Protein Alignment Hr51 and Hnf4

DIOPT Version :9

• Sequence 1: NP_611032.2
• Gene: Hr51 / 36702
• FlyBaseID: FBgn0034012
• Length: 582
• Species: Drosophila melanogaster
• Sequence 2: NP_723413.1
• Gene: Hnf4 / 44544
• FlyBaseID: FBgn0004914
• Length: 732
• Species: Drosophila melanogaster
• Alignment Length: 619
• Identity: 152/619 - (24%)
• Similarity: 232/619 - (37%)
• Gaps: 213/619 - (34%)

  Fly     3 KEENSSETRPSSQELHSPQRHCYTPPPAPMHGQAPPPTSTGVAPPTQPPPPHPAAPNVPNG---- 63
            :..:||.:|.:|.:  ..:.|.       ||..|   .::.....:||..|...|.: |||
  Fly    47 RRRDSSASRTASSD--ESESHI-------MHADA---LASAYPAASQPHSPIGLALS-PNGGGLG 98

  Fly    64 ------------RLLSWNHSAAAAAAAAAAQAAAN-----SMNHSSAAEGS-------SMTRIKG 104
                        .|.:.|.:|.:|...:|:..:.|     |.|::.:..||       .:.:.:.
  Fly    99 LSNSSNQSSENFALCNGNGNAGSAGGGSASSGSNNNNSMFSPNNNLSGSGSGTNSSQQQLQQQQQ 163

  Fly   105 QNLGLICVVCGDTSSGKHYGILACNGCSGFFKRSVRRKLIYRCQAGTGRCVVDKAHRNQCQACRL 169
            |....:|.:|||.::|||||..:|:||.|||:||||:...|.|:... .|||||..||||:.|||
  Fly   164 QQSPTVCAICGDRATGKHYGASSCDGCKGFFRRSVRKNHQYTCRFAR-NCVVDKDKRNQCRYCRL 227

  Fly   170 KKCLQMGMNKDAVQNERQP---RNTATIRPETLREMEHGRALREAAVAVGVFGPPVLLSPPCYGS 231
            :||.:.||.|:||||||..   |.|:...|:.                               |:
  Fly   228 RKCFKAGMKKEAVQNERDRISCRRTSNDDPDP-------------------------------GN 261

  Fly   232 GLLPPPSLGSLPTGRLLHHNHLTSSMQLAANHMGAGSFPMFNAAGVHHSPKEKAYGMEMATSGNV 296
            ||    |:.||....
  Fly   262 GL----SVISLVKAE-------------------------------------------------- 272

  Fly   297 SHSTNSSSNHSIDPSSPAPENAKEINIAGGSVSSVSSSSPTMENDNDDDSIDVTNDNEEPHAVSR 361
            :.|..|.:..:::|                             |.|:    |::|
  Fly   273 NESRQSKAGAAMEP-----------------------------NINE----DLSN---------- 294

  Fly   362 SDSSFIMPQFMSPNLYTHQHETVYETSARLLFMAVKWAKNLPSFARLSFRDQVILLEESWSELFL 426
                   .||.|.|       .|.|:..:.|...|:|||.:|:|..|...|||.||.....|..|
  Fly   295 -------KQFASIN-------DVCESMKQQLLTLVEWAKQIPAFNELQLDDQVALLRAHAGEHLL 345

  Fly   427 LNAIQWCIPLD-----PTGCALFSVAEHC------NNLENNANGDTCITKEELAADVRTLHEIFC 480
            |...:..:.|.     ...|.   :..||      .||:.:..|            .|.:.|:..
  Fly   346 LGLSRRSMHLKDVLLLSNNCV---ITRHCPDPLVSPNLDISRIG------------ARIIDELVT 395

  Fly   481 KYKAVLVDPAEFACLKAIVLFRPETRGLKDPAQIENLQDQAHVMLSQHTKTQFTAQIARFGRLLL 545
            ..|.|.:|..||||:||:|.|.|..:||.:|.:|::|:.|....|..:...:......|||.:||
  Fly   396 VMKDVGIDDTEFACIKALVFFDPNAKGLNEPHRIKSLRHQILNNLEDYISDRQYESRGRFGEILL 460

  Fly   546 MLPLLRMISSHKIESIYFQRTIGNTPMEKVLCDM 579
            :||:|:.|:...||.|.|.:..|...::.:|.:|
  Fly   461 ILPVLQSITWQMIEQIQFAKIFGVAHIDSLLQEM 494

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hr51	NP_611032.2	NR_DBD_PNR	103..194	CDD:143528	47/93 (51%)
		NR_LBD_Tlx_PNR_like	354..569	CDD:132748	63/225 (28%)
Hnf4	NP_723413.1	NR_DBD_HNF4A	170..245	CDD:143518	43/75 (57%)
		NR_LBD_HNF4_like	264..494	CDD:132729	75/351 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45444776
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24083
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.940