Protein Alignment Ir52a and Ir40a

DIOPT Version :10

• Sequence 1: NP_611041.2
• Gene: Ir52a / 36715
• FlyBaseID: FBgn0034023
• Length: 599
• Species: Drosophila melanogaster
• Sequence 2: NP_610140.4
• Gene: Ir40a / 35449
• FlyBaseID: FBgn0259683
• Length: 732
• Species: Drosophila melanogaster
• Alignment Length: 741
• Identity: 128/741 - (17%)
• Similarity: 228/741 - (30%)
• Gaps: 264/741 - (35%)

  Fly    65 LRKLEISAVTVPSGSTDYDWSFSTAILILSCGYDAENEENSYTLMKLQRTRRLIY---------- 119
            |::..::.:.:||             |.||.|. .:.|.|.|....|||..|..|
  Fly    43 LQQSSLAILALPS-------------LALSDGV-CQKERNVYLDDFLQRLHRSNYKSVVFSQTEL 93

  Fly   120 ----LEDNSEPESVCMRY----------SLKEQH-----------------------------NI 141
                :|:|.:..:.|:..          ||.::|                             .:
  Fly    94 FFQHIEENLQGANECISLILDEPNQLLNSLHDRHLGHRLSLFIFYWGARWPPSSRVIRFREPLRV 158

  Fly   142 AMVKSDFDQSDTFY-------SCRLFQTPNYVEGHFFKDQ-----PIYIENFQNMRGATIRTVAD 194
            .:|.....::...|       |....|..|:.:|.....|     |..:..:.|.:|.|.|....
  Fly   159 VVVTRPRKKAFRIYYNQARPCSDSQLQLVNWYDGDNLGLQRIPLLPTALSVYANFKGRTFRVPVF 223

  Fly   195 SLVP-------RTILYRDE--------KSGETKMMGYLGH-MINTYAQKLNAKLHFID------- 236
            ...|       ......||        :..:.::.|...| ::...::.:|.:..:|:
  Fly   224 HSPPWFWVTYCNNSFEEDEEFNSLDSIEKRKVRVTGGRDHRLLMLLSKHMNFRFKYIEAPGRTQG 288

  Fly   237 --------------TSKLGAKKPSVLDI------MNWVNEDIVD-------------------IG 262
                          |..:|..:....|.      ::|.....::                   :.
  Fly   289 SMRSEDGKDSNDSFTGGIGLLQSGQADFFLGDVGLSWERRKAIEFSFFTLADSGAFATHAPRRLN 353

  Fly   263 TALASSLQFKNMDSVWYPYLLTGYCLMVPVPAKMPYNLVYSMIVDPLVLSIIFVMLCLFSVLII- 326
            .|||....||  ..:|                  |:          |:|:|||.....:.::.:
  Fly   354 EALAIMRPFK--QDIW------------------PH----------LILTIIFSGPIFYGIIALP 388

  Fly   327 YTQHLSWKNLTLANI----------------LLNDK---------------------SLRGLLGQ 354
            |.....|.|..:.::                ||..|                     :||..|.|
  Fly   389 YIWRRRWANSDVEHLGELYIHMTYLKEITPRLLKLKPRTVLSAHQMPHQLFQKCIWFTLRLFLKQ 453

  Fly   355 SFPFPPN--PSKHLKLIIFVLCFASVMITTMYEAYLQSYFTQPPSEPYIRSFRDIGNSSLKMAIS 417
            |.....|  .:|.|.::.::.  |:.::..:|.|.|.|.|.:|..||.|.:.:.:..:.:....
  Fly   454 SCNELHNGYRAKFLTIVYWIA--ATYVLADVYSAQLTSQFARPAREPPINTLQRLQAAMIHDGY- 515

  Fly   418 RLEVNVLTSLNNSHFREISEDHLLIFDDLSEYLVLRDSF--NTSFIFPVSVDRW-----NGYEEQ 475
            ||.|.     ..|...|:.|:...:|..|  |.::|...  :....|..||:..     .|.|::
  Fly   516 RLYVE-----KESSSLEMLENGTELFRQL--YALMRQQVINDPQGFFIDSVEAGIKLIAEGGEDK 573

  Fly   476 QKLFA-EPAFYLATNLCFNQFMLFSPPLRRY--------LPHRHLFEDHMMRQHEFGLV------ 525
            ..|.. |..|:.......|.|.|......||        .|......:.:|:..|.|::
  Fly   574 AVLGGRETLFFNVQQYGSNNFQLSQKLYTRYSAVAVQIGCPFLGSLNNVLMQLFESGILDKMTAA 638

  Fly   526 TFWKSQSFIEMVRLGLASM-----EDLSRKRNEEVSLLLDDISWILKLYLGAMFI--------SS 577
            .:.|....:|..|:...|:     |..||..:.: |.::..::  |::..|| ||        :.
  Fly   639 EYAKQYQEVEATRIYKGSVQAKNSEAYSRTESYD-STVISPLN--LRMLQGA-FIALGVGSLAAG 699

  Fly   578 FCFILEILRCGERCKRLW----RCRW 599
            ...:|||:.......|||    |.:|
  Fly   700 VILLLEIVFIKLDQARLWMLCSRLQW 725

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir52a	NP_611041.2	None
Ir40a	NP_610140.4	Lig_chan-Glu_bd	<265..336	CDD:463166	6/70 (9%)
		Periplasmic_Binding_Protein_Type_2	297..>391	CDD:473866	17/123 (14%)
		Periplasmic_Binding_Protein_Type_2	<496..637	CDD:473866	30/148 (20%)