Protein Alignment Pgant1 and galnt18a

DIOPT Version :10

• Sequence 1: NP_611043.1
• Gene: Pgant1 / 36717
• FlyBaseID: FBgn0034025
• Length: 601
• Species: Drosophila melanogaster
• Sequence 2: NP_001124120.1
• Gene: galnt18a / 100170813
• ZFINID: ZDB-GENE-080723-30
• Length: 609
• Species: Danio rerio
• Alignment Length: 638
• Identity: 194/638 - (30%)
• Similarity: 296/638 - (46%)
• Gaps: 98/638 - (15%)

  Fly    17 LVALCFIL---------------YSKVQQNGSPEEPPVAPLVRAAALRGHGRERFEAYSDSENEI 66
            ||:.|.||               .:.|..||:         |:.|. |.| .::|:  .||:.|.
Zfish    10 LVSTCVILSGMTNILCLLYVGWITNYVSNNGN---------VKVAG-RTH-EKKFD--DDSKGET 61

  Fly    67 ARPATQ-SPYEQIIQLDLQKQKVGLGEQGVAVHLSGA-----AKERGDEIYKKIAL--------N 117
            .|...: ...|.::...:|::.....|....:.||..     ..|.|.| .:|:||        |
Zfish    62 LRIIERLDRLESVVNQHIQEKPQSDIEDSADLSLSETLFAHWGHELGPE-SRKVALRKFQYYGYN 125

  Fly   118 EELSEQLTYNRSVGDHRNPLCAKQRFDSDSLPTASVVIIFFNEPYSVLLRTVHSTLSTCNEKALK 182
            ..||::|:.:|:|.|.|...|....:.: .||..|::.||.||..||:||:|||.:.......||
Zfish   126 AYLSDRLSLDRAVPDLRPDGCRNISYPT-GLPQVSIIFIFVNEALSVILRSVHSVIQRTPAHLLK 189

  Fly   183 EIILVDDGSDNVELGAKLDYYVRTRIPSGK--VTILRLKNRLGLIRARLAGARIATGDVLIFLDA 245
            |||||||.|:|.||...|..:|.......:  :.::..:.:.||||:|::|.|.|:..::...||
Zfish   190 EIILVDDHSNNAELLENLQRFVDETNQQQRDFIKVVHHEKQEGLIRSRVSGWRAASAPIVALFDA 254

  Fly   246 HCEGNIGWCEPLLQRIKESRTSVLVPIIDVIDANDFQYSTNGYKSFQVG--GFQWNGHFDWINLP 308
            |.|.:|||.||:|.||:|.||..:.|..|     :.:|.|...:.:.:.  ||.|.....::|.|
Zfish   255 HVEFSIGWAEPILHRIQEDRTRAISPSFD-----NIKYDTFEIEEYPLSAQGFDWELWCRYLNPP 314

  Fly   309 EREKQRQRRECKQEREICPAYSPTMAGGLFAIDRRYFWEVGSYDEQMDGWGGENLEMSFRIWQCG 373
                   :....|:.:..|..||.:. |.|.:||.||.|:|..||.|:.:||||:|:..|:|.||
Zfish   315 -------KSWWMQKNQTAPIRSPALI-GCFVVDREYFEEIGLLDEGMEVYGGENVELGIRVWLCG 371

  Fly   374 GTIETIPCSRVGHIFRDFHPYKFPNDRDTH-GINTARMALVWMDEYINIFFL--NRPDLKFHADI 435
            |::|.|||||:.||.|...||  ..|..|| ..|..|:|.|||||:.:..::  |.|......||
Zfish   372 GSVEVIPCSRIAHIERAHKPY--TEDLATHVRRNALRVAEVWMDEFKSHVYMAWNIPQQDSGIDI 434

  Fly   436 GDVTHRVMLRKKLRCKSFEWYLKNIYPEKFVPTKDVQGWGKV-HAVNSNICLDDLLQNNEKPYNA 499
            ||:..|..||::||||.|.|:|.|||.| .....|...:|.: :::..::|:|....::..|.
Zfish   435 GDIRDRKALRERLRCKPFSWFLNNIYSE-MRTYMDTIAYGVLRNSLRPDLCVDQGPDSDNIPI-- 496

  Fly   500 GLYPCGKVLQKSQLFSFTNTNVLRNELSCATVQHSE--------SPPYRVVMVPCMENDEFNEQW 556
             ||.|..:  ..|...||::..|.......|:...:        |.| |::......|......|
Zfish   497 -LYICHGL--TPQNVYFTSSQQLHVGGLSPTIDDDDNKCLVDVNSRP-RLLECSYASNKHMKLSW 557

  Fly   557 RYEHQHIIHSNTGMCLDHQGLKSLDDAQVAPCDPHS--------ESQRWTIEH 601
                   :.:..|...:.:..:.|:..:.|..| |.        .||:|||.|
Zfish   558 -------LFTQGGSIQNKKSKRCLELVESADVD-HGYQLVLQKCSSQKWTITH 602

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pgant1	NP_611043.1	pp-GalNAc-T	152..461	CDD:133004	123/315 (39%)
		beta-trefoil_Ricin_Pgant1-like	468..601	CDD:467337	28/149 (19%)
galnt18a	NP_001124120.1	pp-GalNAc-T	159..460	CDD:133004	123/315 (39%)
		beta-trefoil_Ricin-like	463..604	CDD:483949	29/154 (19%)