Protein Alignment CG12964 and mtss1lb

DIOPT Version :10

• Sequence 1: NP_611040.2
• Gene: CG12964 / 36714
• FlyBaseID: FBgn0034022
• Length: 1129
• Species: Drosophila melanogaster
• Sequence 2: XP_017212571.1
• Gene: mtss1lb / 564555
• ZFINID: ZDB-GENE-140718-4
• Length: 791
• Species: Danio rerio
• Alignment Length: 779
• Identity: 132/779 - (16%)
• Similarity: 224/779 - (28%)
• Gaps: 253/779 - (32%)

  Fly   146 EPIIEIIIKDANE--TLAEEPAQPIVTKKKKKKEKVHVFYVNYKKDQNNK--------LHLESPI 200
            :|.::..::|.|:  .|.||..:..|.:...::......::::.:...|.        .||::.|
Zfish   163 QPQLDSAMQDVNDMYLLMEETEKQAVRRALVEERGRFCTFISFLQPVVNGEIAMLGEITHLQAII 227

  Fly   201 ASLN--NDDNEEEEEEEEEVIQ----------YPVTPLPPVKSTTLRTIIHPDSEKYHSNSGIHV 253
            ..|.  ..|..:.....|:||:          |...|..|..|.:.::.:.......||::.  .
Zfish   228 DDLTVLTSDPHKLPPASEQVIKDLKGSDYSWSYQTPPSSPSSSGSRKSSMCSSVNSAHSSAS--R 290

  Fly   254 SFGAENKHQ----------------TGHIL---EEHDAESIQR--QVVALPPSVSSKSEVSYVSN 297
            |.|....|.                ..|.|   ..||:..|.:  .|.:.|||.......|..|:
Zfish   291 SSGGSQTHSPSSSCRYRSLAQPLTTAAHRLSSVSSHDSGFISQDANVYSKPPSPMPSDITSQKSS 355

  Fly   298 TRADYGRENNFGSRPGPISNMLFGSNYQQSGINYQQQQQQLPTQHSNNYFRPPSALVGPPPNYPK 362
            :.|.........|.....|...|||::...          .|........||.|.::...|.|.:
Zfish   356 SSASSEASETCQSVSECSSPTTFGSSFATF----------RPALSHTGSIRPFSVILPASPPYNR 410

  Fly   363 ------PAPQQQVQQPHRPSITQQQLPSTSSQTIFNKLVQQSQFYINHNQQYPQQQHQQQQHQQQ 421
                  |:|..:|     |.........:|.|.:.:.|
Zfish   411 SPGSNTPSPTSKV-----PCWKDWSKVGSSDQPLASTL--------------------------- 443

  Fly   422 HQQQQHQQQQHQQQHQYQQQHQHQHHQAPQQHQQQAPQQQQYQKPPHKQVQVPFFPTIPPKSVTP 486
                                   |..:.|.  .:.:||.|.|.:.|.:       |.:.|.::..
Zfish   444 -----------------------QRRKEPV--AETSPQSQGYSEDPQR-------PRMTPATIAA 476

  Fly   487 APYQPVKFRPTPAPVAPAKPVPLPVKLDNANYQQQQQQH---YQPQ------QQQKLPHQQQSYQ 542
            ...:.|    :||....|..:...:.::.....:...|:   |..|      .:..:|.|...|.
Zfish   477 KHGEEV----SPAASDLAMVLTRGLSMEQQKSSRDSLQYSSGYSTQTTTPSCSEDTIPSQGSDYD 537

  Fly   543 FVRQPQFVQQPQFVVRSPTPPPEYYSQQKQQTQQQHHQSALNYFDIKPSKETELLKSIPKFEQHI 607
                       .:.|...|.........|..|..:|...|.||                   :.:
Zfish   538 -----------GYSVNGDTEADGQAEFDKSSTIPRHSNIAQNY-------------------RRM 572

  Fly   608 TETVQNPIATAQQPQQQYHQQQVQQQQQFGYSSTRNEVIHDVPAPNLGPTAQQHISGHYITAGSS 672
            .:| :.|.:||..|.              |..:..            ||           ..|..
Zfish   573 IQT-KRPASTAGLPS--------------GVGALG------------GP-----------PGGGG 599

  Fly   673 GVQQSQQFGSFPSAS-------------PTQPPVYAESTHGQKVMVVTPVPPSSNYVTYSQYSQT 724
            |:..:......||..             |.:||:         |.|.||..|.|...:....::.
Zfish   600 GIPGTATIRRTPSTKPGVRRTLSNAGPIPIRPPI---------VPVKTPTVPDSPGGSTGPPARV 655

  Fly   725 ANEPVVHI---NAQSAALQ-AQASTNFAQQPRQPASSLISAPSTDNSPFSVSTYHSDVFKELEQR 785
            .:|..|..   :|...||: .:||      |::     :|.|:|......|......|:   .|.
Zfish   656 GSEECVFYVPDDASPGALEYVKAS------PKR-----LSLPNTAWGSGGVGGLEMSVY---GQP 706

  Fly   786 NQKDKKVSQQVQQQAQQIAAAPASA------SVPAPTSTPATAPNGKASQTLLQLPDEVPDDLR 843
            .::|..::.......::|....|||      ..|.| |.|...|.|..:|...:...|..|.|:
Zfish   707 GEEDHLLAANRHSLVEKIGELVASAHALGEGQFPFP-SLPNQPPPGPEAQVDPEAAQEEGDMLK 769

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12964	NP_611040.2	None
mtss1lb	XP_017212571.1	I-BAR_IMD_MIM	11..241	CDD:153327	13/77 (17%)
		Herpes_BLLF1	<342..670	CDD:282904	74/482 (15%)
		WH2_MTSS1	760..790	CDD:409203	3/10 (30%)
		actin-binding sequence	777..780	CDD:409203