Protein Alignment SRPK and srpk1b

DIOPT Version :9

• Sequence 1: NP_001369087.1
• Gene: SRPK / 36706
• FlyBaseID: FBgn0286813
• Length: 1009
• Species: Drosophila melanogaster
• Sequence 2: XP_005155715.1
• Gene: srpk1b / 791187
• ZFINID: ZDB-GENE-070112-2292
• Length: 643
• Species: Danio rerio
• Alignment Length: 673
• Identity: 314/673 - (46%)
• Similarity: 406/673 - (60%)
• Gaps: 73/673 - (10%)

  Fly   111 QAKAKPNTQKEHQQQPPRSSSNESYESETFSDNEDQELMEDYCKGGYHPVNIGDLFHDRYHVIRK 175
            :|..:|:.......|.| .:..|..|....||:|:||...||||||||.|.|||||:.|||||||
Zfish    22 RASCRPDPHPRGAAQQP-DALQEQDEEILGSDDEEQEDPNDYCKGGYHHVKIGDLFNGRYHVIRK 85

  Fly   176 LGWGHFSTVWLCWDLQAMGYVAIKIVKSAPHFAETARDEIKILKTVRETDPSNPRRHKTVQMLDD 240
            |||||||||||.||.|...:||:|:||||.|:.|||.||||:||.||.||.::|.|.|.||:|||
Zfish    86 LGWGHFSTVWLAWDTQGKRFVAMKVVKSAEHYTETALDEIKLLKAVRNTDQNDPSREKVVQLLDD 150

  Fly   241 FKITGVNGTHICMVFEVLGDNLLKLIRKSNYRGIPLANVKTITRQVLEGLDYLHTCCKIIHTDIK 305
            |||:||||||:||||||||.:|||.|.||||:|:||..||:|.||||:|||||||.|||||||||
Zfish   151 FKISGVNGTHVCMVFEVLGHHLLKWIIKSNYQGLPLPCVKSIIRQVLQGLDYLHTKCKIIHTDIK 215

  Fly   306 PENVLLCVDEPHVRSLATEATQLYCMNSKMYP---SLVSRAPKEYREPPITGKMSKNRKKKLKKK 367
            |||:|:.|:|.:|:.||.|||:  ...|...|   |.||.||    .|....|||||:|||:|||
Zfish   216 PENILMDVNEAYVKRLAAEATE--WQKSGAPPPSGSAVSTAP----APKQATKMSKNKKKKMKKK 274

  Fly   368 AKKRMELFKQ---QRDYLEQA-DGQGAINPNEVQNGDAGISDADEY----FDANSVEDNVHVAAG 424
            .|::.||.::   :.:.||:. ||....:.:|.:..|:..|....:    ....:..|....|..
Zfish   275 QKRQAELLEKRILEIEGLEKGLDGGEEEDEDETETPDSTPSVPSSHTLQDISTETTLDGTSEAWS 339

  Fly   425 QPSRKQREERKAP-PEQSEEAQEQ-------DPLTEGTDKAKKKKKKKNKNKSNQSKGQQPPQLE 481
            |.:........:| .|||.:.|:|       :|...|.:               .|:...|....
Zfish   340 QVTGSVNGHIPSPEDEQSLDVQQQMKDETPVNPYDSGNE---------------TSEPTNPYPAC 389

  Fly   482 NSTSSAESSSALKSQQANGSNSTTNNKSNTNSSGTLKGQS-NGKKMPLRPKQEKQGSNHQLNNNN 545
            |.|...|.|.|..| .|:|:.:..:....:.......|:| ..:....|.:.|.:.....:   .
Zfish   390 NGTEETEPSPACLS-AADGNGALISGMVESQGCRVQDGESLTAELKDPRAEMEAEPGTQAV---P 450

  Fly   546 SKPNSNSDSKISSGSVENTSSATNGPHSNSTLPTPPPPPQAKHKAKKDPALDECNVHVKIADLGN 610
            .:..|..|:|.::|::               |..|..|..|:            .:.||||||||
Zfish   451 EEEESLKDAKTAAGNL---------------LVNPLEPLNAE------------KIQVKIADLGN 488

  Fly   611 ACWVDRHFTEDIQTRQYRSLEVIIGAGYNTSADIWSTACMVFELATGDYLFEPHSGESYTRDEDH 675
            ||||.:|||:||||||||||||:||.||.|.|||||||||.||||||||||||||||.|:|||||
Zfish   489 ACWVHKHFTDDIQTRQYRSLEVLIGTGYGTPADIWSTACMAFELATGDYLFEPHSGEDYSRDEDH 553

  Fly   676 LAHIIELLGPIPREILLNGTYAAKSFTRSCELRNISGLKPWGLMDVLLEKYEWSQKDAASFASFL 740
            :|.||||||.|||::::||.|:.:.||:..:||:|:.||||||.|||:|||||.:::|.:|:.||
Zfish   554 IALIIELLGKIPRKLVMNGKYSKEFFTKKGDLRHITKLKPWGLQDVLVEKYEWHREEAQNFSDFL 618

  Fly   741 TPMLEFDPNKRATAAECLQHPWL 763
            .|||:..|.|||||||||:|.|:
Zfish   619 LPMLDLIPEKRATAAECLRHSWI 641

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SRPK	NP_001369087.1	PKc_like	159..>318	CDD:419665	113/158 (72%)
		PKc_like	<600..763	CDD:419665	113/162 (70%)
srpk1b	XP_005155715.1	PKc_like	70..>256	CDD:304357	126/191 (66%)
		S_TKc	80..>224	CDD:214567	104/143 (73%)
		PKc_like	<465..641	CDD:304357	117/202 (58%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	255	1.000	Domainoid score	I2009
eggNOG	1	0.900	-	-		E1_KOG1290
Hieranoid	0	0.000	Not matched by this tool.
Homologene	1	1.000	-	-		H110962
Inparanoid	1	1.050	548	1.000	Inparanoid score	I1117
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D290680at2759
OrthoFinder	1	1.000	-	-		FOG0000847
OrthoInspector	1	1.000	-	-		otm26464
orthoMCL	1	0.900	-	-		OOG6_100556
Panther	1	1.100	-	-	LDO	PTHR24055
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2294
SonicParanoid	1	1.000	-	-		X594
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	14	13.860