Protein Alignment Hr51 and rxraa

DIOPT Version :10

• Sequence 1: NP_611032.2
• Gene: Hr51 / 36702
• FlyBaseID: FBgn0034012
• Length: 582
• Species: Drosophila melanogaster
• Sequence 2: XP_005161240.1
• Gene: rxraa / 555578
• ZFINID: ZDB-GENE-070314-2
• Length: 500
• Species: Danio rerio
• Alignment Length: 643
• Identity: 169/643 - (26%)
• Similarity: 246/643 - (38%)
• Gaps: 224/643 - (34%)

  Fly     9 ETRP-SSQELHSPQRHCYTPPPAPMHGQAP----------------------PPTSTGVAPPTQP 50
            ||:| .|.....||  |..||| |..|:|.                      ..||:.::.||..
Zfish     2 ETKPFLSLGFLKPQ--CSLPPP-PQRGRAEACTCFSGMCALHQRRLSTDCTGQVTSSPLSSPTSH 63

  Fly    51 PPPHPA--APNV--PNGRLLS-----------------------WNHSAAAAAA--AAAAQAAAN 86
            ...||:  :|..  |:|.|.|                       ..||.|:...  ..:.....|
Zfish    64 RGMHPSLLSPTSLGPSGSLHSPISTLSSPMNGLGSPFSVISSPMGPHSMASPGVGYGPSISPQLN 128

  Fly    87 S-MNHSSAAEG-------SSMTRIKGQNLGL-------ICVVCGDTSSGKHYGILACNGCSGFFK 136
            | ||..|::|.       :.:.::..|..|.       ||.:|||.|||||||:.:|.||.||||
Zfish   129 SPMNSVSSSEDIKPPLGLNGVMKVPAQPSGTPLSLTKHICAICGDRSSGKHYGVYSCEGCKGFFK 193

  Fly   137 RSVRRKLIYRCQAGTGRCVVDKAHRNQCQACRLKKCLQMGMNKD-----AVQNERQPRNTATIRP 196
            |:||:.|.|.|:.... ||:||..||:||.||.:|||.|||.::     |||.|||   .|..|.
Zfish   194 RTVRKDLTYTCRDNKD-CVIDKRQRNRCQYCRYQKCLAMGMKREVLLHTAVQEERQ---RAKERS 254

  Fly   197 ETLREMEHGRALREAAVAVGVFGPPVLLSPPCYGSGLLPPPSLGSLPTGRLLHHNHLTSSMQLAA 261
            |  .|:|...:..|                              .:|..::|       ..:||.
Zfish   255 E--NEVESTSSANE------------------------------DMPVEKIL-------EAELAV 280

  Fly   262 NHMGAGSFPMFNAAGVHHSPKEKAYGMEMATSGNVSHSTNSSSNHSIDPSSPAPENAKEINIAGG 326
                              .||.:.|                     |:.:.|.|.|
Zfish   281 ------------------EPKTETY---------------------IETNVPMPSN--------- 297

  Fly   327 SVSSVSSSSPTMENDNDDDSIDVTNDNEEPHAVSRSDSSFIMPQFMSPNLYTHQHETVYETSARL 391
                    ||     ||    .|||                                :.:.:.:.
Zfish   298 --------SP-----ND----PVTN--------------------------------ICQAADKQ 313

  Fly   392 LFMAVKWAKNLPSFARLSFRDQVILLEESWSELFLLNAIQWCIPLDPTGCALFSVAEHCNNLENN 456
            ||..|:|||.:|.|:.|...||||||...|:||.:.:.....|.:.........:..|.|:..:.
Zfish   314 LFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSA 378

  Fly   457 ANGDTCITKEELAADVRTLHEIFCKYKAVLVDPAEFACLKAIVLFRPETRGLKDPAQIENLQDQA 521
            ..|         |...|.|.|:..|.:.:.:|..|..||:|||||.|:::||.:|.::|.|:::.
Zfish   379 GVG---------AIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPGEVEALREKV 434

  Fly   522 HVMLSQHTKTQFTAQIARFGRLLLMLPLLRMISSHKIESIYFQRTIGNTPMEKVLCDM 579
            :..|..:.|.::..|..||.:|||.||.||.|....:|.::|.:.||:||::..|.:|
Zfish   435 YASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEM 492

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hr51	NP_611032.2	NR_DBD_PNR	103..194	CDD:143528	50/102 (49%)
		NR_LBD_Tlx_PNR_like	354..569	CDD:132748	58/214 (27%)
rxraa	XP_005161240.1	Nuc_recep-AF1	63..160	CDD:463363	18/96 (19%)
		NR_DBD_RXR	166..247	CDD:143514	44/81 (54%)
		NR_LBD_RXR_like	267..478	CDD:132741	75/323 (23%)