Protein Alignment SRPK and madd-3

DIOPT Version :9

• Sequence 1: NP_001369087.1
• Gene: SRPK / 36706
• FlyBaseID: FBgn0286813
• Length: 1009
• Species: Drosophila melanogaster
• Sequence 2: NP_001368709.1
• Gene: madd-3 / 3565068
• WormBaseID: WBGene00006517
• Length: 890
• Species: Caenorhabditis elegans
• Alignment Length: 850
• Identity: 147/850 - (17%)
• Similarity: 235/850 - (27%)
• Gaps: 385/850 - (45%)

  Fly    23 RKRGKQNGT--------NPQEQSNSSQNQNPK-------------------PSSNPIPEPNRS-- 58
            |..|.::||        |....|...|..|.|                   |.:..:...::|
 Worm   339 RAYGSKSGTTICAIGSPNVPSTSQPQQGDNEKRLIEKKLSLRKKKLSGEGVPPAGSMLTGSKSGV 403

  Fly    59 ----SENLQAPDNANNSHLNAPSSAAFSKATATATASTSSG-GSAGTPDQ------------YQP 106
                |.||...:|.||........|..:.....|..||.:| |:|.|.|.            .||
 Worm   404 EIGLSSNLTTTNNNNNKEQTDEQRAKKTVNAVAAAFSTQAGSGNATTVDDPASTTTSKENPAAQP 468

  Fly   107 PKKTQA---------------------------KAKPNTQKEHQQQPPRSSSNESYESETFSDNE 144
            ||...|                           ||:..::...|....|....|...|:.....:
 Worm   469 PKPKSAAVQNLISQLQLPASVSAKVDKIIACGDKARKPSRSGLQASQARPKVPEIVSSQRTQHQD 533

  Fly   145 DQELMEDYCKGGYHPVNIGDLFHDRYHVIRKLGWGHFSTVWLCWDLQAMGYVAIKIVKSAPHFAE 209
            |        |.|:...:.||...:|:.:...||.|.|..|....|..:..::|:||:|:...:.|
 Worm   534 D--------KDGHLIYSKGDFILNRFTIYDTLGEGTFGKVVRVNDSLSDTFMALKIIKNVSKYRE 590

  Fly   210 TARDEIKILKTVRETDPSNPRRHKTVQMLDDFKITGVNGTHICMVFEVLGDNLLKLIRKSNYRGI 274
            .|:.|:|:|:.:.|.||.  :::..:.|...|...|    |||::|:::|.::...::.::|:..
 Worm   591 AAKLEVKVLQKLAEKDPE--KKNWVIHMGSYFDYNG----HICLLFDLMGSSIFDFLKANHYKPY 649

  Fly   275 PLANVKTITRQVLEGLDYLHTCCKIIHTDIKPENVLLCVDEPHVRSLATEATQLYCMNSKMYPSL 339
            |:.....||.|:...:.:||. .|:.|||:||||:|. ||..:...|.
 Worm   650 PMEQTLHITWQLCNAVKFLHD-NKLTHTDLKPENILF-VDSRYTTKLV----------------- 695

  Fly   340 VSRAPKEYREPPITGKMSKNRKKKLKKKAKKRMELFKQQRDYLEQADGQGAINPNEVQNGDAGIS 404
                                                                             
 Worm   696 ----------------------------------------------------------------- 695

  Fly   405 DADEYFDANSVEDNVHVAAGQPSRKQREERKAPPEQSEEAQEQDPLTEGTDKAKKKKKKKNKNKS 469
                                                                             
 Worm   696 ----------------------------------------------------------------- 695

  Fly   470 NQSKGQQPPQLENSTSSAESSSALKSQQANGSNSTTNNKSNTNSSGTLKGQSNGKKMPLRPKQEK 534
                                                                  .|.|||..
 Worm   696 ------------------------------------------------------DKKPLRVL--- 703

  Fly   535 QGSNHQLNNNNSKPNSNSDSKISSGSVENTSSATNGPHSNSTLPTPPPPPQAKHKAKKDPALDEC 599
                                                 ||
 Worm   704 -------------------------------------HS-------------------------- 705

  Fly   600 NVHVKIADLGNACWVDRHFTEDIQTRQYRSLEVIIGAGYNTSADIWSTACMVFELATGDYLFEPH 664
             .||::.|.|:|.:...|.:..:.||.||:.|||:..|::...|:||..|:::||.||..||:.|
 Worm   706 -THVRLIDFGSATFDHEHHSIIVSTRHYRAPEVILELGWSQPCDVWSIGCILYELYTGVTLFQTH 769

  Fly   665 SGESYTRDEDHLAHIIELLGPIP-REILLNGTYAAKSFTRSCELRNISGLKPWGLMDV------- 721
                  .:.:|||.:..:||.|| |......|:..|.|        |:|...|.....
 Worm   770 ------ENREHLAMMERVLGDIPLRMAKRTNTFRTKFF--------INGRLDWVNTSADAAYVRD 820

  Fly   722 ----LLEKYEWSQKDAASFASFLTPMLEFDPNKRATAAECLQHPWLRX--DTMQPGCWLRATQPA 780
                |......:..:.......:..||.|:|..|....|.|||.:..   :.::..|.:.|:...
 Worm   821 NCKPLRRSMSCTDPEHVELFELIENMLMFEPLARMKLPEALQHRYFNRLPENLKIPCKMDASTNP 885

  Fly   781 TADGD 785
            ..:||
 Worm   886 RINGD 890

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SRPK	NP_001369087.1	PKc_like	159..>318	CDD:419665	47/158 (30%)
		PKc_like	<600..763	CDD:419665	49/174 (28%)
madd-3	NP_001368709.1	PHA03247	<73..364	CDD:223021	6/24 (25%)
		PKc_CLK	538..866	CDD:271036	103/617 (17%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D290680at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.920