Protein Alignment SRPK and srpk1a

DIOPT Version :9

• Sequence 1: NP_001369087.1
• Gene: SRPK / 36706
• FlyBaseID: FBgn0286813
• Length: 1009
• Species: Drosophila melanogaster
• Sequence 2: NP_955944.1
• Gene: srpk1a / 323679
• ZFINID: ZDB-GENE-030131-2399
• Length: 634
• Species: Danio rerio
• Alignment Length: 697
• Identity: 321/697 - (46%)
• Similarity: 420/697 - (60%)
• Gaps: 116/697 - (16%)

  Fly   108 KKTQAKAKPNTQK-------EHQQQPPRSSS--NESYESETFSDNEDQELMEDYCKGGYHPVNIG 163
            :|.:||||.:|:|       ..|||||.:.:  .|..|....||:|:||...||||||||.|.||
Zfish    11 RKKRAKAKKSTKKPAHPPRGASQQQPPPTETQIQEPDEEILGSDDEEQEDPNDYCKGGYHHVKIG 75

  Fly   164 DLFHDRYHVIRKLGWGHFSTVWLCWDLQAMGYVAIKIVKSAPHFAETARDEIKILKTVRETDPSN 228
            ||.:.:|||||||||||||||||.||:|...:||:|:||||.|:.|||.||||:|::||.|||.:
Zfish    76 DLLNSKYHVIRKLGWGHFSTVWLAWDIQGKRFVAMKVVKSAEHYTETALDEIKLLRSVRNTDPDD 140

  Fly   229 PRRHKTVQMLDDFKITGVNGTHICMVFEVLGDNLLKLIRKSNYRGIPLANVKTITRQVLEGLDYL 293
            |.|...||:||||||:||||||:||||||||.:|||.|.||||:|:||..||:|.||||:|||||
Zfish   141 PNREMVVQLLDDFKISGVNGTHVCMVFEVLGHHLLKWIIKSNYQGLPLPCVKSIIRQVLQGLDYL 205

  Fly   294 HTCCKIIHTDIKPENVLLCVDEPHVRSLATEATQLYCMNSKMYP---SLVSRAPKEYREPPITGK 355
            ||.|:||||||||||:|:.|:|.:||.||.|||:  ...:...|   |.||.||...:.|    |
Zfish   206 HTKCQIIHTDIKPENILMSVEELYVRRLAAEATE--WQKAGAPPPSGSAVSTAPAPKQAP----K 264

  Fly   356 MSKNRKKKLKKKAKKRMELFKQQRDYLEQADGQGAINPNEVQNGDAGISDADEYFDANSVEDNVH 420
            ||||:|||||||.|::.||.::....||           |::.|..|
Zfish   265 MSKNKKKKLKKKQKRQAELLEKCIMDLE-----------EMEIGPEG------------------ 300

  Fly   421 VAAGQPSRKQREERKAPPEQSE--------EAQEQDPLTEGTDKAKKKK------KKKNKNKSNQ 471
                      |||.:..||..:        :|..|:..||......:::      .:.|.|....
Zfish   301 ----------REEEEDDPESPKSPSCAPLRQASLQEIATEDIIMDTRERLTSDASVELNCNGCLH 355

  Fly   472 SKGQQPPQLE---------------NSTSSAESSSALKSQQANGSNSTTNNKSNTNSSGTLKGQS 521
            |...||.:.|               |:.:..|.::....:..||:.|...::: ..|:|| .||.
Zfish   356 SSKTQPEEDEQGDLQYGQLLQEDHHNANAGPEDTAQSMYEYCNGAESPELDQA-CYSNGT-SGQE 418

  Fly   522 NGKKMPLRPKQEKQGSNHQLNNNNSKPNSNSDSKISSGSVENTSSATNGPHSNSTLPTPPPPPQA 586
            ..:...|..:::.|..........:| :...|.|:|:||:               |..|..|
Zfish   419 QLEDGELATEEQHQQKTRTRAREQNK-DKIKDDKLSAGSL---------------LVNPLDP--- 464

  Fly   587 KHKAKKDPALDECNVHVKIADLGNACWVDRHFTEDIQTRQYRSLEVIIGAGYNTSADIWSTACMV 651
                     |:...:.||||||||||||.:||||||||||||||||::|:||||.|||||||||.
Zfish   465 ---------LNADKIKVKIADLGNACWVHKHFTEDIQTRQYRSLEVLLGSGYNTPADIWSTACMA 520

  Fly   652 FELATGDYLFEPHSGESYTRDEDHLAHIIELLGPIPREILLNGTYAAKSFTRSCELRNISGLKPW 716
            ||||||||||||||||.|:|||||:|.||||||.:||:::|.|.|:.:.|::..:|::|:.||||
Zfish   521 FELATGDYLFEPHSGEDYSRDEDHIALIIELLGVVPRKLVLTGKYSKEFFSKKGDLKHITKLKPW 585

  Fly   717 GLMDVLLEKYEWSQKDAASFASFLTPMLEFDPNKRATAAECLQHPWL 763
            ||:|||::||||.|::|.:|:.||.||||..|.||||||:||:||||
Zfish   586 GLLDVLMDKYEWPQEEAQTFSDFLLPMLELLPEKRATAADCLRHPWL 632

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SRPK	NP_001369087.1	PKc_like	159..>318	CDD:419665	109/158 (69%)
		PKc_like	<600..763	CDD:419665	112/162 (69%)
srpk1a	NP_955944.1	PKc_like	72..632	CDD:304357	292/634 (46%)
		S_TKc	82..>224	CDD:214567	102/141 (72%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	255	1.000	Domainoid score	I2009
eggNOG	1	0.900	-	-		E1_KOG1290
Hieranoid	0	0.000	Not matched by this tool.
Homologene	1	1.000	-	-		H110962
Inparanoid	1	1.050	548	1.000	Inparanoid score	I1117
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D290680at2759
OrthoFinder	1	1.000	-	-		FOG0000847
OrthoInspector	1	1.000	-	-		otm26464
orthoMCL	1	0.900	-	-		OOG6_100556
Panther	1	1.100	-	-	O	PTHR24055
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X594
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	13	12.830