Protein Alignment Hr51 and Nr2f1

DIOPT Version :10

• Sequence 1: NP_611032.2
• Gene: Hr51 / 36702
• FlyBaseID: FBgn0034012
• Length: 582
• Species: Drosophila melanogaster
• Sequence 2: NP_112392.2
• Gene: Nr2f1 / 81808
• RGDID: 621682
• Length: 420
• Species: Rattus norvegicus
• Alignment Length: 535
• Identity: 166/535 - (31%)
• Similarity: 214/535 - (40%)
• Gaps: 176/535 - (32%)

  Fly    45 APPTQPPPPHPAAPNVPNGRLLSWNHSAAAAAAAAAAQAAANSMNHSSAAEGSSMTRIKGQNLGL 109
            ||.|...|..|.||..|                     ..|..........|.|...|:
  Rat    45 APHTPQTPGQPGAPATP---------------------GTAGDKGQGPPGSGQSQQHIE------ 82

  Fly   110 ICVVCGDTSSGKHYGILACNGCSGFFKRSVRRKLIYRCQAGTGRCVVDKAHRNQCQACRLKKCLQ 174
             ||||||.|||||||...|.||..||||||||.|.|.|:|.. .|.:|:.||||||.|||||||:
  Rat    83 -CVVCGDKSSGKHYGQFTCEGCKSFFKRSVRRNLTYTCRANR-NCPIDQHHRNQCQYCRLKKCLK 145

  Fly   175 MGMNKDAVQNERQPRNTATIRPETLREMEHGRALREAAVAVGVFGPPVLLSPPCYGSGLLPPPSL 239
            :||.::|||..|.|..........|..                 |.|  |:..||.||.:
  Rat   146 VGMRREAVQRGRMPPTQPNPGQYALTN-----------------GDP--LNGHCYLSGYI----- 186

  Fly   240 GSLPTGRLLHHNHLTSSMQLAANHMGAGSFPMFNAAGVHHSPKEKAYGMEMATSGNVSHSTNSSS 304
                            |:.|.|
  Rat   187 ----------------SLLLRA------------------------------------------- 192

  Fly   305 NHSIDPSSPAPENAKEINIAGGSVSSVSSSSPTMENDNDDDSIDVTNDNEEPHAVSRSDSSFIMP 369
                                                              ||:..||..|
  Rat   193 --------------------------------------------------EPYPTSRYGS----- 202

  Fly   370 QFMSPNLYTHQHETVYETSARLLFMAVKWAKNLPSFARLSFRDQVILLEESWSELFLLNAIQWCI 434
            |.|.|| .....|.:.|.:|||||.||:||:|:|.|..|...|||.||..:|||||:|||.|..:
  Rat   203 QCMQPN-NIMGIENICELAARLLFSAVEWARNIPFFPDLQITDQVSLLRLTWSELFVLNAAQCSM 266

  Fly   435 PLDPTGCALFSVAEHCNNLENNANGDTCITKEELAADVRTLHEIFCKYKAVLVDPAEFACLKAIV 499
            ||. ....|.:...|.:.:    :.|..:.   ....:|...|...|.||:.||.||::||||||
  Rat   267 PLH-VAPLLAAAGLHASPM----SADRVVA---FMDHIRIFQEQVEKLKALHVDSAEYSCLKAIV 323

  Fly   500 LFRPETRGLKDPAQIENLQDQAHVMLSQHTKTQFTAQIARFGRLLLMLPLLRMISSHKIESIYFQ 564
            ||..:..||.|.|.||:||:::...|.::.::|:..|.:|||:|||.||.||.:||..||.::|.
  Rat   324 LFTSDACGLSDAAHIESLQEKSQCALEEYVRSQYPNQPSRFGKLLLRLPSLRTVSSSVIEQLFFV 388

  Fly   565 RTIGNTPMEKVLCDM 579
            |.:|.||:|.::.||
  Rat   389 RLVGKTPIETLIRDM 403

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hr51	NP_611032.2	NR_DBD_PNR	103..194	CDD:143528	50/90 (56%)
		NR_LBD_Tlx_PNR_like	354..569	CDD:132748	87/214 (41%)
Nr2f1	NP_112392.2	NR_DBD_COUP_TF	83..155	CDD:143516	47/72 (65%)
		NR_LBD_COUP-TF	181..416	CDD:132746	99/351 (28%)