Length: 623
• Species: Xenopus tropicalis
• Alignment Length: 645
• Identity: 226/645 - (35%)
• Similarity: 331/645 - (51%)
• Gaps: 78/645 - (12%)

  Fly     5 FRSFYGKL----IIFILVALCFILYSKVQQNGSPEEPPVAPLV-----RAAALRGHGRERFEAYS 60
            ||..||.|    :..:.|...||::..: .||:.::|.:..:|     ....:||       |..
 Frog     4 FRRNYGPLKLAMVGMVFVIFVFIMHKDI-GNGAKDDPWIKNIVVRKDQMINMMRG-------AMK 60

  Fly    61 DSENEIARPATQSPYEQIIQLDLQK-----------------------QKVGLGEQGVAVHL--- 99
            :.::.|.:....:|.:::..::.:|                       ...|...:|...::
 Frog    61 NLKDSIPKLQIMAPVQEVRPVEEKKSCLPGYYTPAELKPFMERPPQDPNSPGADGKGFIKNIWTE 125

  Fly   100 -SGAAKERGDEIYKKIALNEELSEQLTYNRSVGDHRNPL-CAKQRFD-SDSLPTASVVIIFFNEP 161
             ....||:|   :.|...|...|::::.:|::|....|| |.:|:|. ..||||.|::|:|.||.
 Frog   126 EEVEEKEKG---FDKHCFNAFASDRISLHRALGPDTRPLECIEQKFKRCPSLPTTSIIIVFHNEA 187

  Fly   162 YSVLLRTVHSTLSTCNEKALKEIILVDDGSDNVELGAKLDYYVRT-RIPSGKVTILRLKNRLGLI 225
            :|.|||||:|.|.|.....|||||||||.|::..|..|||.||:. :|    |.|.|.|.|.|||
 Frog   188 WSTLLRTVYSVLYTSPAILLKEIILVDDASEDEYLKEKLDDYVKALQI----VKIARQKERKGLI 248

  Fly   226 RARLAGARIATGDVLIFLDAHCEGNIGWCEPLLQRIKESRTSVLVPIIDVIDANDFQYS--TNGY 288
            .|||.||.||||:||.|||||||...||.||||.|:.|..|:|:.|.|..|:.|.|::.  ....
 Frog   249 TARLLGASIATGEVLTFLDAHCECFHGWLEPLLSRVAEDHTAVVSPDITAINYNTFEFGKPVQQG 313

  Fly   289 KSFQVGGFQWNGHFDWINLPEREKQRQRRECKQEREICPAYSPTMAGGLFAIDRRYFWEVGSYDE 353
            |....|.|.|:..|:|..:|..: ::||::     |..|..:||.|||||:|.:.||..:|||||
 Frog   314 KMNSRGNFDWSLAFNWEAIPAAD-EKQRKD-----ETYPIKTPTFAGGLFSISKAYFEHIGSYDE 372

  Fly   354 QMDGWGGENLEMSFRIWQCGGTIETIPCSRVGHIFRDFHPYKFPNDRDTHGINTARMALVWMDEY 418
            :|:.|||||:|||||:|||||.:|.||||.|||:||...|:.||........|..|:|.||||:|
 Frog   373 EMEIWGGENVEMSFRVWQCGGKLEIIPCSVVGHVFRTKSPHTFPKGTQVILRNQVRLAEVWMDDY 437

  Fly   419 INIFFLNRPD----LKFHADIGDVTHRVMLRKKLRCKSFEWYLKNIYPEKFVPTKDVQGWGKVHA 479
             .:.:..|.:    :......||::.|:.|:..|:||:|.|||:|||||.|||.:|...:|.:..
 Frog   438 -KVLYYRRNEQAAKIAKEKSFGDISKRLKLKADLQCKNFTWYLENIYPEMFVPDRDPTYYGAIKN 501

  Fly   480 VNSNICLDDLLQNNEKPYNAGLYPCGKVLQKSQLFSFTNTNVLRNELSCATVQHSESPPYRVVMV 544
            ..:..|:|....||.......:||| ..:..:|.|.::....||:.|.......|:..|..|.:|
 Frog   502 EGTQNCIDVGENNNYGSQLPIMYPC-HGMGGNQYFEYSTHKELRHNLKTQLCLCSKYEPGPVKLV 565

  Fly   545 PCMENDE-----FNEQWRYEHQHIIHS-NTGMCLDHQGLKSLDDAQVAPCDPHSESQRWT 598
            .|....:     .||:|.:....:|.: .:.|||..||    |....|.|:|....|.|:
 Frog   566 DCQYKGQNTTVPGNEEWEFTKDRLIRNVGSNMCLTAQG----DHPSTAECNPDDIDQLWS 621

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pgant1	NP_611043.1	pp-GalNAc-T	152..461	CDD:133004	148/315 (47%)
		beta-trefoil_Ricin_Pgant1-like	468..601	CDD:467337	34/137 (25%)
galnt6.2	XP_031753046.1	pp-GalNAc-T	178..483	CDD:133004	148/315 (47%)
		beta-trefoil_Ricin-like	493..623	CDD:483949	33/134 (25%)