Protein Alignment SRPK and si:ch211-220i18.4

DIOPT Version :10

• Sequence 1: NP_001369087.1
• Gene: SRPK / 36706
• FlyBaseID: FBgn0286813
• Length: 1009
• Species: Drosophila melanogaster
• Sequence 2: XP_021325577.2
• Gene: si:ch211-220i18.4 / 798392
• ZFINID: ZDB-GENE-090312-151
• Length: 393
• Species: Danio rerio
• Alignment Length: 632
• Identity: 197/632 - (31%)
• Similarity: 269/632 - (42%)
• Gaps: 251/632 - (39%)

  Fly   133 ESYESETFSDNEDQELMEDYCKGGYHPVNIGDLFHDRYHVIRKLGWGHFSTVWLCWDLQAMGYVA 197
            |..|.:...:.||.   .|||.||||||.:||:|:.||.|:.|||||:|||||||.||::..:||
Zfish    12 EHLEPDLAEEFEDP---RDYCYGGYHPVQVGDIFNKRYKVLSKLGWGYFSTVWLCVDLRSGRHVA 73

  Fly   198 IKIVKSAPHFAETARDEIKILKTVRETDPSNPRRHKTVQMLDDFKITGVNGTHICMVFEVLGDNL 262
            :|::||...|.:..:||:.:|:........||.:.:.||:||:||:.||||.|||:|.|:||.:|
Zfish    74 VKVLKSGAGFTQAGQDELTLLRCASGPTARNPLKGRIVQLLDEFKLAGVNGIHICLVLELLGPDL 138

  Fly   263 LKLIRKSNYRGIPLANVKTITRQVLEGLDYLHTCCKIIHTDIKPENVLLCVDEPHVRSLATEATQ 327
            ..........|:.|:.||.:..||||||:|||:.||||||||||||:|||. .||
Zfish   139 RCWQMCFGNPGLSLSCVKHVITQVLEGLEYLHSHCKIIHTDIKPENILLCF-TPH---------- 192

  Fly   328 LYCMNSKMYPSLVSRAPKEYREPPITGKMSKNRKKKLKKKAKKRMELFKQQRDYLEQADGQGAIN 392
                                  ||
Zfish   193 ----------------------PP----------------------------------------- 194

  Fly   393 PNEVQNGDAGISDADEYFDANSVEDNVHVAAGQPSRKQREERKAPPEQSEEAQEQDPLTEGTDKA 457
                 .||
Zfish   195 -----GGD--------------------------------------------------------- 197

  Fly   458 KKKKKKKNKNKSNQSKGQQPPQLENSTSSAESSSALKSQQANGSNSTTNNKSNTNSSGTLKGQSN 522
                                  :...:|||..::.||:...:|...|..|..
Zfish   198 ----------------------IHTYSSSAIRNTVLKAPGESGKLGTWGNLE------------- 227

  Fly   523 GKKMPLRPKQEKQGSNHQLNNNNSKPNSNSDSKISSGSVENTSSATNGPHSNSTLPTPPPPPQAK 587
                                                                             
Zfish   228 ----------------------------------------------------------------- 227

  Fly   588 HKAKKDPALDECNVHVKIADLGNACWVDRHFTEDIQTRQYRSLEVIIGAGYNTSADIWSTACMVF 652
                        ::.|||||||::|||.:||.::|||||||||||::|:.|..:|||||.||:.|
Zfish   228 ------------DITVKIADLGSSCWVYKHFCQEIQTRQYRSLEVLLGSEYGPAADIWSVACLAF 280

  Fly   653 ELATGDYLFEPHSGESYTRDEDHLAHIIELLGPIPREILLNGTYAAKSFTRSCELRNISGLKPWG 717
            ||||||.||||.:|.:::.:||||||||||||.||..:...|.|..:.|.|..:||.|:.|:|||
Zfish   281 ELATGDSLFEPKAGPNFSLEEDHLAHIIELLGKIPVSVAQCGKYYYEYFNRKGDLRRIAVLRPWG 345

  Fly   718 LMDVLLEKYEWSQKDAASFASFLTPMLEFDPNKRATAAECLQHPWLR 764
            |.:||:|||.:..::|:.|:.||..||.:.|.:|||||:||:||||:
Zfish   346 LYEVLVEKYHFLLREASLFSDFLLQMLNYLPERRATAAQCLKHPWLK 392

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SRPK	NP_001369087.1	Protein Kinases, catalytic domain	159..>318	CDD:473864	80/158 (51%)
		Protein Kinases, catalytic domain	<600..763	CDD:473864	91/162 (56%)
si:ch211-220i18.4	XP_021325577.2	None