Protein Alignment CG12964 and mtss1

DIOPT Version :10

• Sequence 1: NP_611040.2
• Gene: CG12964 / 36714
• FlyBaseID: FBgn0034022
• Length: 1129
• Species: Drosophila melanogaster
• Sequence 2: NP_001072800.1
• Gene: mtss1 / 780261
• XenbaseID: XB-GENE-1013322
• Length: 784
• Species: Xenopus tropicalis
• Alignment Length: 771
• Identity: 145/771 - (18%)
• Similarity: 239/771 - (30%)
• Gaps: 240/771 - (31%)

  Fly   154 KDANETLAEEPAQPIVTKKKKKKEKVHVFYVNYKKDQNNKLHLESPIASLNNDDNEEEEEEEEEV 218
            |.|.:.:.::.:..:..:||.||.:..:           :..|:|.:..:|:.....||.|::.|
 Frog   131 KKARQEIKKKSSDTLKLQKKAKKGRGDI-----------QPQLDSAMQDVNDKYLLLEETEKQAV 184

  Fly   219 IQYPVTPLPPVKSTTLRTIIHPDSEKYHSNSG--IHVSFGAEN-KHQTGHILEEHDAESIQRQVV 280
            .:..:....  :..:..:::.|..|:..|..|  .|:...:|: |..|   ::.|...|...||:
 Frog   185 RKALIEERS--RFCSFISMLRPVIEEEISMLGEITHLQTISEDLKMLT---MDPHKLPSASEQVI 244

  Fly   281 ------------ALPPSVSSKSEVSYVSNTRADYGRENNFGSRPGPISNMLFGSNYQQSGINYQQ 333
                        ..||| |..:.:|..|:..:.....|:..||..       ||:......:|:.
 Frog   245 HDLKGSDYNWSYQTPPS-SPSTTMSRKSSVCSSLNSVNSSDSRSS-------GSHSHSPTSHYRY 301

  Fly   334 QQQQLPTQ----------HSNNY-----FRPPSALVGPPPNYPKPAPQQQVQQ------PHRPSI 377
            :...||.|          |.:.:     |:..|         |.|.|.:.|.|      ....|.
 Frog   302 RSSNLPQQAPMRLSSVSSHDSGFISQDAFQSKS---------PSPMPPEAVNQNSSSSASSEASE 357

  Fly   378 TQQQLPSTSSQTIF------------NKLVQQSQFYINHNQQYPQQQHQQQQHQQQHQQQQHQQQ 430
            |.|.:...||.|..            :||
 Frog   358 TCQSVSECSSPTSVSSGSTMGAWASTDKL------------------------------------ 386

  Fly   431 QHQQQHQYQQQHQHQHHQAPQQHQQQAPQQQQYQKPPHKQVQVPFF-PTIPPKSVTPAPYQPVKF 494
                      .:.:.|:..|   ...||    ....|:....:|.. |.....|..|..:.....
 Frog   387 ----------SNGYCHYSLP---SDMAP----VSAGPYSHFPLPASRPWTRSSSALPECHHYYTI 434

  Fly   495 RP--TPAPVAP-----AKPVPLPVKLDNANYQQQQQQHYQPQQQQKLPHQQQSYQFVRQPQFVQQ 552
            .|  .|:...|     |||.|         |.|......|.::::..|.:.   ..:..|..:.:
 Frog   435 GPGMLPSSKVPSWKDWAKPGP---------YDQPMVNTLQRRKREADPSRG---ALITTPGHIDE 487

  Fly   553 PQFVVRSPTPPPEYYSQQKQQTQQQHHQSALN-----YFDIKPSKETELLKSIPKFEQHITETVQ 612
            |.....:|.|..   .:|.::.:..:.:.||.     ..|.:.|....|..|.....|..|....
 Frog   488 PPVPRNTPVPAA---LRQGEEAEATNEELALALSRGLQLDTQRSSRDSLQCSSGYSTQTTTPCCS 549

  Fly   613 NPIATAQQPQQQYHQ---QQVQQQQQFGYSST--RNEVIHDV---------PAPNLG-PTAQQHI 662
            .....:|.....|..   .|..:||.|..|||  ||..|...         ||...| |.|...:
 Frog   550 EDTIPSQVSDYDYFSVSGDQEGEQQDFDKSSTIPRNSDISQSYRRMFQAKRPASTAGLPAAFGPV 614

  Fly   663 SGHYITAGSSGVQQSQQFGSFPSASPTQPPVYAESTHGQKVMVVTPVPP---------------- 711
               .:|.|.:.::::      ||   |:|.|...:..|..:.:.|||.|
 Frog   615 ---IVTPGVATIRRT------PS---TKPSVRRGTIGGGPIPIKTPVIPVKTPTVPDLPGGLPSG 667

  Fly   712 -SSNYVTYSQYSQTANE-PVVHINAQSAALQAQASTNFAQQPRQPASSLISAPSTDNSPFSVSTY 774
             |.:|...|..|..|.| |.:..:..|:....|||.|    |..|.:
 Frog   668 LSEDYGEQSPDSPCATESPTLISDMPSSLWSGQASVN----PPVPGT------------------ 710

  Fly   775 HSDVFKELEQ-RNQKDKKVSQQVQQQAQQIAAAPASASVPAPTSTPATAPNGKASQ 829
            ...|.::..| |.:.|::..:||......          |...:.||.|..|:|.|
 Frog   711 QGFVLEDQRQTRAENDEEEGEQVYSPTFD----------PMVQTDPAVAEPGEAVQ 756

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12964	NP_611040.2	None
mtss1	NP_001072800.1	I-BAR_IMD_MIM	7..237	CDD:153327	22/121 (18%)
		WH2_MTSS1	753..783	CDD:409203	2/4 (50%)
		actin-binding sequence	770..773	CDD:409203