Protein Alignment Pgant1 and galnt3

DIOPT Version :10

• Sequence 1: NP_611043.1
• Gene: Pgant1 / 36717
• FlyBaseID: FBgn0034025
• Length: 601
• Species: Drosophila melanogaster
• Sequence 2: XP_021334717.1
• Gene: galnt3 / 100331984
• ZFINID: ZDB-GENE-120313-1
• Length: 625
• Species: Danio rerio
• Alignment Length: 632
• Identity: 220/632 - (34%)
• Similarity: 323/632 - (51%)
• Gaps: 74/632 - (11%)

  Fly    12 LIIFILVALCFILYSKVQQNGSPEEPPVAPLV-RAAALRGHGRERFEAYSDS--ENEIARPATQ- 72
            ::..:.|...|::..:|......:||.:..:| :...:.|........:.|:  :.:|..|..|
Zfish    19 IVALVFVTFLFLMQREVVSQSPQDEPWLRGIVEKRDGVLGMVMGAVNNFRDAMPKMQIKAPVRQQ 83

  Fly    73 -------------SPYEQIIQLDLQKQKVGL-GEQGVAVHLSGAA------KERGDEIYKKIALN 117
                         :|.|....|:...|.... |..|.|.|....:      ||||:|   |...|
Zfish    84 ESQGSSACLSGYYTPAELKPVLERPPQNPSAPGASGKAFHTDNLSSSEQKEKERGEE---KHCFN 145

  Fly   118 EELSEQLTYNRSVG-DHRNPLCAKQRF-DSDSLPTASVVIIFFNEPYSVLLRTVHSTLSTCNEKA 180
            ...|::::.:|.:| |.|.|.|.:|.| ....|||.||:|:|.||.:|.|||||:|.|.|.....
Zfish   146 LYASDRISLSRDLGPDTRPPECIEQTFRRCPPLPTTSVIIVFHNEAWSTLLRTVYSVLHTSPALF 210

  Fly   181 LKEIILVDDGSDNVELGAKLDYYVR-TRIPSGKVTILRLKNRLGLIRARLAGARIATGDVLIFLD 244
            |||||||||.|.:..|..|||.::: ..|    |.::|...|.|||.|||.||.:||||.|.|||
Zfish   211 LKEIILVDDASVDEHLKDKLDEFLKQLHI----VRVVRQHERKGLITARLLGASVATGDTLTFLD 271

  Fly   245 AHCEGNIGWCEPLLQRIKESRTSVLVPIIDVIDANDFQY---STNGYKSFQVGGFQWNGHFDWIN 306
            ||||...||.||||.||.|:.::|:.|.|..||.|.|::   |..| :....|.|.|...|.|..
Zfish   272 AHCECFHGWLEPLLARIAENSSAVVSPDITTIDLNTFEFMKPSPYG-QHHNRGNFDWGLSFGWET 335

  Fly   307 LPEREKQRQRRECKQEREICPAYSPTMAGGLFAIDRRYFWEVGSYDEQMDGWGGENLEMSFRIWQ 371
            ||:.|::|::      .|..|..:||.|||||:|.|.||:.:|||||:|:.|||||:|||||:||
Zfish   336 LPDHERRRRK------DETYPIKTPTFAGGLFSISRDYFYHIGSYDEEMEIWGGENIEMSFRVWQ 394

  Fly   372 CGGTIETIPCSRVGHIFRDFHPYKFPNDRDTHGINTARMALVWMDEYINIFFLNRPD----LKFH 432
            |||.:|.||||.|||:||...|:.||........|..|:|.||||:|..||:.....    .|.|
Zfish   395 CGGQLEIIPCSVVGHVFRTKSPHTFPKGTQVIARNQVRLAEVWMDDYKEIFYRRNQQAAQIAKEH 459

  Fly   433 ADIGDVTHRVMLRKKLRCKSFEWYLKNIYPEKFVPTKDVQGWGKVHAVNSNICLDDLLQNNEKPY 497
            : .|||:.||.||::|:||||.|||||:|||.|:|..:...:|.:..:....|| |:.::||...
Zfish   460 S-FGDVSRRVDLRERLQCKSFSWYLKNVYPEVFMPDLNPLQFGAIRNMGKEACL-DVGESNEGGK 522

  Fly   498 NAGLYPCGKVLQKSQLFSFTNTNVLRNEL-----------SCATVQHSESPPYRVVMVPCMENDE 551
            ...:||| ..:..:|.|.::..:.:|:.:           :...::..:...:..:..|
Zfish   523 PLIMYPC-HGMGGNQYFEYSTHHEIRHNIQKELCLDGTDGAMVRLEECQYKGHNTITSP------ 580

  Fly   552 FNEQWRYEHQHIIHSNTG-MCLDHQGLKSLDDAQVAPCDPHSESQRW 597
             .::|......:.::... .||..:.    ::..:.||:|..:.|.|
Zfish   581 -QQKWELREDQLFYNKASKQCLSARP----ENPSLVPCNPDDKYQLW 622

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pgant1	NP_611043.1	pp-GalNAc-T	152..461	CDD:133004	156/316 (49%)
		beta-trefoil_Ricin_Pgant1-like	468..601	CDD:467337	21/142 (15%)
galnt3	XP_021334717.1	pp-GalNAc-T	182..487	CDD:133004	156/316 (49%)
		beta-trefoil_Ricin_GALNT3	496..625	CDD:467346	21/140 (15%)