DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Ir52d and Ir7c

DIOPT Version :9

Sequence 1:	NP_611042.2	Gene:	Ir52d / 36716	FlyBaseID:	FBgn0050464	Length:	594	Species:	Drosophila melanogaster
Sequence 2:	NP_001245572.1	Gene:	Ir7c / 31692	FlyBaseID:	FBgn0029966	Length:	625	Species:	Drosophila melanogaster

Alignment Length:	477	Identity:	100/477 - (20%)
Similarity:	170/477 - (35%)	Gaps:	119/477 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly   172 PIYVDQFRNMQGALLKSITFNLIPGSMAYRDPKT--GQEKHIGYVANLLNNFVEKVNATLDMQVK 234
            |::..:..||.|..:...||...|..:...||||  |:..| |....:..:..|::|.|    :|
  Fly   202 PLFPRKLTNMHGCEMVVATFEHRPYVIIEDDPKTPGGRSIH-GIEGLIFRSLAERMNFT----IK 261

  Fly   235 LHKAGKKT--------SFYNITKWASEDLVDIGMSYAAYFEMTNFDTISYPYLMTSTCFMV--PL 289
            |.:...|.        :|..|.|...:..|:                      :|..|||.  ..
  Fly   262 LVEQKDKNRGEILPDGNFTGILKMMVDGEVN----------------------LTFVCFMYSKAR 304

  Fly   290 PDMMPNSEIYMGIVDPPVLVV----LIAIFCIFSVMLNYIKQRSWRSLSLVNVLLND--ICLRGF 348
            .|:|..|..|...  |.||||    .|:.....:....||   .| |..||:::...  |||...
  Fly   305 SDLMLPSTSYTSF--PIVLVVPSGGSISPMGRLTRPFRYI---IW-SCILVSLIFGFVLICLLKI 363

  Fly   349 LAQP------------FPF---------------PRQSNRKLKLISMLVCFFSVITTTMYTSYLQ 386
            .|.|            .||               |:::..:..|:..|:  .::|....||..|.
  Fly   364 TALPGLRNLVLGRRNRLPFMGMWASLLGGLALYNPQRNFARYILVMWLL--QTLILRAAYTGQLY 426

  Fly   387 SFMWGPPIDPKMCSFADLENSRYKLAIRRYDIEMLRP-FNVSMD----HVVVFDESSQLEYLRDS 446
            ..:....:...:.|.:::....|:..|    :..||. |..||.    |.|:..|.| |..|||.
  Fly   427 LLLQDVEMRSPIKSLSEVLAKDYEFRI----LPALRTIFKDSMPTTNFHAVLSLEES-LYRLRDE 486

  Fly   447 FDDN----YMYP-MSALSWSAFKEQQKLFAFPLFYYSEKLCLKPISFFSFPIRRHLPYRDLFEEH 506
            .|..    .:.| ::...:.:...::.|...|     :.|...|::|:   :|.|..::...:..
  Fly   487 DDPGITVALLQPTVNQFDFRSGPNKRHLTVLP-----DPLMTAPLTFY---MRPHSYFKRRIDRL 543

  Fly   507 MLQQNEFGLSTYWIDRSFSDMVRLKLATMNDFSPPRLEDYIEVSDLSWVFGMYFTGLGISCCCFG 571
            ::.....|:...: .:.:.|.:: :::...:..|..|.        .|...      ||..||.|
  Fly   544 IMAMMSSGIVARY-RKMYMDRIK-RVSKRRNLEPKPLS--------IWRLS------GIFVCCAG 592

  Fly   572 LELLGLPSWTRRLRLTNWLRVR 593
            |.|:.|..:...:..||..|:|
  Fly   593 LYLVALIVFILEILTTNHRRLR 614

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ir52d	NP_611042.2	None
Ir7c	NP_001245572.1	Lig_chan-Glu_bd	225..287	CDD:214911	17/66 (26%)
Ir7c	NP_001245572.1	Lig_chan	343..593	CDD:278489	52/281 (19%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR42643
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	2.010